Results 31 to 40 of about 7,704,969 (300)
Autistic traits in the UK Biobank
Abstract This study describes the profile of more than 139,000 participants who completed the Autism-Spectrum Quotient (AQ) in the UK Biobank, and tests whether the AQ’s key findings replicate in the largest sample to date of people who have completed the full 50-item version of the measure.
Fysh M +10 more
europepmc +3 more sources
ACR Open Rheumatology, 2021 Objectives The objectives for this study were to assess whether gout and/or rheumatoid arthritis (RA) are risk factors for coronavirus disease 2019 (COVID‐19) diagnosis and to assess whether gout and/or RA are risk factors for death from COVID‐19 ...
Ruth K. Topless +6 more
doaj +1 more source
Frontiers in Endocrinology, 2023 IntroductionNonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) are both chronic multisystem diseases that cause tremendous health burdens worldwide.
Yuetian Yu +6 more
doaj +1 more source
Education is power: preserving cognition in the UK biobank
Frontiers in Public Health, 2023 IntroductionDementia is a debilitating syndrome characterized by the gradual loss of memory and cognitive function. Although there are currently limited, largely symptomatic treatments for the diseases that can lead to dementia, its onset may be prevented by identifying and modifying relevant life style risk factors.
Benjamin Tari +5 more
openaire +3 more sources
Identification and validation of myocardial infarction and stroke outcomes at scale in UK Biobank
International Journal of Population Data Science, 2017 Aims We aimed (i) to create algorithms for identifying stroke and acute myocardial infarction (MI) cases in a large prospective population-based study (UK Biobank), using linked data from national hospital admissions data and death registers, combined ...
Christian Schnier +8 more
doaj +1 more source
Epidemiology of Cholesteatoma in the UK Biobank [PDF]
Clinical OtolaryngologyLevel of Evidence: 3 Objective(s) To identify the risk factors for Cholesteatoma in a large UK cohort. Although some risk factors are well established (male sex, history of chronic otitis media), others require further evidence (deprivation, smoking). Design and Setting
Emma Wilson +5 more
openaire +3 more sources
An atlas of genetic associations in UK Biobank [PDF]
Nature Genetics, 2017 ABSTRACT Genome-wide association studies have revealed many loci contributing to the variation of complex traits, yet the majority of loci that contribute to the heritability of complex traits remain elusive. Large study populations with sufficient statistical power are required to detect the small effect sizes of the
Oriol Canela-Xandri +2 more
openaire +4 more sources
Comorbidities and ethnic health disparities in the UK biobank
JAMIA Open, 2022 AbstractObjectiveThe goal of this study was to investigate the relationship between comorbidities and ethnic health disparities in a diverse, cosmopolitan population.Materials and MethodsWe used the UK Biobank (UKB), a large progressive cohort study of the UK population.
Whitney L Teagle +5 more
openaire +3 more sources
Nature Communications, 2020 Between 2014 and 2023, 100,000 UK Biobank participants are undergoing brain, heart and abdominal MRI, as well as DXA and carotid ultrasound scans. In this review, authors provide a detailed overview of the rationale for the collection of these imaging ...
Thomas J. Littlejohns +23 more
doaj +1 more source
Overestimated prediction using polygenic prediction derived from summary statistics
BMC Genomic Data, 2023 Background When polygenic risk score (PRS) is derived from summary statistics, independence between discovery and test sets cannot be monitored. We compared two types of PRS studies derived from raw genetic data (denoted as rPRS) and the summary ...
David Keetae Park +8 more
doaj +1 more source