Results 161 to 170 of about 81,476 (261)

Synthesis and Evaluation of Iminosugar-Based Analogs of UDP-GlcNAc as Putative OGT Inhibitors. [PDF]

ChemMedChem
Auberger N, Tran TV, Lemaire Q, Busmann J, Lacritick M, Mortuaire M, Schulz C, Vercoutter-Edouart AS, Pâris A, Vocadlo D, Lafite P, Vincent SP, Lefebvre T, Blériot Y.   +13 more
europepmc   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Statin-induced lipid carrier stress reveals a conserved vulnerability in β-lactam-resistant Gram-positive bacteria. [PDF]

Nat Commun
Torrens G, Bisset SW, López-Bravo M, Johansson AF, Lopez D, Cava F.   +5 more
europepmc   +1 more source

Targeted Knockout of CYP79A1 Reduces Cyanogenic Potential in Grain Sorghum

Plant Biotechnology Journal, EarlyView.
Evan D. Groover, Jianqiang Shen, Kiflom Aregawi, Sophie Li, Shahar Schwartz, Brian J. Staskawicz, Peggy G. Lemaux, David F. Savage   +7 more
wiley   +1 more source

Post‐exercise ketone supplementation improves endurance performance and mitochondrial adaptations during an 8‐week endurance training intervention

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐eight trained males completed 8 weeks of supervised indoor cycling training, receiving post‐exercise and pre‐sleep ketone monoester (KE, n = 14) or isocaloric placebo (CON, n = 14). Both groups improved 30 min time‐trial performance with training, but KE achieved a 4% higher power output than CON at the end of the training
Ruben Robberechts, Youri Bekhuis, Myrthe Stalmans, Wout Lauriks, Martijn Kusters, Karim Taha, Thomas Rosseel, Guido Claessen, Chiel Poffé   +8 more
wiley   +1 more source

P2RY6⁺ tumor-associated macrophages as a therapeutic target: suppressing tumor growth and enhancing chemosensitivity in triple-negative breast cancer. [PDF]

Cell Oncol (Dordr)
Wang X, Ma M, Zhang M, Lu H, Liu Y, Zhou Y, Han B.   +6 more
europepmc   +1 more source

Comparative Pharmacokinetics of Six Bioactive Constituents From Danggui Jixueteng Decoction in Normal and Myelosuppressive Rats

Analytical Science Advances, Volume 7, Issue 2, December 2026.
ABSTRACT This study compared the pharmacokinetics of six constituents from Danggui Jixueteng Decoction in normal versus carboplatin‐induced myelosuppressive rats. A rapid, sensitive ultra‐high performance liquid chromatography‐tandem mass spectrometry method was developed and validated for simultaneous quantification of six diverse constituents (8‐O ...
Mingxin Guo, Yingjie Liu, Zhiqiang Hu, Xiayu Liu   +3 more
wiley   +1 more source

Advances in the heterologous biosynthesis of QS saponins: a review. [PDF]

Microb Cell Fact
Tian Y, Zhang W, Tang M, Wen M, Qiao J, Zhu H, Li W, Caiyin Q.   +7 more
europepmc   +1 more source

UDP-4 [PDF]

, 2020
openaire   +1 more source

DPYD and UGT1A1 Genotype‐Based Dosing for Fluoropyrimidines and Irinotecan Chemotherapy: Variant‐Specific Impact on Treatment Intensity and Toxicity

International Journal of Cancer, Volume 159, Issue 10, Page 2512-2524, 15 November 2026.
Pre‐treatment DPYD and UGT1A1 genotyping is increasingly used to prevent fluoropyrimidine‐ and irinotecan‐related toxicity, but variant‐specific real‐world effects remain unclear. In an unselected cohort of cancer patients with actionable genotypes, genotype‐driven dosing improved safety while preserving treatment exposure in high‐risk DPYD c.1905+1G>A
Martina Gambron, Elena Peruzzi, Samantha Perfler, Marcella Montico, Riccardo Cecchin, Elena De Mattia, Michele Spina, Camilla Lisanti, Serena Corsetti, Luisa Foltran, Fabio Puglisi, Rossana Roncato, Erika Cecchin   +12 more
wiley   +1 more source