Results 171 to 180 of about 211,061 (307)

A flow-level dataset of WireGuard tunnel traffic with matched encrypted-side features and application labels. [PDF]

Data Brief
Razooqi YS, Pekar A.
europepmc   +1 more source

Transcript correlation analysis for the identification of novel plant genes involved in iron metabolism and beyond: what next?

Plant Biology, EarlyView.
Transcript correlation analysis allowed the identification of several key nodes in the complex regulatory network of plant iron metabolism. Abstract Arabidopsis thaliana was the first plant genome to be fully sequenced, almost a quarter of a century ago, thanks to The Arabidopsis Genome Initiative, with contributions from scientists worldwide.
I. Murgia, P. Morandini
wiley   +1 more source

Uridine diphosphate drives myeloid differentiation and functional reprogramming through dynamic transcriptional network. [PDF]

Front Immunol
Giordano C, Gentile D, Straface E, Gallo R, Cristiani CM, Abatino A, Pastore A, Celano M, Arcucci A, Albano F, Falco G, Veneziano C, Santamaria G, Aversa I, Isdraele Romano L, Palmieri C, Fiume G.   +16 more
europepmc   +1 more source

Hyperglycaemia‐induced reactive oxygen species production in cardiac ventricular myocytes differs among mammals

The Journal of Physiology, EarlyView.
Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu, Maria J. Baier, Risto‐Pekka Polonen, Zhandi Liao, Jody L. Martin, Kenneth S. Ginsburg, Julian Mustroph, Donald M. Bers   +7 more
wiley   +1 more source

Proteasomal-dependent endothelial P2Y₆ receptor downregulation as an adaptive mechanism limiting monocyte adhesion during intestinal schistosomiasis. [PDF]

Purinergic Signal
Oliveira NF, Monteiro MMLV, Crepaldi LD, Coutinho-Silva R, Savio LEB, Silva CLM.   +5 more
europepmc   +1 more source

Physiological and anatomical determinants of placental drug transfer

The Journal of Physiology, EarlyView.
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis, Anandita Umapathy, Jane K. Cleal, Bram G. Sengers   +3 more
wiley   +1 more source

A characterization of recombinant Arabidopsis FRIABLE1 (FRB1) reveals robust rhamnogalacturonan-I rhamnosyltransferase activity and critical catalytic residues. [PDF]

J Biol Chem
Robichaux KJ, Blea MN, Amos RA, Huang C, Mohnen D, Wallace IS.   +5 more
europepmc   +1 more source

Engineering of Amygdalin Biosynthesis in Rice Endosperm for Pharmaceutical Production and Sitophilus oryzae Resistance

Plant Biotechnology Journal, EarlyView.
Ke Chen, Nan Chai, Shaotong Chen, Chanjuan Ye, Kangli Sun, Jie Guo, Xinqiao Zhou, Dagang Chen, Juan Liu, Yanduan Hu, Yi Zou, Rui Cao, Shu Jiang, Bocai Tang, Qinlong Zhu, Chuanguang Liu, Jiantao Tan   +16 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Structural insights into SetA-mediated Rab1 glucosylation and PI3P-guided localization during early <i>Legionella</i> infection. [PDF]

Proc Natl Acad Sci U S A
Im HN, Lee Y, Song Y, Hahn H, Jeon H, Shin D, Lee S, Kim KH, Kim KT, Suh SW, Jang DM, Kim HS.   +11 more
europepmc   +1 more source