Results 31 to 40 of about 126,687 (241)
Calorimeter for Real-Time Dosimetry of Pulsed Ultra-High Dose Rate Electron Beams
Frontiers in Physics, 2020 An aluminum calorimeter was investigated as a possible real-time dosimeter for electron beams with an ultra-high dose per pulse (DPP), as used in FLASH radiation therapy (a few Gy/pulse). Ionization chambers, the most widely used active dosimeter type in
Alexandra Bourgouin +9 more
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In situ correction of recombination effects in ultra-high dose rate irradiations with protons
Physics in Medicine & Biology, 2023 Abstract Background. At the Center for Proton Therapy at the Paul Scherrer Institute (PSI) the delivery of proton radiation is controlled via gas-based ionization chambers: the beam is turned off when a certain amount of preset charge has been collected.
Schaefer, R., Psoroulas, S., Weber, D.C.
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Radiation Oncology, 2022 Background There is currently significant interest in assessing the role of oxygen in the radiobiological effects at ultra-high dose rates. Oxygen modulation is postulated to play a role in the enhanced sparing effect observed in FLASH radiotherapy ...
Pankaj Chaudhary +22 more
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Flash Radiotherapy: Innovative Cancer Treatment
Encyclopedia, 2023 Flash radiotherapy (Flash-RT) is an innovative technique used in radiotherapy for cancer treatment because it delivers an extremely high dose of radiation (>40 Gy/s) to the tumour in a very short period of time, typically within a fraction of a second ...
James C. L. Chow, Harry E. Ruda
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Frontiers in PhysicsVery High-Energy Electrons (VHEE) present a promising innovation in radiation therapy (RT), particularly for the treatment of deep-seated tumors using Ultra High Dose Rate (UHDR) within the framework of FLASH-RT.
J. H. Pensavalle +34 more
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Hydrated electron yield dependence on instantaneous dose rates with electron ultra-high dose rate (UHDR) irradiation. [PDF]
Phys Med BiolAbstract Objective. The aim of this study was to quantify the characteristic transient production yield of hydrated electrons (G-value) in water under ultra-high dose rates (UHDR) with electron irradiation. Changes in this yield with UHDR irradiation may provide insights into the radiation chemistry origins of the ...
Cao X +5 more
europepmc +3 more sources
The influence of beam parameters on FLASH effect
Frontiers in OncologyUltra-high dose rate radiotherapy (FLASH-RT) is typically defined as an external beam radiotherapy that utilizes a dose rate of 40 Gy/s or higher, compared with conventional dose rate radiotherapy (≤0.1 Gy/s).
Binwei Lin +15 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Cellular irradiations with laser-driven carbon ions at ultra-high dose rates
Physics in Medicine & Biology, 2023 Abstract Objective. Carbon is an ion species of significant radiobiological interest, particularly in view of its use in cancer radiotherapy, where its large Relative Biological Efficiency is often exploited to overcome radio resistance.
Chaudhary, Pankaj +13 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source