Results 21 to 30 of about 8,179,520 (254)

The landscape of health disparities in the UK Biobank

Database, 2023
Abstract The UK Biobank (UKB), a large-scale biomedical database that includes demographic and electronic health record data for more than half a million ethnically diverse participants, is a potentially valuable resource for the study of health disparities.
Shashwat Deepali Nagar, I. King Jordan, Leonardo Mariño-Ramírez   +2 more
openaire   +3 more sources

A frailty index for UK Biobank participants [PDF]

The Journals of Gerontology: Series A, 2017
Abstract Background Frailty indices (FIs) measure variation in health between aging individuals. Researching FIs in resources with large-scale genetic and phenotypic data will provide insights into the causes and consequences of frailty. Thus, we aimed to develop an FI using UK Biobank data, a cohort
Dylan M Williams, Juulia Jylhävä, Nancy L Pedersen, Sara Hägg   +3 more
openaire   +2 more sources

UK Biobank demographic information.

, 2022
UK Biobank demographic information.
Chris Zajner (14253213), Vaibhav Sharma (11085561), Judes Poirier (1779919), AmanPreet Badhwar (768519), Sylvia Villeneuve (418760), Karin Saltoun (14253207), Sarah A. Gagliano Taliun (6836708), Chloé Savignac (14253204), Sali Farhan (6594914), Danilo Bzdok (333738), Kimia Shafighi (14253210)   +10 more
core   +1 more source

UK Biobank : an Open Access resource for identifying the causes of a wide range of complex diseases of middle and old age [PDF]

, 2015
• UK Biobank is a very large and detailed prospective study with over 500,000 participants aged 40–69 years when recruited in 2006–2010. • The study has collected and continues to collect extensive phenotypic and genotypic detail about its ...
Landray, Martin, Young A, Sudlow Cathie, Landray M, Danesh, J, Ong, G, Elliott Paul, Ong, Giok J., Burton Paul, Peakman, Tim, Sprosen, Tim, Paul Downey, Tim Peakman, Paul Matthews (5293), Burton, P, Danesh John, Paul Downey (715514), Matthews P, John Danesh, Matthews, P, Giok Ong (715517), Ong Giok, Elliott, Paul, Pell, Jill, Allen Naomi, Bette Liu (369430), Tim Sprosen (715520), Downey Paul, Landray, M, Gallacher, John Edward, Cathie Sudlow, Paul Matthews, Elliott, P, Beral Valerie, Naomi Allen (140094), Tim Sprosen, Burton, Paul R., Paul Elliott, Young Alan, Rory Collins (17972), Downey P, Young, A, Jill Pell (715518), Peakman T, Danesh, John, Silman, Alan J., Martin Landray, Cathie Sudlow (259959), Ong, Giok, Alan Young (348048), Tim Peakman (715521), Sudlow, Cathie; id_orcid, Allen, Naomi E., Allen, N, Alan Silman, Gallacher John, Green J, Landray Martin, Landray, Martin J., Paul Burton (288048), Green Jane, Allen N, Pell J, Liu, B, Alan Silman (715519), Sprosen T, Pell Jill, Allen, Naomi, Green, Jane, Green, J, Gallacher, John, Elliott P, John Gallacher, Peakman, T, Matthews, Paul, Pell, J, Collins Rory, Sudlow C, Liu, B ; https://orcid.org/, Valerie Beral, John Gallacher (196569), Burton P, Silman Alan, Bette Liu, Sprosen, T, Liu Bette, Silman, Alan, Matthews Paul, Rory Collins, Beral V, Giok Ong, Sudlow, C, Naomi Allen, Beral, V, Collins, Rory, Sprosen Tim, Beral, V. (Valerie), John Danesh (8874), Collins, R, Jill Pell, Paul Burton, Paul Elliott (27295), Danesh J, Gallacher J, Downey, Paul, Sudlow, Cathie, Jane Green (715515), Young, Alan, Silman, A, Gallacher, J, Ong G, Burton, Paul, Collins R, Jane Green, Alan Young, Valerie Beral (54657), Silman A, Liu, Bette, Downey, P, Martin Landray (715516), Beral, Valerie, Liu B, Peakman Tim   +122 more
core   +1 more source

