Results 101 to 110 of about 60,978 (228)

Circular RNAs of UDP-Glycosyltransferase (UGT) Genes Expand the Complexity and Diversity of the UGT Transcriptome [PDF]

open access: bronze, 2021
Dong Hu   +4 more
openalex   +1 more source

An OGT Missense Variant With Impaired Enzyme Activity in a Child With Severe Developmental Delay and Hepatoblastoma

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 502-510, February 2026.
ABSTRACT O‐GlcNAc transferase (OGT) and its antagonist O‐GlcNAcase (OGA) regulate protein O‐GlcNAcylation, a highly conserved post‐translational modification involved in metabolic sensing. Pathogenic variants in the OGT gene cause an X‐linked congenital disorder of glycosylation (OGT‐CDG) presenting developmental delay, hypotonia, intellectual ...
Alfonso Manuel D'Alessio   +12 more
wiley   +1 more source

The ZmHSF08-ZmUGT92A1 module regulates heat tolerance by altering reactive oxygen species levels in maize

open access: yesCrop Journal
GTs (Glycosyltransferases) are important in plant growth and abiotic stresses. However, its role in maize heat response is far from clear. Here, we describe the constitutively expressed UDP-glycosyltransferase ZmUGT92A1, which has a highly conserved PSPG
Hao Li   +6 more
doaj   +1 more source

Metabolic reprogramming of efferocytosis in the tumour microenvironment: From apoptotic‐cell clearance to therapeutic targeting

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley   +1 more source

Fusarium culmorum Tri genes and barley Hvugt13248 gene transcription in infected barley cultivars

open access: yesPlant Protection Science, 2019
The transcription activities of genes somehow associated with the mycotoxin deoxynivalenol (DON) biosynthesis, namely Fusarium Tri genes, and the barley gene coding for UDP-glycosyltransferase (HvUGT13248) on different genetic backgrounds were compared ...
Zuzana Faltusová   +5 more
doaj   +1 more source

Estrone‐α‐2‐Deoxy‐Glucoside as a Targeted Therapy for Triple‐Negative Breast Cancer: Aromatase Inhibition and Cytotoxicity

open access: yesChemical Biology &Drug Design, Volume 107, Issue 2, February 2026.
Estrone‐α‐2DG, synthesized via a one‐pot multi‐enzyme system, selectively inhibits aromatase (IC50 = 0.101μM) and triple negative breast cancer cells (IC50 = 20.46 μM), offering a dual function therapeutic scaffold. ABSTRACT Aromatase inhibitors (AIs) are vital in the treatment of estrogen‐dependent breast cancer, especially in postmenopausal women. In
Tzu‐Yu Huang   +5 more
wiley   +1 more source

Genome-wide characterization of the tomato UDP-glycosyltransferase gene family and functional identification of SlUDPGT52 in drought tolerance [PDF]

open access: diamond, 2023
Ling Qiu   +11 more
openalex   +1 more source

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