Results 231 to 240 of about 97,609 (305)

<i>De novo</i> biosynthesis of eriocitrin in <i>Saccharomyces cerevisiae</i> through deep learning-guided enzyme screening and systematic metabolic engineering. [PDF]

Synth Syst Biotechnol
Lu Q, Tan X, Zhang S, Wang Y, Zhao Y, Liu J, Hu F, Zuo S, Chen J, Fan L, Ding S, Xiao Z, Shan Y.   +12 more
europepmc   +1 more source

Genomic and Sex Contributions to Interindividual Variability in Pitavastatin Bioavailability

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.
ABSTRACT Aim This study investigates pharmacogenetic determinants of pitavastatin disposition using a candidate‐gene approach. Methods In 48 healthy volunteers, 138 variants across 40 genes involved in drug metabolism and transport were analysed to assess their relationship with pitavastatin pharmacokinetics, alongside the influence of sex and ...
Eva González‐Iglesias, Sofía Moreno‐Pérez de Villar, Dolores Ochoa, Manuel Román, Jesús Novalbos, Samuel Martín‐Vilchez, Alejandro de Miguel, Francisco Abad‐Santos   +7 more
wiley   +1 more source

A lightweight machine learning approach for DDoS detection and classification. [PDF]

Sci Rep
Ebrahem O, Dowaji S, Alhammoud S.
europepmc   +1 more source

Ontogenetic Sequence of Differential Gene Expression in Predator‐Induced Daphnia pulex

Molecular Ecology, Volume 35, Issue 13, July 2026.
ABSTRACT In response to predators, many Daphnia species develop inducible morphological defenses. These traits are phenotypically plastic, meaning their production is suppressed in the absence of the predator. While previous studies have identified several neurohumoral factors and candidate genes involved in the development of the defenses, the ...
Andrey Rozenberg, Linda C. Weiss, Tatjana Schwarz, Nancy Kühne, Uwe John, Ralph Tollrian   +5 more
wiley   +1 more source

Molecular basis of collagen galactosylation by GLT25D1. [PDF]

Nat Commun
Sun H, Zhang M, Shi Y, Zhang D, Hua Z, Yang P, Yang Y, Li J, Chen J, Wang C, Li P, Hu X, Ke Y, Zhang M, Liu X, Yu H.   +15 more
europepmc   +1 more source

Sweet Potato Gene Clusters Control Anthocyanin Biosynthesis and Leaf Morphology

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4500-4527, July 2026.
ABSTRACT Sweet potato (Ipomoea batatas) exhibits diversity in pigmentation and leaf morphology, yet the genetic architecture and regulatory organisation underlying these traits remain poorly resolved, particularly with respect to organ‐specific control.
Dong An, Tiechen Shen, Shiyu Wu, Yanshen Li, Weijuan Fan, Mengxiao Yan, Yinghui Meng, Xinyi Wang, Ximing Xu, Zunfu Lv, Ling Yuan, Jun Yang, Guoquan Lu, Hongxia Wang   +13 more
wiley   +1 more source

Structure-coevolution dual-guided engineering of C-glycosyltransferase enables high-level biosynthesis of vitexin in <i>Yarrowia lipolytica</i>. [PDF]

Synth Syst Biotechnol
Shi CQ, Chen YJ, Yang WL, Zheng S, Cai R, Hou J, Wang DQ, Sheng JZ.   +7 more
europepmc   +1 more source

The Transcription Factor OsWRKY64 Interacts With OsART1 to Positively Regulate Al Resistance in Rice

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4656-4671, July 2026.
A proposed working model illustrating the cooperative regulation of Al tolerance by OsWRKY64 and OsART1 in rice. Under Al stress conditions in acidic soil, the transcription factor OsART1 directly binds to the promoter of OsWRKY64 to activate its transcription. The synthesized OsWRKY64 protein then physically interacts with OsART1 in the nucleus.
Changzhao Chen, Qiang Zhang, Yonggang Xu, Jibo Yang, Jing Yan, Mengmeng Jiang, Lu Zheng, Tingwu Liu, Jiu Huang, Renfang Shen, Xiaofang Zhu   +10 more
wiley   +1 more source

Structural and Functional Analyses of <i>Trypanosoma brucei</i> Nucleoside Diphosphate Kinase. [PDF]

ACS Omega
Makori P, Boeckman MP, David HS, Payne F, Gatling M, Greer C, Hayes D, Jefferson A, Maxwell M, Smith C, Watson J, Williams L, Barkley J, Pepper C, Zininga T, Subramanian S, Abramov A, Gardberg AS, Edwards TE, Staker BL, Stewart LJ, Myler PJ, Asojo OA, Jeje O, Fanucchi S, Achilonu I, Smith CL, Chakafana G.   +27 more
europepmc   +1 more source