Results 131 to 140 of about 12,390 (209)

Editorial: Harnessing the potential of FLASH: questions we must address prior to effective clinical translation

Frontiers in Oncology
Per Rugaard Poulsen, Kevin M. Prise, Ranald I. MacKay   +2 more
doaj   +1 more source

The Choice Between Definitive Radiotherapy and Surgery for Cervical Cancer With Different Histology in Current Clinical Practice

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT For cervical cancer, the choice between definitive radiotherapy (RT) and surgery has long been a topic of debate. Clinical factors, including histology and tumor burden, have been examined in prior studies. Given recent advances in RT and the incorporation of concurrent chemotherapy, our study seeks to assess the optimal treatment modality for
Yu‐Lun Wu, Chen‐Wei Ho, Wen‐Shiung Liou, Chun‐Hao Yin, Jin‐Shuen Chen, Yao‐Shen Chen, Yu‐Wei Lin, Ju‐Chun Chien   +7 more
wiley   +1 more source

Harnessing the sparing effect of FLASH-RT: From phenomenon observation, radiophysical determinants to molecular mechanisms and synergistic strategies. [PDF]

Mater Today Bio
Dou Z, Lei H, Yang J, Li M, Wang S, Bao X, Ma L, Li J, Yin Y, Dai T.   +9 more
europepmc   +1 more source

Cochlear Implants for Radiation‐Induced Hearing Loss in Nasopharyngeal Cancer: A Systematic Review

The Laryngoscope, EarlyView.
ABSTRACT Objectives To evaluate the safety and efficacy of cochlear implantation for auditory rehabilitation in patients with nasopharyngeal carcinoma (NPC) after radiation. Data Sources CINAHL, Cochrane Library, PubMed, and Scopus were searched from inception through February 2026.
Kaitlyn A. Roberts, Lauren E. Williamson, Shaun A. Nguyen, Lucas C. Licaj, Sami I. Nassar, Jacqueline P. Nguyen, Jason G. Newman, Ted A. Meyer   +7 more
wiley   +1 more source

MR-Guided Adaptive Radiotherapy in Lung Cancer: Current Landscape and Future Directions. [PDF]

Cancers (Basel)
Ocanto A, Teja M, Gonsalves D, Vásquez W, Navarro-Domenech I, Moreno-Jimenez M, Guardia G, Urias D, Crespo S, Temes M, Hernández N, Senan S, Moghanaki D, Morera R, Azinovic I, Luna J, Couñago F.   +16 more
europepmc   +1 more source

Hypoxia‐Induced ADAM23 Drives Neuron–Tumor Crosstalk and Therapeutic Resistance in Hepatocellular Carcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT Hypoxia and nutrient deprivation are fundamental drivers of tumor aggressiveness and therapeutic resistance in hepatocellular carcinoma (HCC). While the involvement of neural components in the tumor microenvironment (TME) is increasingly recognized, the molecular transducers linking metabolic stress to neuron–tumor crosstalk remain elusive ...
Taehyun Park, Soeun Kim, Hyunjung Cho, Johyeon Nam, Dayoung Choi, Misu Lee   +5 more
wiley   +1 more source

The Tumor-Bed Boost Irradiation in Early-Stage Breast Cancer 30 Years After the Landmark Trials: What Is New? [PDF]

J Pers Med
Benevento I, Solazzo A, Tortoreto F, Boboc GI, Floreno B, Rago L, D'Andrea B, Montagna A, Bianculli A, Piscitelli A, Sanna F, Campoccia S, Ciabattoni A, Lazzari G.   +13 more
europepmc   +1 more source

Integration of scRNA‐Seq and scATAC‐Seq Revealed the Role of lncRNA RP11‐661C8.2 by Promoting EMT in Clear Cell Renal Cell Carcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT Long noncoding RNAs (lncRNAs) play an important role in tumor progression. However, most of the previously discovered lncRNAs that promote or inhibit tumor progression were derived from bulk RNA‐seq results. Data from single‐cell RNA sequencing (scRNA‐seq) and single‐cell assay for transposase‐accessible chromatin using sequencing (scATAC‐seq)
Jizhen Cen, Xuefang Liang, Zheng Wen, Shengzhu Huang, Jiaping Li, Haibiao Yan, Kaiqiang Tang, Guifen Zhou, Ning Liang, Qi Zheng, Cheng Su, Zengnan Mo, Zhenyuan Yu   +12 more
wiley   +1 more source

The value of breast brachytherapy boost in the current era: a narrative literature review from the GEC-ESTRO breast cancer working group. [PDF]

Clin Transl Radiat Oncol
Montesinos IM, Konat-Bąska K, Guinot JL, Polgar C, Strnad V, Hannoun-Levi JM, Gutierrez C, GEC-ESTRO Breast Cancer Working Group.   +7 more
europepmc   +1 more source

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

Medicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo, Kaeun Chae, Jueun Lee, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source