Results 211 to 220 of about 17,886 (241)

Mass Spectrometry Imaging Combined With Single‐Cell Transcriptional Profiling Reveals the Multidimensional Spatial Distributions and Biosynthetic Pathways of Medicinal Components in Andrographis paniculata

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT The synthesis and accumulation of active ingredients in medicinal plants are distributed in specific organs, tissues, and cell types, which are important for the exploitation of medicinal plants. However, the fine distribution of active ingredients is difficult to know. Here, the system of mass spectrometry imaging (MSI) integrated with single‐
HaiSheng Zeng   +14 more
wiley   +1 more source

Chromosome‐Level Genome Assembly of the Allotetraploid Gynostemma pentaphyllum Provides Novel Insights Into the Biosynthesis of Ginsenoside and Gypenoside LVI

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Gynostemma pentaphyllum, a herb used in tea and traditional Chinese medicine, shows geographic variation in its production of valuable dammarane‐type ginsenosides and gypenoside LVI between populations from Suining (SN) and Nanning (NN). To elucidate the mechanisms underlying this differential metabolite accumulation, a chromosome‐level genome
Peina Zhou   +12 more
wiley   +1 more source

Distinct Defence Mechanisms of Allelopathic Rice Against Quinclorac‐Susceptible and ‐Resistant Barnyardgrass: Involvement of Specific Metabolites and Rhizosheath Microbiota

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Allelopathic rice is increasingly recognised as a promising strategy for sustainable weed management. Resistance to the herbicide quinclorac is widespread in barnyardgrass, but it remains unclear whether allelopathic rice exerts the same defence against herbicide‐susceptible and ‐resistant barnyardgrass. We conducted integrated transcriptomic,
Shuyan Li   +5 more
wiley   +1 more source

The ontogeny of hepatic cytochrome P450 enzymes in conventional pigs using enzyme activity and proteomics [PDF]

open access: yes, 2017
Croubels, Siska   +5 more
core   +1 more source

Improved Performance of UHPLC–MS Hyphenated Systems

LCGC North America, 2022
An ultrahigh-pressure liquid chromatography–mass spectrometry (UHPLC–MS) research prototype instrument was built to improve the resolution power and the usability of conventional LC–MS hyphenated instruments for routine analyses in pharmaceutical applications.
Fabrice G. Gritti   +3 more
openaire   +1 more source

Profiling of illicit fentanyl using UHPLC–MS/MS

Forensic Science International, 2012
Methodology is presented for the profiling of fentanyl in seized drugs using ultra high performance liquid chromatography in combination with tandem mass spectrometry (UHPLC-MS/MS). Target analysis was performed for 40 fentanyl processing impurities, several of which are markers for a specific synthetic route (Siegfried or Janssen).
Ira S, Lurie   +4 more
openaire   +2 more sources

Integrative metabolic profile of myelodysplastic syndrome based on UHPLC–MS

Biomedical Chromatography, 2021
AbstractMyelodysplastic syndrome (MDS) is a neoplastic disease originating from hematopoietic stem cells. Currently, hematopoietic stem cell transplantation (HSCT) is the most effective cure, although lenalidomide, azacytidine, and decitabine have been applied to relieve symptoms of MDS.
Yunxia Yuan   +7 more
openaire   +2 more sources

Quantitative Analysis of Bile Acid with UHPLC-MS/MS

2020
Bile acids are important end products of cholesterol metabolism, having been shown to serve as signaling molecules and intermediates between the host and the gut microbiota. Here we describe a robust and accurate method using ultrahigh-pressure liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS) for the quantification of bile ...
Yuan, Tian   +4 more
openaire   +2 more sources

Study of Sangiovese Wines Pigment Profile by UHPLC-MS/MS

Journal of Agricultural and Food Chemistry, 2012
The metabolic pigment composition of Sangiovese wines produced from grapes harvested at 20 different vineyards in Montalcino over three consecutive years (2008-2010) on a semi-industrial scale and of 55 commercial Brunello di Montalcino wines (2004-2007) was studied, using a targeted method capable of analyzing 90 pigments in an 11 min UHPLC-MS/MS ...
Arapitsas, Panagiotis   +3 more
openaire   +3 more sources

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