The Effects of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) on Brown Adipogenesis in Stem Cell Culture [PDF]
Polyunsaturated fatty acids (PUFAs), especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are major maternal dietary supplements due to their positive benefits on neurological tissue growth during the first 12 weeks of gestation ...
Dahlem, Darynne
core +2 more sources
Unjamming Transition as a Paradigm for Biomechanical Control of Cancer Metastasis
ABSTRACT Tumor metastasis is a complex phenomenon that poses significant challenges to current cancer therapeutics. While the biochemical signaling involved in promoting motile phenotypes is well understood, the role of biomechanical interactions has recently begun to be incorporated into models of tumor cell migration.
Grace Cai+2 more
wiley +1 more source
Background and Objective: The synthesis of uncoupling protein 1 (UCP1) in adipose tissue plays an important role in providing resistance and prevention of fat accumulation, weight gain and obesity.
Keyvan Hejazi+4 more
doaj
CTRP9 Promotes Brown Adipose Tissue Lipolysis in Mice Fed a High-Fat Diet
Background: This study aimed to elucidate the molecular mechanism through which C1q/tumor necrosis factor (TNF)-related protein 9 (CTRP9) acts in the formation and differentiation of brown adipose tissue (BAT).
Hua Guan+8 more
doaj +1 more source
PEK14: A Kinesin‐4 Necessary for Male‐Derived Fertility in Arabidopsis thaliana
ABSTRACT Of the 61 kinesins annotated in Arabidopsis thaliana, many are still without assigned function. Here, we have screened an insertional mutant library of Arabidopsis pollen‐expressed kinesins for fertility defects. Insertional mutants for three kinesins showed a significant reduction in seed set.
Isabella N. Mendes+6 more
wiley +1 more source
Fighting obesity by targeting factors regulating beige adipocytes. [PDF]
Purpose of reviewThe current review provides an update on secreted factors and mechanisms that promote a thermogenic program in beige adipocytes, and their potential roles as therapeutic targets to fight obesity.Recent findingsWe outline recent studies ...
Koliwad, Suneil K+2 more
core +1 more source
Identification and postnatal developmental characteristics of brown adipose tissue in yak calves
Background Brown adipose tissue (BAT) provides newborn mammals with a critical capacity for non‐shivering thermogenesis and enables their adaptation to the cold of the extrauterine environment.
Chen Fuju, Zhao Yutian, Ling Xiaodong
doaj +1 more source
High Level of Uncoupling Protein 1 Expression in Muscle of Transgenic Mice Selectively Affects Muscles at Rest and Decreases Their IIb Fiber Content [PDF]
Elodie Couplan+18 more
openalex +1 more source
Uncoupling Protein-1 Modulates Anxiety-Like Behavior in a Temperature-Dependent Manner. [PDF]
Sideromenos S+7 more
europepmc +1 more source
Hydroxylated derivatives of arachidonic acid play crucial roles in physiology and inflammation response, with distinct biological effects for (R)‐ and (S)‐enantiomers, highlighting their pharmaceutical relevance. Here, we harness recombinant unspecific peroxygenases (UPOs)—from the fungi Coprinopsis cinerea (rCciUPO) and Agrocybe aegerita (rAaeUPO ...
Alejandro González-Benjumea+7 more
wiley +1 more source