Results 111 to 120 of about 12,390 (209)

Clinical Outcomes of Gemcitabine Plus Nab‐Paclitaxel‐Based Chemoradiotherapy in a Multidisciplinary Treatment Strategy for Locally Advanced Pancreatic Cancer (NUPAT‐05): A Prospective, Single‐Arm, Phase II Study

International Journal of Cancer, EarlyView.
ABSTRACT Although chemoradiotherapy (CRT) has exhibited activity against locally advanced pancreatic cancer (LAPC), no standard regimen has been established. We previously completed a Phase I trial of CRT with gemcitabine plus nab‐paclitaxel (GnP) and established the recommended dose.
Hironori Yamada, Haruyoshi Tanaka, Suguru Yamada, Hideki Takami, Masamichi Hayashi, Nobuhiko Nakagawa, Keisuke Kurimoto, Yoshikuni Inokawa, Nobuyuki Watanabe, Takuya Ishikawa, Masayuki Okumura, Hiroshi Ogawa, Masahiko Ando, Osamu Maeda, Junpei Yamaguchi, Shinji Naganawa, Hiroki Kawashima, Tsutomu Fujii, Yukihiro Yokoyama, Tomoki Ebata, Mitsuro Kanda   +20 more
wiley   +1 more source

A prototype scintillator real-time beam monitor for ultra-high dose rate radiotherapy. [PDF]

Med Phys
Levin DS, Friedman PS, Ferretti C, Ristow N, Tecchio M, Litzenberg DW, Bashkirov V, Schulte R.   +7 more
europepmc   +1 more source

The Use of Combination Palliative Radiotherapy and Single‐Agent Immunotherapy for the Management of Head and Neck Squamous Cell Carcinoma (HNSCC) in the United Kingdom (UK)

International Journal of Cancer, EarlyView.
ABSTRACT Clinical data on combined Immunotherapy (IO) and palliative radiotherapy (RT) in HNSCC is scarce. HNSCC Palliative RT differs from curative intent RT as it does not involve elective nodal irradiation; therefore, an immune response may be more likely.
Chris Hurt, Sarah Park, Jonathan Chambers, Caroline Brammer, Matthew Griffin, Vishnu Harilal, Ruth Stone, Puteri Abdul Haris, Rebecca Shakir, Louise Karsera, Will Ince, Femi Adeoye, Daljit Gahir, James Lester, Ehiosa Charles Okuofo, Saira Khalique, Mayumi Forster, Philippa Smith, Oliver Donnelly, Lyndon Ridges‐Jones, James Hesford, Naomi Cole   +21 more
wiley   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

The Effects of Angiotensin Receptor Neprilysin Inhibitor on Endoplasmic Reticulum Stress in Doxorubicin‐Mediated Cardiomyopathy‐Associated Heart Failure Model in Rats

Journal of Applied Toxicology, EarlyView.
ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan, Meryem İlkay Karagül, Hatice Oruç Demirbağ, Ebru Balli   +3 more
wiley   +1 more source

Novel Bragg peak FLASH radiotherapy: treatment of base-of-skull tumors within existing clinical guidelines. [PDF]

Front Oncol
Pennock M, Selvaraj B, Cheng C, Kyler A, Lin H, Hasan S, Chhabra A, Choi JI, Bakst R, Kabarriti R, Lee NY, Simone CB, Kang M.   +12 more
europepmc   +1 more source

Optimising hypoxia PET imaging and its applications in guiding targeted radiation therapy for non‐small cell lung cancer: a scoping review

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 106-118, March 2025.
This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley   +1 more source

Scintillating Micro-Probe Detectors for Conventional and FLASH Proton Dosimetry: Optical Transport and Geometry Modeling. [PDF]

Bioengineering (Basel)
Subedi SK, Debnath SBC.
europepmc   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Transoral Robotic Surgery in Head and Neck Oncology: A Scoping Review of Evidence, Technological Advancements, and Future Trajectories

Journal of Surgical Oncology, EarlyView.
ABSTRACT Robotic surgery has transformed head and neck cancer (HNC) treatment. This scoping review synthesizes evidence on transoral robotic surgery (TORS), focusing on applications, limitations, and future directions. Following PRISMA‐ScR guidelines, this review used the PCC framework (Population: HNC patients; Concept: technological advancements ...
Anna Luíza Damaceno Araújo, Karthik N. Rao, Juan P. Rodrigo, Vincent Vander Poorten, Orlando Guntinas‐Lichius, Alfio Ferlito, Luiz Paulo Kowalski   +6 more
wiley   +1 more source