Results 271 to 280 of about 524,302 (394)

Ruxolitinib and vedolizumab salvage therapy in the setting of cytomegalovirus colitis for a patient with newly diagnosed very early onset inflammatory bowel disease

open access: yesJPGN Reports, EarlyView.
Abstract Acute severe ulcerative colitis increases the risk for cytomegalovirus (CMV) infection, particularly with the use of immunocompromising medications. We report a case of a 4‐year‐old with newly diagnosed very early onset inflammatory bowel disease presenting with acute severe colitis refractory to both corticosteroids and infliximab, whose ...
Alison Laxer   +3 more
wiley   +1 more source

Frequency and impact of repeat colonoscopy as a treat‐to‐target approach in pediatric inflammatory bowel disease

open access: yesJPGN Reports, EarlyView.
Abstract Objectives Endoscopic healing (EH) is a treatment target in inflammatory bowel disease (IBD). However, adherence to repeat colonoscopy (RC) for EH assessment in pediatrics remains variable. We aimed to evaluate the frequency and timing of RC after diagnosis and its impact on treatment decisions at a large pediatric IBD center.
Kari Noel VanEvery   +5 more
wiley   +1 more source

Impact of timing on mucosal healing during restaging endoscopy in pediatric Crohn's disease: A retrospective cohort study

open access: yesJPGN Reports, EarlyView.
Abstract While endoscopic remission is an important target in pediatric Crohn's disease (CD), no consensus for restaging timing exists. This retrospective cohort study assessed the timing and impact of restaging endoscopy in children with new CD in remission, comparing earlier ( ≤ 9 months) versus later endoscopy.
Anna Janecek   +7 more
wiley   +1 more source

Muscular and serosal eosinophilic gastritis and enteritis with eosinophilic ascites successfully treated with dupilumab

open access: yesJPGN Reports, EarlyView.
Abstract Primary eosinophilic gastrointestinal disorders beyond the esophagus (EGIDs) are rare, predominantly Th2‐mediated inflammatory conditions, affecting various segments of the gastrointestinal tract. We report the case of a 12‐year‐old boy with recurrent abdominal pain, peripheral eosinophilia, and progressive gastritis, duodenitis, and enteritis
Almudena Sánchez‐Ramírez   +6 more
wiley   +1 more source

Peripheral blood cytokine levels in paediatric‐onset inflammatory bowel disease: A systematic review and meta‐analysis

open access: yesJPGN Reports, EarlyView.
Abstract Objectives We aimed to summarise findings on blood cytokine levels in patients with paediatric‐onset inflammatory bowel disease (PIBD) compared to healthy controls. Methods This systematic review followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta‐Analyses) guidelines and was registered at Prospero (CRD42024579684 ...
Sabine Jansson   +7 more
wiley   +1 more source

Assessing attitudes, access, barriers, and facilitators to multidisciplinary care in pediatric inflammatory bowel disease

open access: yesJPGN Reports, EarlyView.
Abstract Objective Multidisciplinary care is recommended for pediatric inflammatory bowel disease (IBD). This study aims to describe provider attitudes, barriers, and facilitators regarding multidisciplinary care in pediatric IBD, and explore associations between multidisciplinary care access and center‐level factors.
Nicole Davidson   +6 more
wiley   +1 more source

Treatment and Outcomes for Patients With Inadequate Lymphadenectomy After Resection of Stage II Small Bowel Adenocarcinoma

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Adjuvant chemotherapy (AC) is considered for patients with stage II small bowel adenocarcinoma (SBA) with an inadequate lymphadenectomy; however, the prognostic role of additional high‐risk features (T4 primary, positive resection margin, poorly differentiated tumor, or lymphovascular invasion) is unknown.
Jackson A. Baril   +8 more
wiley   +1 more source

Placebo rates in randomized clinical trials of ulcerative colitis: an individual patient data meta-analysis [PDF]

open access: hybrid
Virginia Solitano   +17 more
openalex   +1 more source

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