Results 191 to 200 of about 211,061 (307)

Structural and Functional Analyses of <i>Trypanosoma brucei</i> Nucleoside Diphosphate Kinase. [PDF]

ACS Omega
Makori P, Boeckman MP, David HS, Payne F, Gatling M, Greer C, Hayes D, Jefferson A, Maxwell M, Smith C, Watson J, Williams L, Barkley J, Pepper C, Zininga T, Subramanian S, Abramov A, Gardberg AS, Edwards TE, Staker BL, Stewart LJ, Myler PJ, Asojo OA, Jeje O, Fanucchi S, Achilonu I, Smith CL, Chakafana G.   +27 more
europepmc   +1 more source

Parent/caregiver needs during pediatric genome‐wide sequencing: A scoping literature review

Journal of Genetic Counseling, Volume 35, Issue 3, June 2026.
Abstract The integration of genome‐wide sequencing (GWS) including whole‐exome and whole‐genome sequencing, has transformed pediatric diagnostics, yet the needs of parents and caregivers during this process remain insufficiently explored. This scoping review aims to synthesize current knowledge on parental and caregiver needs across the GWS process in ...
Priyanka Murali, Joon‐Ho Yu
wiley   +1 more source

Synthesis of Polyhydroxylated Pyrrolidinyl Analogs of Sugar Nucleotides. Experimental and Computational Studies on Their Interactions With GalNAC-T's. [PDF]

Chembiochem
Merino P, Juste V, Montesa A, Pereira S, Orta S, Pedrón M, Jiménez AI, Martín-Santamaría S, Hurtado-Guerrero R, Delso I, Tejero T.   +10 more
europepmc   +1 more source

Disarming the Pathogen's Metabolic Weapon: A Novel Route to Durable Disease Resistance

Modern Agriculture, Volume 4, Issue 1, June 2026.
Two routes to sugar acquisition in pathogenic bacteria and corresponding ‘pathogen‐starvation’ strategies. TAL effectors activate plant SWEET transporters to promote sucrose efflux into the apoplast, which can be blocked by editing SWEET promoter effector‐binding elements to prevent TAL binding. The T3E AvrBs2 converts host UDP‐galactose into xanthosan,
Yixuan Mi, Yuheng Yang
wiley   +1 more source

Phylogenetic analysis reveals diversity in glycan biosynthesis in "<i>Candidatus</i> Accumulibacter". [PDF]

Biofilm
Eerden SA, Abeel T, van Loosdrecht MCM, Roy S.   +3 more
europepmc   +1 more source

A Roadmap for Breeding Sweet Tomatoes

Modern Agriculture, Volume 4, Issue 1, June 2026.
This graphical abstract outlines four breeding strategies for enhancing sugar content and sweetness in tomato fruits: (1) Identification of key genes and functional variant loci regulating fruit sugar accumulation through systematic germplasm collection, genome‐wide association studies (GWAS), map‐based cloning, and reverse genetics approaches.
Jie Chen, Hongjun Lyu, Jinzhe Zhang
wiley   +1 more source

Carnosine protects human microglia against Aβ oligomers through a multimodal mechanism of action: inhibition of oxidative stress, rescue of cellular energy status, and enhancement of phagocytosis. [PDF]

Front Immunol
Privitera A, Cardaci V, Zupan MC, Di Pietro L, Carota G, Sibbitts J, Mangione R, Graziani A, Buccarello L, Bellia F, Di Pietro V, Lazzarino G, Lunte SM, Hartley MD, Caraci F, Tavazzi B, Maiani E, Amorini AM, Lazzarino G, Caruso G.   +19 more
europepmc   +1 more source

UDP-Glukuronyltransferase [PDF]

, 2017
A. M. Gressner, O. A. Gressner
openaire   +2 more sources

Acid ceramidase overactivity drives ceramide loss, leading to atopic dry skin and Th2‐skewed immune polarization

The Journal of Pathology, Volume 269, Issue 2, Page 232-247, June 2026.
Abstract Ceramide deficiency in the stratum corneum (SC) is a key etiological factor in atopic dermatitis (AD). To clarify the direct role of SC ceramide depletion in impairing SC barrier and water‐holding functions and in initiating AD‐like skin symptoms and disease‐specific molecular alterations, we generated Tg mice overexpressing a mutant form of ...
Mariko Takada, Miho Sashikawa‐Kimura, Yusuke Ohno, Md Razib Hossain, Xiaonan Xie, Kazuhisa Iwabuchi, Mayumi Komine, Mamitaro Ohtsuki, Genji Imokawa   +8 more
wiley   +1 more source

P.F. Strawson (1919-2006)

Isegoría, 2006
M. E. Orellana Benado
doaj