Results 151 to 160 of about 12,390 (209)

COX5A promotes cell progression and cisplatin‐resistance by alleviating mitochondrial dysfunction in head and neck squamous cell carcinoma

Precision Medical Sciences, EarlyView.
COX5A promotes cell progression and cisplatin‐resistance and alleviates mitochondrial dysfunction. ISG15 shows a reversing role with COX5A. Targeting the COX5A‐mediated mitochondrial metabolic pathway may offer a novel therapeutic approach to enhance cisplatin sensitivity in HNSCC.
Nannan Guo, Zhangyu Yao, Bo Gui, Qingya Sun, Yihan Tang, Tingting Hu, Yanbin Zhao, Fangzhou Liu   +7 more
wiley   +1 more source

Experimental validation of time-driven proton PBS FLASH delivery on a clinical proton therapy system. [PDF]

Phys Imaging Radiat Oncol
Krzempek D, Gajewski J, Jabłoński H, Spaleniak A, Komenda W, Guguła K, Kamiński M, Hankiewicz M, Pasiecznik T, Suder K, Malinowski L, Nowak T, Mojżeszek N, Bałamut M, Rogalski P, Kopeć R, Rydygier M.   +16 more
europepmc   +1 more source

Precision medicine in cancer: A comprehensive review of advanced cancer diagnosis technologies and personalized treatment strategies

Precision Medical Sciences, EarlyView.
The translational pipeline of precision medicine in clinical oncology. Schematic overview of the individualized cancer care workflow. (1) Input: Patient samples undergo multi‐omic profiling via NGS, single‐cell diagnostics, spatial maps, and epigenetic sequencing.
Asif Jan, Bushra Waheed, Rani Akbar, Daniel Dubwa   +3 more
wiley   +1 more source

Towards FLASH Radiotherapy in Lung Cancer: A Review on Preclinical Evidence and Technical Feasibility. [PDF]

Cancers (Basel)
Visser SN, Habraken SJM, Puspitasari-Kokko A, Zur Horst AH, Rasch CRN, van Doorn-Wink KCJ.   +5 more
europepmc   +1 more source

177Lu‐labeled amidoxime‐functionalized biodegradable microspheres for transarterial radioembolization of hepatocellular carcinoma

Precision Radiation Oncology, EarlyView.
Scheme 1. Schematic illustration of the synthesis and therapeutic evaluation of PLA‐g‐PAO microspheres (PLA‐g‐PAO‐Ms). Monodisperse PLA microspheres (PLA‐Ms) were initially fabricated via microfluidic technology. Surface grafting of acrylonitrile monomers was subsequently achieved through radiation‐induced graft polymerization, followed by ...
Xingliang Liu, Gang Wang, Zhenwen Zhao, Haoyu Wang, Hongyu Chen, Xiao Xu, Jingdong Li, Hongjuan Ma   +7 more
wiley   +1 more source

FocaSaBra: a prospective phase II study on focal salvage brachytherapy for prostate cancer recurrence after radiotherapy - trial design. [PDF]

Rep Pract Oncol Radiother
Burchardt WM, Kluska A, Chicheł A, Zwierzchowski G, Burchardt E, Bielęda G, Chyrek AJ.   +6 more
europepmc   +1 more source

An evaluation of radiotherapy and response in the management of perivascular epithelioid cell tumors. [PDF]

Br J Radiol
Krcek R, Nesterova K, Santiago AT, Aubrey R, Michael MJ, Roohani S, Peretz H, Gupta A, Chung P.   +8 more
europepmc   +1 more source

The efficacy of concurrent chemoradiotherapy with or without nimotuzumab in high‐risk patients with locally advanced head and neck squamous cell carcinoma post‐surgery: A real‐world study

Precision Radiation Oncology, EarlyView.
Figure 1 Patient selection flowchart. CCRT, concurrent chemoradiotherapy; NCCRT, nimotuzumab and concurrent chemoradiotherapy. Abstract Purpose Patients with locally advanced head and neck squamous cell carcinoma (LA‐HNSCC) harboring high‐risk pathological features after radical surgery face high recurrence rates.
Yuejia Zhou, Linting Zhang, Wenjuan Lai, Jingyun Tan, Jing Gao, Yajie Liu, Shubin Wang, Feng Peng, Gangling Tong   +8 more
wiley   +1 more source

Feasibility of Urethra‐Sparing Ultra‐Hypofractionated Three‐Dose‐Level Radiotherapy for Prostate Cancer with a Dominant Intraprostatic Lesion Abutting the High‐Dose Avoidance Zone

Precision Radiation Oncology, EarlyView.
Ultra‐hypofractionated three‐dose‐level radiotherapy allows safe dose escalation to dominant intraprostatic lesions near the urethra while maintaining full coverage of pelvis and prostate and respecting urethral and organ‐at‐risk constraints. Abstract This planning study evaluated ultra‐hypofractionated three‐dose‐level radiotherapy for prostate cancer
Annalisa Muscato, Denis La Fauci, Anna Viola, Valentina Zagardo, Gianluca Ferini   +4 more
wiley   +1 more source

Abscopal responses following stereotactic ablative radiotherapy during immune checkpoint inhibitor therapy in metastatic renal cell carcinoma: protocol for the prospective multicentre observational AURICRE study in Japan. [PDF]

BMJ Open
Chen Z, Onishi H, Mitsui T, Nakao A, Yokomichi H, Tsukahara M, Mochizuki S, Marino K, Komiyama T.   +8 more
europepmc   +1 more source