Results 61 to 70 of about 60,978 (228)

NleB2 from enteropathogenic Escherichia coli is a novel arginine-glucose transferase effector.

open access: yesPLoS Pathogens, 2021
During infection, enteropathogenic Escherichia coli (EPEC) and enterohaemorrhagic E. coli (EHEC) directly manipulate various aspects of host cell function through the translocation of type III secretion system (T3SS) effector proteins directly into the ...
Cristina Giogha   +7 more
doaj   +1 more source

Synthesis and Preliminary Evaluation of Biological Activity of Glycoconjugates Analogues of Acyclic Uridine Derivatives

open access: yesMolecules, 2018
Herein we present the methodology for obtaining glycosyltransferase inhibitors, analogues of natural enzyme substrates of donor-type: UDP-glucose and UDP-galactose.
Roman Komor   +3 more
doaj   +1 more source

A freezing responsive UDP-glycosyltransferase improves potato freezing tolerance via modifying flavonoid metabolism

open access: yesHorticultural Plant Journal
Potato (Solanum tuberosum) is a globally important staple crop. However, cultivated potato varieties are highly sensitive to low temperatures. The molecular mechanisms underlying freezing resistance in potatoes remain poorly understood.
Huihui Bao   +6 more
doaj   +1 more source

Identification of UDP Glycosyltransferase 3A1 as a UDP N-Acetylglucosaminyltransferase [PDF]

open access: yesJournal of Biological Chemistry, 2008
The UDP glycosyltransferases (UGT) attach sugar residues to small lipophilic chemicals to alter their biological properties and enhance elimination. Of the four families present in mammals, two families, UGT1 and UGT2, use UDP glucuronic acid to glucuronidate bilirubin, steroids, bile acids, drugs, and many other endogenous chemicals and xenobiotics ...
Mackenzie, Peter Ian   +5 more
openaire   +3 more sources

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Study on Revealing Peanut-Related Disease Prevention Gene Clusters via Whole Transcriptome Sequencing

open access: yesAgriculture, 2023
Root rot caused by Fusarium oxysporum is a serious root disease that affects the growth and yield of peanut crops worldwide. Identifying resistance genes is of great significance for both conventional and molecular breeding.
Hongbo Du, Nan Lu, Chuanrong Li
doaj   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

open access: yesFood Frontiers, EarlyView.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani   +3 more
wiley   +1 more source

Identification of an apiosyltransferase in the plant pathogen Xanthomonas pisi. [PDF]

open access: yesPLoS ONE, 2018
The rare branched-chain sugar apiose, once thought to only be present in the plant kingdom, was found in two bacterial species: Geminicoccus roseus and Xanthomonas pisi.
James Amor Smith, Maor Bar-Peled
doaj   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui   +4 more
wiley   +1 more source

UGT440A1 Is Associated With Motility, Reproduction, and Pathogenicity of the Plant-Parasitic Nematode Bursaphelenchus xylophilus

open access: yesFrontiers in Plant Science, 2022
Pine wilt disease (PWD) caused by Bursaphelenchus xylophilus is considered a major threat to pine forests worldwide. Uridine diphosphate (UDP)-glycosyltransferases (UGTs) catalyze the conjugation of small lipophilic compounds with sugars and play crucial
Min Wang   +6 more
doaj   +1 more source

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