Results 41 to 50 of about 61,679 (166)
Frontiers in Cardiovascular Medicine, 2020 Large population studies such as the UK Biobank provide great opportunities for understanding the pathophysiology, health impact and prognostic factors associated with COVID-19, a condition that has had significant impact on almost everyone around the ...
Mohammed Y. Khanji +8 more
doaj +1 more source
International Journal of Population Data Science, 2022 Objectives COVID-19 disproportionately affects older patients with pre-existing health conditions. However at the time of writing, June 2021, the relationship between COVID-19, ethnicity and deprivation is unclear.
Deborah Allen +2 more
doaj +1 more source
UK Biobank Data: Come and Get It
Science Translational Medicine, 2014 UK Biobank invites scientists to make use of the vast (and growing) amounts of data in this open-access resource for public health research.
Allen, N +3 more
openaire +3 more sources
BMC Public HealthBackground Malnutrition is a complication of chronic kidney disease (CKD). Whether malnutrition, assessed via the geriatric nutritional risk index (GNRI), is associated with the incidence and risk of CKD in older individuals remains unclear. Methods Data
Peilin Zou +7 more
doaj +1 more source
Enhancing dementia diagnosis data in UK Biobank: the UK Biobank Brain Health Study [PDF]
Alzheimers DementAbstract Background As the UK Biobank population of half a million participants enters older age (current mean age 73 years), the number of dementia cases in the cohort is rapidly increasing. At present, individuals living with dementia can be identified through linkage to electronic hospital ...
Maccora J +8 more
europepmc +3 more sources
PLoS ONE, 2015 ObjectiveWe performed a systematic review of the accuracy of patient self-report of stroke to inform approaches to ascertaining and confirming stroke cases in large prospective studies.MethodsWe sought studies comparing patient self-report against a ...
Rebecca Woodfield +3 more
doaj +1 more source
Sex differences in genetic architecture in the UK Biobank
Nature Genetics, 2021 Males and females present differences in complex traits and in the risk of a wide array of diseases. Genotype by sex (GxS) interactions are thought to account for some of these differences. However, the extent and basis of GxS are poorly understood. In the present study, we provide insights into both the scope and the mechanism of GxS across the genome
Elena Bernabeu +5 more
openaire +3 more sources
EClinicalMedicine, 2022 Summary: Background: Serum lipid traits are associated with cardiovascular disease, but uncertainty remains regarding their associations with dementia. Methods: From 2006 to 2010, 254,575 women and 214,891 men were included from the UK Biobank.
Jessica Gong +3 more
doaj +1 more source
Evidence in the UK Biobank for the underdiagnosis of erythropoietic protoporphyria
Genetics in Medicine, 2021 Erythropoietic protoporphyria (EPP), characterized by painful cutaneous photosensitivity, results from pathogenic variants in ferrochelatase (FECH). For 96% of patients, EPP results from coinheriting a rare pathogenic variant in trans of a common hypomorphic variant c.315-48T>C (minor allele frequency 0.05). The estimated prevalence of EPP derived from
Amy K. Dickey +17 more
openaire +5 more sources
Confound modelling in UK Biobank brain imaging
NeuroImage, 2020 Abstract Dealing with confounds is an essential step in large cohort studies to address problems such as unexplained variance and spurious correlations. UK Biobank is a powerful resource for studying associations between imaging and nonimaging measures such as lifestyle factors and health outcomes, in part because of the large subject ...
Fidel Alfaro-Almagro +7 more
openaire +5 more sources