Results 101 to 110 of about 14,737 (217)
Peptide array functionalization via the Ugi four-component reaction
, 2017 The Ugi four-component reaction was investigated as a tool for the functionalization of peptide arraysviapost-synthetic side-chain modification as well as integration of an Ugi unit into a growing peptide chain.
M. A. R. Meier +9 more
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JCO Global OncologyPURPOSEThe purpose of this study was to identify participation determinants among high-risk individuals in risk-stratified upper GI (UGI) cancer screening.METHODSThis sequential mixed-methods study was conducted in a population-based UGI cancer screening
Zeyu Yan +21 more
doaj +1 more source
Interrupted Ugi and Passerini Reactions: An Underexplored Treasure Island
, 2018 The formation of the key short-lived intermediate nitrilium ion in the Passerini and Ugi reactions was recognized early in the discovery of these two-multicomponent transformations.
Andrea Basso +13 more
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Perceived influence of urban green infrastructure on quality of life in Lagos Metropolis, Nigeria
Town and Regional PlanningQuality of life (QoL) in urban areas is closely linked to the availability and quality of green infrastructure (GI), which provides essential ecosystem services that enhance well-being.
Adedotun Dipeolu
doaj +1 more source
Substituent Effects in Ugi–Smiles Reactions
, 2016 In a recent communication, we described the mechanism of the well-known Ugi-type reactions with a model system (J. Org. Chem. 2012, 77, 1361−1366). Herein, focusing on the Ugi–Smiles coupling, we study the effects of each of the four reactants on the ...
Laurence Grimaud (1921282) +4 more
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, 2016 The Ugi coupling reaction involves the combination of isocyanide (a), aldehyde (b), amine (c) and carboxylic acid (d) components in a single reaction step to give an α-aminoacyl amide product, as exemplified above for the preparation of AZ126.
Darren S. Heeke (3220149) +13 more
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N–N bond formation in Ugi processes: from nitric acid to libraries of nitramines
, 2017 International audienceThe Ugi reaction has drawn considerable attention over the years leading to numerous libraries of heterocycles and various extensions changing the nature of the components of the coupling.
Mercalli, Valentina +5 more
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How urban green infrastructure contributes to carbon neutrality
Buildings & CitiesReaching the carbon-neutrality targets of cities necessitates not only reducing emissions but also enhancing carbon sinks. This is enabled by urban green infrastructure (UGI), which is a cost-effective sink that provides numerous co-benefits beyond ...
Ranja Hautamäki +3 more
doaj +1 more source
Synthesis of novel boron-containing Ugi analogues and their biological evaluations
, 2014 碩士在傳統的藥物開發中，含硼分子顯少被列入考慮。但近來研究發現含硼藥物分子對其所作用之生化目標具有高度選擇性與高度活性等優點，使許多研究單位逐漸積極投入含硼藥物之開發，除了已經市售之硼酸抗癌藥物Bortezomib(VelcadeTM)外，目前也有愈來愈多的含硼化合物進入FDA之臨床測試階段，證明了含硼藥物的開發是一個非常值得注意的新領域。 本研究利用Ugi多組成反應(Ugi-4CR)於簡單的反應條件下合成硼酸與硼酯之Ugi化合物(Scheme 1)，其是以Methanol作為反應溶劑 ...
連汝卿; Lian, Ru-Ching
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