Visual attention in autism families: ‘unaffected’ sibs share atypical frontal activation [PDF]
Background: In addition to their more clinically evident abnormalities of social cognition, people with autism spectrum conditions (ASC) manifest perturbations of attention and sensory perception which may offer insights into the underlying neural ...
Baron-Cohen, S, Belmonte, MK, Gomot, M
core +1 more source
Few studies have explored the differences in clinical psychopathology between youth at high risk for psychosis and those at familial high risk for psychosis.
Lourdes Nieto +5 more
doaj +1 more source
The distinct features of microbial 'dysbiosis' of Crohn's disease do not occur to the same extent in their unaffected, genetically linked kindred [PDF]
Background/Aims: Studying the gut microbiota in unaffected relatives of people with Crohn’s disease (CD) may advance our understanding of the role of bacteria in disease aetiology. Methods: Faecal microbiota composition (16S rRNA gene sequencing),
Bertz, Martin +11 more
core +4 more sources
Autonomic Dysfunction in Unaffected First-Degree Relatives of Patients Suffering From Schizophrenia [PDF]
Recent studies revealed cardiac autonomic dysfunction in patients with acute schizophrenia, which appears to be mainly related to reduced vagal and increased sympathetic modulation. To understand the significance of cardiac autonomic function in patients with schizophrenia, we extended these studies to relatives of patients.
Karl-Jürgen, Bär +9 more
openaire +2 more sources
Temporal reproduction and its neuroanatomical correlates in adults with attention deficit hyperactivity disorder and their unaffected first-degree relatives [PDF]
Background: Little is known about time perception, its putative role as cognitive endophenotype, and its neuroanatomical underpinnings in adults with attention deficit hyperactivity disorder (ADHD). Method: Twenty adults with ADHD, 20 unaffected
B. J. Sahakian +9 more
core +1 more source
Olfactory function in patients with nonsyndromic orofacial clefts and their unaffected relatives [PDF]
Nonsyndromic orofacial clefting is one of the most frequently occurring congenital conditions. The aim of the study was to investigate the prevalence and nature of reduced olfactory function in patients with nonsyndromic cleft lip and/or cleft palate (NSCL/P) and their unaffected first‐degree relatives.
Roosenboom, Jasmien +10 more
openaire +3 more sources
ObjectiveTo study the prospective memory deficits of obsessive-compulsive disorder patients and unaffected first-degree relatives of patients, so as to validate the possibility of prospective memory as an endophenotype of obsessive-compulsive disorder ...
Wei Zhen +3 more
doaj +1 more source
Reduced face identity aftereffects in relatives of children with autism. [PDF]
Autism is a pervasive developmental condition with complex aetiology. To aid the discovery of genetic mechanisms, researchers have turned towards identifying potential endophenotypes - subtle neurobiological or neurocognitive traits present in ...
Fiorentini, Chiara +4 more
core +2 more sources
Clustering of Schizotypal Features in Unaffected First-Degree Relatives of Schizophrenia Patients [PDF]
Meehl conceptualized schizotypy as the phenotypic manifestations of a neural integrative defect resulting from a schizophrenia diathesis. The majority of schizotypy studies recruited subjects from the general population and revealed a multidimensional construct.
Lui, Simon S. Y. +9 more
openaire +3 more sources
Impaired response inhibition and excess cortical thickness as candidate endophenotypes for trichotillomania. [PDF]
Trichotillomania is characterized by repetitive pulling out of one's own hair. Impaired response inhibition has been identified in patients with trichotillomania, along with gray matter density changes in distributed neural regions including frontal ...
Chamberlain, Samuel R. +4 more
core +3 more sources

