Results 21 to 30 of about 104,266 (277)

Error-Related Brain Activity in Patients With Obsessive-Compulsive Disorder and Unaffected First-Degree Relatives: Evidence for Protective Patterns

Biological Psychiatry Global Open Science, 2022
Background: Indicators of increased error monitoring are associated with obsessive-compulsive disorder (OCD), as shown in electroencephalography and functional magnetic resonance imaging studies.
Rosa Grützmann, Christian Kaufmann, Olga A. Wudarczyk, Luisa Balzus, Julia Klawohn, Anja Riesel, Katharina Bey, Michael Wagner, Stephan Heinzel, Norbert Kathmann   +9 more
doaj   +1 more source

Familial hypertrophic cardiomyopathy: vectorcardiographic findings in echocardiographically unaffected relative. [PDF]

Heart, 1982
The electrocardiographic and vectorcardiographic (Frank system) features of the first degree relatives of subjects with documented familial hypertrophic cardiomyopathy were analysed. A total of nine affected members and 29 relatives were examined in four families.
F, Loperfido, R, Fiorilli, A, Digaetano, M, Di Gennaro, P, Santarelli, F, Bellocci, E, Coppola, P, Zecchi   +7 more
openaire   +2 more sources

High-sensitive C-reactive protein and homocysteine levels in patients with newly diagnosed bipolar disorder, their first-degree relatives, and healthy control persons—Results from a clinical study

European Psychiatry, 2020
BackgroundChanges in inflammatory and metabolic markers are implicated in the pathogenesis in both the development and progression of bipolar disorder (BD).
Marc Østergaard Nielsen, Nanna Aagaard Petersen, Klara Coello, Sharleny Stanislaus, Sigurd A. Melbye, Hanne Lie Kjærstad, Kimie Stefanie Ormstrup Sletved, Ruth Frikke-Schmidt, Roger S. McIntyre, Maj Vinberg, Lars Vedel Kessing   +10 more
doaj   +1 more source

An ex vivo test to investigate genetic factors conferring susceptibility to atypical haemolytic uremic syndrome

Frontiers in Immunology, 2023
IntroductionComprehensive genetic analysis is essential to clinical care of patients with atypical haemolytic uremic syndrome (aHUS) to reinforce diagnosis, and to guide treatment.
Sara Gastoldi, Sistiana Aiello, Miriam Galbusera, Matteo Breno, Marta Alberti, Elena Bresin, Caterina Mele, Rossella Piras, Lucia Liguori, Donata Santarsiero, Ariela Benigni, Giuseppe Remuzzi, Marina Noris   +12 more
doaj   +1 more source

Neural endophenotypes and predictors of laryngeal dystonia penetrance and manifestation

Neurobiology of Disease, 2021
Focal dystonias are the most common forms of isolated dystonia; however, the etiopathophysiological signatures of disorder penetrance and clinical manifestation remain unclear. Using an imaging genetics approach, we investigated functional and structural
Sanaz Khosravani, Gang Chen, Laurie J. Ozelius, Kristina Simonyan   +3 more
doaj   +1 more source

Verbal learning in schizophrenia in remission, first-degree relatives, and correlation to symptoms

Open Journal of Psychiatry and Allied Sciences, 2022
Background: Cognitive impairments are fundamental in schizophrenia with verbal memory impairments commonly occurring not only in patients but also in unaffected genetically susceptible individuals.
Sunny Chattopadhyay, Om Prakash Singh, Sayanti Ghosh   +2 more
doaj   +1 more source

Pro-inflammatory cytokine alterations in unaffected first-degree relatives of schizophrenia patients

European Psychiatry, 2021
Introduction A growing body of evidence in both chronic and first-episode schizophrenia report increased expression of pro-inflammatory substances in the blood and cerebrospinal fluid of patients.
A. Kurtulmus
doaj   +1 more source

Error-related brain activity as a transdiagnostic endophenotype for obsessive-compulsive disorder, anxiety and substance use disorder [PDF]

, 2019
Background Increased neural error-signals have been observed in obsessive-compulsive disorder (OCD), anxiety disorders, and inconsistently in depression. Reduced neural error-signals have been observed in substance use disorders (SUD). Thus, alterations
Bey, Katharina, Grützmann, Rosa, Heinzel, Stephan, Kathmann, Norbert, Kaufmann, Christian, Klawohn, Julia, Lennertz, Leonhard, Riesel, Anja Riesel, Wagner, Michael   +8 more
core   +1 more source

Autoimmunity to tropomyosin isoforms in ulcerative colitis (UC) patients and unaffected relatives [PDF]

Clinical and Experimental Immunology, 1998
SUMMARYAutoimmunity to cytoskeletal protein tropomyosin (TM) has been demonstrated in UC. However, the TM isoforms involved in this IgG-mediated autoimmune response in UC and the possible presence of serum IgG antibodies against TM (hTMs IgG) in unaffected UC relatives are unknown.
L, Biancone, G, Monteleone, R, Marasco, F, Pallone   +3 more
openaire   +2 more sources

Similar and different grey matter deficits in schizophrenia patients and their unaffected biological relatives

Frontiers in Psychiatry, 2013
Neuroimaging studies have revealed significant reductions in the grey matter of several brain regions in patients with schizophrenia, a neuropsychiatric disorder with high hereditability.
Yuan eXiao, Su eLui, Wenjing eZhang, Li eYao, Qiyong eGong   +4 more
doaj   +1 more source