TfR1 facilitates influenza virus endocytosis and uncoating by interacting with NA and M1 via extracellular and intracellular domains. [PDF]
PLoS PathogWang X +19 more
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Enhancement of surface tribology, mechanical, and electrical properties of UHMWPE <i>via</i> graphene nanoplatelets coating and electron beam irradiation. [PDF]
RSC AdvAnekratmontre T +3 more
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Principles of polyoma- and papillomavirus uncoating
Medical Microbiology and Immunology, 2012Virus particles are vehicles for transmission of the viral genetic information between infected and uninfected cells and organisms. They have evolved to self-assemble, to serve as a protective shell for the viral genome during transfer, and to disassemble when entering a target cell.
Mario Schelhaas
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Uncoating of HIV-1 requires cellular activation
Virology, 2005 Uncoating is an essential step in viral replication cycle. Little is known about the mechanism and requirement of HIV uncoating. Using an in vitro uncoating model, we demonstrate here that the uncoating of HIV-1 was efficiently induced by lysate from ...
Prasert Auewarakul +2 more
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The effect of capsid mutations on HIV-1 uncoating
Virology, 2007 Efficient uncoating requires not only an optimal cellular environment, but also some intrinsic properties of the viral capsid protein itself. Using an in vitro uncoating model, we demonstrated that substitution of each serine residue with alanine at the ...
Prasert Auewarakul
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Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating [PDF]
Cell Host and Microbe, 2021 Enterovirus uncoating receptors bind at the surface depression ("canyon") that encircles each capsid vertex causing the release of a host-derived lipid called "pocket factor" that is buried in a hydrophobic pocket formed by the major viral capsid protein,
Longfa Xu, Qingbing Zheng, Rui Zhu
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Early cytoplasmic uncoating is associated with infectivity of HIV-1
Proceedings of the National Academy of Sciences of the United States of America, 2017 Significance After fusion, HIV delivers its capsid formed of CA proteins into the cytoplasm. The regulated disassembly of the capsid (uncoating) is critical to the timely exposure of the viral genome and infection. The timing of this process is
João I Mamede +2 more
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How Influenza Virus Uses Host Cell Pathways during Uncoating
Cells, 2021 Influenza is a zoonotic respiratory disease of major public health interest due to its pandemic potential, and a threat to animals and the human population.
Étori Aguiar Moreira +2 more
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Uncoating of human rhinoviruses
Reviews in Medical Virology, 2010AbstractHuman rhinoviruses (HRVs) are a major cause of the common cold. The more than one hundred serotypes, divided into species HRV‐A and HRV‐B, either bind intercellular adhesion molecule 1 (major group viruses) or members of the low‐density lipoprotein receptor (minor group viruses) for cell entry.
Renate, Fuchs, Dieter, Blaas
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HIV-1 uncoating: connection to nuclear entry and regulation by host proteins
Virology, 2014 The RNA genome of human immunodeficiency virus type 1 (HIV-1) is enclosed by a capsid shell that dissociates within the cell in a multistep process known as uncoating, which influences completion of reverse transcription of the viral genome.
Zandrea Ambrose, Christopher Aiken
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