Genetic stratification of depression in UK Biobank [PDF]

Translational Psychiatry, 2020
AbstractDepression is a common and clinically heterogeneous mental health disorder that is frequently comorbid with other diseases and conditions. Stratification of depression may align sub-diagnoses more closely with their underling aetiology and provide more tractable targets for research and effective treatment. In the current study, we investigated
David M. Howard, Lasse Folkersen, Jonathan R. I. Coleman, Mark J. Adams, Kylie Glanville, Thomas Werge, Saskia P. Hagenaars, Buhm Han, David Porteous, Archie Campbell, Toni-Kim Clarke, Gerome Breen, Patrick F. Sullivan, Naomi R. Wray, Cathryn M. Lewis, Andrew M. McIntosh   +15 more
openaire   +7 more sources

Summary demographics of UK Biobank.

, 2021
Summary demographics of UK Biobank.
Sean Harrison (1906282), Alisha R. Davies (10977303), Padraig Dixon (4533463), Neil M. Davies (11349398), Laura D. Howe (7246277), Hayley E. Jones (7734650)   +5 more
core   +1 more source

Algorithms for the Capture and Adjudication of Prevalent and Incident Diabetes in UK Biobank.

PLoS ONE, 2016
ObjectivesUK Biobank is a UK-wide cohort of 502,655 people aged 40-69, recruited from National Health Service registrants between 2006-10, with healthcare data linkage. Type 2 diabetes is a key exposure and outcome.
Sophie V Eastwood, Rohini Mathur, Mark Atkinson, Sinead Brophy, Cathie Sudlow, Robin Flaig, Simon de Lusignan, Naomi Allen, Nishi Chaturvedi   +8 more
doaj   +1 more source

Association of the transthyretin variant V122I with polyneuropathy among individuals of African ancestry

Scientific Reports, 2021
Hereditary transthyretin-mediated (hATTR) amyloidosis is an underdiagnosed, progressively debilitating disease caused by mutations in the transthyretin (TTR) gene.
Margaret M. Parker, Scott M. Damrauer, Catherine Tcheandjieu, David Erbe, Emre Aldinc, Philip N. Hawkins, Julian D. Gillmore, Leland E. Hull, Julie A. Lynch, Jacob Joseph, Simina Ticau, Alexander O. Flynn-Carroll, Aimee M. Deaton, Lucas D. Ward, Themistocles L. Assimes, Philip S. Tsao, Kyong-Mi Chang, Daniel J. Rader, Kevin Fitzgerald, Akshay K. Vaishnaw, Gregory Hinkle, Paul Nioi   +21 more
doaj   +1 more source

Characterisation of liver fat in the UK Biobank cohort [PDF]

, 2017
Non-alcoholic fatty liver disease and the risk of progression to steatohepatitis, cirrhosis and hepatocellular carcinoma have been identified as major public health concerns. We have demonstrated the feasibility and potential value of measuring liver fat
Garratt, S., Neubauer, S, Matthews, P., Milanesi, M., Thomas, E.L., Gyngell, M, Kelly, M., Bell, J.D., Herlihy, A.H., Banerjee, R, Wilman, H.   +10 more
core   +1 more source

Education is power: preserving cognition in the UK biobank

Frontiers in Public Health, 2023
IntroductionDementia is a debilitating syndrome characterized by the gradual loss of memory and cognitive function. Although there are currently limited, largely symptomatic treatments for the diseases that can lead to dementia, its onset may be prevented by identifying and modifying relevant life style risk factors.
Benjamin Tari, Morgane Künzi, Morgane Künzi, C. Patrick Pflanz, Vanessa Raymont, Sarah Bauermeister   +5 more
openaire   +3 more sources