Results 111 to 120 of about 12,153 (191)

The Dual Role of Human UDP-Glucuronosyltransferase-Mediated Metabolism in Tumor Drug Resistance: Mechanisms and Prospects. [PDF]

Int J Mol Sci
Wang Z, Zhong J, Ren C, Shi H, Fang X, Xiao X, Liu X, Cao D, Zeng X.   +8 more
europepmc   +1 more source

Uridine diphosphate glucuronosyltransferase 1A1 gene polymorphisms and treatment outcomes in HIV and MTB coinfection in sub-Saharan Africa: a scoping review protocol. [PDF]

BMJ Open
Vhanda D, Musarurwa C, Chikwati RP, Muziringa M, Dandara C, Manasa J, Chirenda J, Mavenyengwa RT.   +7 more
europepmc   +1 more source

Fraxetin Inhibits UGT1A1 and UGT1A9 Activities In Vitro: Inhibition Kinetics, Molecular Dynamics Simulation, and Prediction of Herb-Drug Interaction Risk. [PDF]

Pharmaceuticals (Basel)
Chen J, Han H, Li J, Xu S, Li X, Zhao Z.
europepmc   +1 more source

Case Report: Persistent indirect hyperbilirubinemia caused by Gilbert syndrome misdiagnosed as drug-induced liver injury during tuberculosis treatment. [PDF]

Front Med (Lausanne)
Liu P, Xu Y.
europepmc   +1 more source

Computational analysis and validation of UGT1A1/4 missense variants impacting tecovirimat metabolism in monkeypox patients. [PDF]

Front Syst Biol
Abdelazim AA, Hassanein SE, Maged M, Al-Theyab NS, Kimiko I, Attia KA.   +5 more
europepmc   +1 more source

Unveiling the role of UGT enzymes in chemoresistance: a path to enhanced cancer pharmacotherapy. [PDF]

Cancer Drug Resist
Kretzschmar G, Budagaga Y, Groß L, Küpper JH, Kammerer S, Hofman J.   +5 more
europepmc   +1 more source

UGT1A1*28 Allele Negative [PDF]

, 2020
openaire   +1 more source

DPYD and UGT1A1 Genotype-Based Dosing for Fluoropyrimidines and Irinotecan Chemotherapy: Variant-Specific Impact on Treatment Intensity and Toxicity. [PDF]

Int J Cancer
Gambron M, Peruzzi E, Perfler S, Montico M, Cecchin R, De Mattia E, Spina M, Lisanti C, Corsetti S, Foltran L, Puglisi F, Roncato R, Cecchin E.   +12 more
europepmc   +1 more source

The Impact of <i>UGT1A1</i> Genetic Variability on Enzyme Expression in Liver Pathology. [PDF]

Genes (Basel)
Szeląg-Pieniek S, Kucak J, Malinowski D, Oswald S, Droździk M, Kurzawski M.   +5 more
europepmc   +1 more source

Model-based clinical utility of pharmacogenetic testing and its potential population impact on the use of essential medicines in Zimbabwe. [PDF]

Front Pharmacol
Mazhindu TA, Chikwambi Z, Grimes KV, Borok MZ, Ndlovu N, Masimirembwa C.   +5 more
europepmc   +1 more source