Results 121 to 130 of about 12,153 (191)

Impact of <i>UGT1A1*28</i> polymorphism in patients with metastatic pancreatic ductal adenocarcinoma treated with NALIRIFOX in the NAPOLI 3 trial. [PDF]

Future Oncol
Abdelrahim M, Khan G, Hatoum H, Zervoudakis A, Dayyani F, Zhang L, Li J, Maxwell F, O'Reilly EM, Wainberg ZA, Bullock A.   +10 more
europepmc   +1 more source

Analysis of UGT1A1 germline variants in patients with advanced breast cancer treated with trastuzumab-deruxtecan: results from the PROCURE Project. [PDF]

ESMO Open
Sánchez-Bayona R, de Nicolás-Hernández J, Saura C, Gion M, Cejalvo JM, Llabrés E, Cortés J, Falcón A, Pernas S, López de Sa A, Vidal M, Hinojo C, Curiel T, Cruz J, Martínez V, Cantos B, Echarri MJ, Gallegos I, Bueno C, Vargas AM, Escrivá-de-Romaní S, Fullana B, Cobos MA, Arenas A, Joval-Ramentol L, Ortiz P, Pascual T, Valdivia C, Villacampa G, Ciruelos E, Rodriguez-Antona C.   +30 more
europepmc   +1 more source

Sacituzumab govitecan in Japanese participants with HR+/HER2- metastatic breast cancer: primary results from the phase II ASCENT-J02 study. [PDF]

Jpn J Clin Oncol
Shimomura A, Kogawa T, Matsumoto K, Watanabe J, Watanabe K, Nakayama T, Shien T, Iwasa T, Padman S, Huynh D, Shao J, Kwan J, Iwahori Y, Naito Y, Iwata H.   +14 more
europepmc   +1 more source

First-In-Human Evaluation of the Pharmacokinetics, Pharmacodynamics, and Safety of Tilpisertib Fosmecarbil (GS-5290), an Oral Prodrug of a Tumor Progression Locus 2 Inhibitor in Healthy Participants. [PDF]

J Clin Pharmacol
Madia PA, Wendt ER, Qin AR, Qi X, Liang Y, Kalariya S, Hong F, Canales E, Taylor JG, Arulmani U, Kakkar T.   +10 more
europepmc   +1 more source

Concentration dependency of an acyl glucuronide metabolite in eltrombopag-induced hepatotoxicity: Role of UGT1A1 genotype. [PDF]

Br J Clin Pharmacol
Oda S, Doki K, Obara N, Suzuki Y, Sakata-Yanagimoto M, Homma M.   +5 more
europepmc   +1 more source

Development of an adult whole-body PBPK model of irinotecan and its metabolites for predicting UGT1A1/CYP3A-mediated drug-drug interactions. [PDF]

Front Pharmacol
Chen B, Li L, Xu W, Xu H, Zhu X, He Q, Zhu X, Chi-Lui Ho P, Xiang X, Ji P.   +9 more
europepmc   +1 more source

Genetic, clinical, and biochemical profiling of Gilbert syndrome in a Nepali cohort: High prevalence of the UGT1A1 c.-3279T>G polymorphism and correlation with hematological parameters. [PDF]

PLoS One
Ghimire PG, Ghimire P, Pande R.
europepmc   +1 more source

Determinants of HIV-1 virologic suppression in HIV-associated tuberculosis in Brazil. [PDF]

Mem Inst Oswaldo Cruz
Ridolfi F, Amorim G, Haas DW, Arriaga M, Staats C, Cordeiro-Santos M, Kritski AL, Figueiredo MC, Andrade BB, Sterling TR, Rolla VC, Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil Consortium, Benjamin A, Sant'Anna FM, Oliveira JG, Marin J, Rezende A, Carvalho AC, Rocha M, Nogueira B, Brito A, Spener R, Turner M.   +22 more
europepmc   +1 more source

Genotyping of DPYD and UGT1A1 in Brazilian oncological patients: applying pharmacogenomics in an admixed population. [PDF]

Rev Assoc Med Bras (1992)
Cereser VHB, Moniz CMV, Suarez-Kurtz G, Estevez-Diz MDP.   +3 more
europepmc   +1 more source