Results 21 to 30 of about 7,704,969 (300)

UK Biobank : an Open Access resource for identifying the causes of a wide range of complex diseases of middle and old age [PDF]

open access: yes, 2015
• UK Biobank is a very large and detailed prospective study with over 500,000 participants aged 40–69 years when recruited in 2006–2010. • The study has collected and continues to collect extensive phenotypic and genotypic detail about its ...
Landray, Martin   +123 more
core   +1 more source

A frailty index for UK Biobank participants [PDF]

open access: yesThe Journals of Gerontology: Series A, 2017
Abstract Background Frailty indices (FIs) measure variation in health between aging individuals. Researching FIs in resources with large-scale genetic and phenotypic data will provide insights into the causes and consequences of frailty. Thus, we aimed to develop an FI using UK Biobank data, a cohort
Dylan M Williams   +3 more
openaire   +2 more sources

Genetic stratification of depression in UK Biobank [PDF]

open access: yesTranslational Psychiatry, 2020
AbstractDepression is a common and clinically heterogeneous mental health disorder that is frequently comorbid with other diseases and conditions. Stratification of depression may align sub-diagnoses more closely with their underling aetiology and provide more tractable targets for research and effective treatment. In the current study, we investigated
David M. Howard   +15 more
openaire   +7 more sources

Characterisation of liver fat in the UK Biobank cohort [PDF]

open access: yes, 2017
Non-alcoholic fatty liver disease and the risk of progression to steatohepatitis, cirrhosis and hepatocellular carcinoma have been identified as major public health concerns. We have demonstrated the feasibility and potential value of measuring liver fat
Garratt, S.   +10 more
core   +1 more source

The association of alcohol consumption with glaucoma and related traits : findings from the UK Biobank

open access: yes, 2022
PURPOSE: To examine the associations of alcohol consumption with glaucoma and related traits; to assess whether a genetic predisposition to glaucoma modified these associations; and to perform Mendelian randomization (MR) experiments to probe causal ...
Sun, Zihan,   +34 more
core   +1 more source

UK Biobank Kinetic Energy Harvesting

open access: yes, 2022
Software for processing the UK Biobank accelerometer datasets in the paper 'Estimation of kinetic energy harvesting potential for self-powered wearable devices with 67,000 participants from the UK ...
Christopher Beach (9999347)   +1 more
core   +2 more sources

Two separate, large cohorts reveal potential modifiers of age-associated variation in visual reaction time performance

open access: yesnpj Aging and Mechanisms of Disease, 2021
To identify potential factors influencing age-related cognitive decline and disease, we created MindCrowd. MindCrowd is a cross-sectional web-based assessment of simple visual (sv) reaction time (RT) and paired-associate learning (PAL).
J. S. Talboom   +17 more
doaj   +1 more source

Algorithms for the Capture and Adjudication of Prevalent and Incident Diabetes in UK Biobank.

open access: yesPLoS ONE, 2016
ObjectivesUK Biobank is a UK-wide cohort of 502,655 people aged 40-69, recruited from National Health Service registrants between 2006-10, with healthcare data linkage. Type 2 diabetes is a key exposure and outcome.
Sophie V Eastwood   +8 more
doaj   +1 more source

Association of the transthyretin variant V122I with polyneuropathy among individuals of African ancestry

open access: yesScientific Reports, 2021
Hereditary transthyretin-mediated (hATTR) amyloidosis is an underdiagnosed, progressively debilitating disease caused by mutations in the transthyretin (TTR) gene.
Margaret M. Parker   +21 more
doaj   +1 more source

Harmonization of Biobank Education for Biobank Technicians: Identification of Learning Objectives

open access: yes, 2022
The quality of biospecimens stored in a biobank depends tremendously on the technical personnel responsible for processing, storage, and release of biospecimens.
Winter, Theresa; Integrated Research Biobank, University Medicine Greifswald, 17475 Greifswald, Germany, theresa.winter@med.uni-greifswald.de   +15 more
core   +1 more source

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