Results 151 to 160 of about 2,043,921 (203)

A Three-Layer Transformation Strategy toward Functionalized Fused Hydantoins and Diketopiperazines. [PDF]

Org Lett
Giannakaki MA, Zingiridis M, Froudas KG, Neochoritis CG.   +3 more
europepmc   +1 more source

A First Diversity-Oriented <i>N</i>-Maleopimarimido-Isocyanide for Multicomponent Reactions: Synthesis, Application, and In Silico Evaluation. [PDF]

Int J Mol Sci
Tretyakova E, Smirnova A, Kazakova O.
europepmc   +1 more source

1,5-Disubstituted Tetrazoles as Promising Anticancer Resistance Agents: A Chemoinformatic Characterization. [PDF]

ACS Omega
Garibay-Manríquez C, Díaz-Cervantes E, Chacón-García L, Martinez-Mayorga K, Cortés-García CJ.   +4 more
europepmc   +1 more source

Repeat region engineering of Cas13a crRNA enables conformational gating-based autocatalytic CRISPR biosensing. [PDF]

Nucleic Acids Res
Ding W, Yang X, Yang Y, Liu M, Liu C, Wang J, Liu X.   +6 more
europepmc   +1 more source

Ugi-Tetrazole-Derived α‑Aminomethyl Scaffolds Reveal Unexpected Binding Modes in SARS-CoV‑2 3CLpro. [PDF]

ACS Med Chem Lett
van der Straat R, Oerlemans R, Cong Y, Boxma J, Bulai RG, Río-Bergé C, Koekemoer L, Zarganes Tzitzikas T, Guan Z, Marples PG, Reggiori F, Groves M, Dömling A.   +12 more
europepmc   +1 more source

A Single-Enzyme Activated CRISPR-Cas12a Nano System via Subtly Balanced dsDNA for Kinetic-Gated UDG Detection and Spatiotemporal Cellular Imaging. [PDF]

Adv Sci (Weinh)
Dong K, Hu H, Wang H, Zheng Z, Cheng S, Shu W, Liu R, Xin X, Huang S, Qian D, Xiao X, Fu Q, Wang H.   +12 more
europepmc   +1 more source

Thymidylate synthase inhibitory drugs induce p53-dependent pathways differently. [PDF]

PLoS One
Holub E, Szajkó MB, Felföldi A, Vértessy BG, Békési A.   +4 more
europepmc   +1 more source

Ugi multicomponent reactions of optically active aldehydes and chiral aminoindanols: diastereoselective synthesis of bisamides relevant to SARS-CoV-2 Mpro inhibitors.

Org Biomol Chem
Ghosh AK, Bhattacharjee A, Jayashankar U, Bogan SN, Mesecar AD.   +4 more
europepmc   +1 more source

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An Ugi Reaction in the Total Synthesis of (−)‐Dysibetaine

Angewandte Chemie - International Edition, 2009
AbstractEinen einfachen Zugang zu (−)‐Dysibetain bietet eine elfstufige Reaktion ausgehend von L‐Äpfelsäure (siehe Schema). Der Schlüsselschritt ist eine einzigartige Vier‐Zentren‐drei‐Komponenten‐Ugi‐Cyclisierung, bei der eine Estereinheit als Carbonsäurekomponente fungiert.
Yoshihisa Kobayashi
exaly   +3 more sources