Results 21 to 30 of about 121,766 (195)
npj Aging and Mechanisms of Disease, 2021 To identify potential factors influencing age-related cognitive decline and disease, we created MindCrowd. MindCrowd is a cross-sectional web-based assessment of simple visual (sv) reaction time (RT) and paired-associate learning (PAL).
J. S. Talboom +17 more
doaj +1 more source
Monocular and binocular visual impairment in the UK Biobank study: prevalence, associations and diagnoses [PDF]
, 2018 Objective; To determine the prevalence of, associations with and diagnoses leading to mild visual impairment or worse (logMAR >0.3) in middle-aged adults in the UK Biobank study.
Chou +7 more
core +1 more source
A frailty index for UK Biobank participants [PDF]
The Journals of Gerontology: Series A, 2017 AbstractBackgroundFrailty indices (FIs) measure variation in health between aging individuals. Researching FIs in resources with large-scale genetic and phenotypic data will provide insights into the causes and consequences of frailty. Thus, we aimed to develop an FI using UK Biobank data, a cohort study of 500,000 middle-aged and older adults ...
Dylan M Williams +3 more
openaire +2 more sources
Genetic stratification of depression in UK Biobank [PDF]
Translational Psychiatry, 2020 AbstractDepression is a common and clinically heterogeneous mental health disorder that is frequently comorbid with other diseases and conditions. Stratification of depression may align sub-diagnoses more closely with their underling aetiology and provide more tractable targets for research and effective treatment. In the current study, we investigated
David M. Howard +15 more
openaire +5 more sources
Polygenic risk for schizophrenia and season of birth within the UK Biobank cohort [PDF]
, 2018 Background: There is strong evidence that people born in winter and in spring have a small increased risk of schizophrenia. As this ‘season of birth’ effect underpins some of the most influential hypotheses concerning potentially modifiable risk ...
Escott-Price, Valentina +7 more
core +3 more sources
Nature Communications, 2020 Accurately measuring genetic relatedness by Identical-By-Descent (IBD) segments is challenging in biobank-level genome data. The authors present IBD method FastSMC, which when applied to the UK Biobank gives a detailed picture of genetic relatedness and ...
Juba Nait Saada +6 more
doaj +1 more source
Scientific Reports, 2021 Hereditary transthyretin-mediated (hATTR) amyloidosis is an underdiagnosed, progressively debilitating disease caused by mutations in the transthyretin (TTR) gene.
Margaret M. Parker +21 more
doaj +1 more source
Managing Access to Biobanks:How Can We Reconcile Privacy and Public Interests in Genetic Research? [PDF]
, 2010 This article is concerned with the ultimate objectives of genetic biobanks set up to promote the public interest—being the sharing of samples and data for medical research—and the consequences for personal privacy of realising them.
Frenkel, D. A. +7 more
core +1 more source
ACR Open Rheumatology, 2021 Objectives The objectives for this study were to assess whether gout and/or rheumatoid arthritis (RA) are risk factors for coronavirus disease 2019 (COVID‐19) diagnosis and to assess whether gout and/or RA are risk factors for death from COVID‐19 ...
Ruth K. Topless +6 more
doaj +1 more source
Frontiers in Endocrinology, 2023 IntroductionNonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) are both chronic multisystem diseases that cause tremendous health burdens worldwide.
Yuetian Yu +6 more
doaj +1 more source