Results 121 to 130 of about 7,468 (177)
Synthesis of new type of cephalosporin derivatives using ugi reaction
Munkám során új típusú β-laktámokat hoztam létre négy komponensű Ugi reakcióval. Ezek után új laktám vázas molekulákat antibakteriális vizsgálatokon tanulmányozták.
Nagy, Zsolt László
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Use of Ugi-three component reaction for the synthesis of poly(α-amino amide)s
Multicomponent reactions (MCRs), in which three or more compounds react and form a product containing essentially all atoms of the starting reagents, have been thoroughly exploited in organic synthesis for preparing complex molecules.
Lecomte, Philippe +3 more
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Ivar Ugi: An Exceptional Scientist and Human being. In Memorial Ivar Ugi [PDF]
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Peptit yapısında penisilinlerin ugi reaksiyonu ile sentezi
β-Laktam halkası içeren 6-aminopenisilanik asit ve sefalosporanik asit içeren bileşiklerin biyolojik aktif bileşikler olduğu bilinmektedir. β-Laktam halkası türevleri özellikle antibakteriyel ve antiparaziter özelliğe sahip olduğu bilinir.
ANBER ANBER
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Cyclic Imines in Ugi and Ugi-Type Reactions
ACS Combinatorial Science, 2020Ugi four-component reactions (U-4CRs) are widely recognized as being highly efficient for the synthesis of pseudopeptides. However, the products of these reactions are not so interesting as drug candidates because they are not conformationally restricted enough for a potent interaction with biological targets.
Ahmad Shaabani +2 more
exaly +3 more sources
Insight into the Mechanisms of the Multicomponent Ugi and Ugi–Smiles Reactions by ESI‐MS(/MS)
AbstractThe mechanisms of the Ugi and Ugi–Smiles reactions were investigated by using finely selected reaction conditions that allowed all of the intermediates to be “fish‐out” and characterized by ESI‐MS/MS. New insight into the Ugi and Ugi–Smiles reaction mechanisms is provided without using charge‐tagged reagents.
IACOBUCCI, CLAUDIO +3 more
openaire +2 more sources
A diastereoselective synthesis of pseudopeptidic hydantoins by an Ugi/cyclization/Ugi sequence
Tetrahedron, 2012Abstract A diastereoselective synthesis of helix-forming pseudopeptidic hydantoins by an Ugi 4CC/cyclization/reduction/Ugi 4CC sequence of reactions, giving mainly the l -adduct when benzoic acids were used, is described.
Maria García-Valverde
exaly +2 more sources
Recent Access to Polycycles via Post-Ugi Reactions
Ugi reactions have been widely studied due to their mild reaction conditions, high structural variability, and wide applications. Ugi adducts have proved to be highly efficient for different kinds of post-transformations by carefully choosing the ...
Liangliang Song
exaly +2 more sources

