Results 251 to 260 of about 97,609 (305)

Decoding the Hexosamine Biosynthesis Pathway: Implications for Novel Therapeutic Strategies in Sarcoma. [PDF]

J Cell Physiol
Rahimizadeh P, Miallot R, De Bellis C, Jolivet P, Przybyl J.   +4 more
europepmc   +1 more source

Uridine diphosphate <i>N</i>-acetylglucosamine homeostasis via CgNgk1 kinase modulates chitin levels and cell-wall integrity in <i>Candida glabrata</i>. [PDF]

FEMS Microbes
Yamada R, Nakayama H, Yoshikawa S, Karita S, Umekawa M.   +4 more
europepmc   +1 more source

Systematic metabolic engineering of <i>Escherichia coli</i> for high-level production of pseudouridine via pathway optimization and precursor enhancement. [PDF]

Synth Syst Biotechnol
Song J, Shen W, Xia Y, Zhou L, Zhou Y, Yang H, Chen X.   +6 more
europepmc   +1 more source

Structural basis of fungal β-1,3-glucan synthase inhibition by caspofungin. [PDF]

Nature
Ren Z, Chhetri A, Liu C, Offner S, Sharma K, Borgnia MJ, Im W, Yokoyama K, Lee SY.   +8 more
europepmc   +1 more source

Iterative Bump-and-hole engineering creates a bioorthogonal reporter for N -acetylglucosaminyltransferase I

Liu Y, Pieters S, Bineva-Todd G, Sagiroglugil M, Burnap SA, Hoddle F, Cioce A, Ohara A, Bruemmer K, Bertozzi CR, Polizzi K, Struwe WB, Rovira C, Schumann B.   +13 more
europepmc   +1 more source

Enhanced UDP-glucose and UDP-galactose by homologous overexpression of UDP-glucose pyrophosphorylase in Lactobacillus casei

Journal of Biotechnology, 2011
UDP-sugars are widely used as substrates in the synthesis of oligosaccharides catalyzed by glycosyltransferases. In the present work a metabolic engineering strategy aimed to direct the carbon flux towards UDP-glucose and UDP-galactose biosynthesis was successfully applied in Lactobacillus casei.
Jesus Rodríguez-Díaz, Maria J Yebra
exaly   +5 more sources

Preparation of UDP-galacturonic acid using UDP-sugar pyrophosphorylase

Analytical Biochemistry, 2006
UDP-galacturonic acid, the activated form of galacturonic acid (GalUA), is synthesized both de novo and by salvage pathways. The UDP-GalUA pyrophosphorylase gene involved in the salvage pathway has not been identified. Here we show that UDP-sugar pyrophosphorylase from Pisum sativum with a broad specificity has UDP-GalUA pyrophosphorylase activity. The
Ohashi, Takao, Cramer, Nicolai, Ishimizu, Takeshi, Hase, Sumihiro   +3 more
openaire   +3 more sources

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UDP-Glucuronosyltransferases

Current Drug Metabolism, 2000
Glucuronidation represents a major pathway which enhances the elimination of many lipophilic xenobiotics and endobiotics to more water-soluble compounds. The UDP-glucuronosyltransferase (UGT) family catalyzes the glucuronidation of the glycosyl group of a nucleotide sugar to an acceptor compound (aglycone) at a nucleophilic functional group of oxygen ...
C D, King, G R, Rios, M D, Green, T R, Tephly   +3 more
openaire   +2 more sources