Results 171 to 180 of about 69,972 (249)

Radish Seed Exerts Anti-Diabetic and Obesity-Reducing Effects in Mice by Promoting the Activation of Uncoupling Protein 1 and Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-α. [PDF]

J Evid Based Integr Med
Wang YC, Hsu YA, Lin SC, Chien LS, Chen JJY, Wu MY, Lin HJ, Chen CS, Huang YQ, Tsai YC, Wan L.   +10 more
europepmc   +1 more source

Brown adipose tissue lipoprotein and glucose disposal is not determined by thermogenesis in uncoupling protein 1-deficient mice. [PDF]

J Lipid Res, 2020
Fischer AW, Behrens J, Sass F, Schlein C, Heine M, Pertzborn P, Scheja L, Heeren J.   +7 more
europepmc   +1 more source

Environmental chemicals and the tumor immune microenvironment

iMeta, EarlyView.
Impact of representative environmental chemicals on tumor immune microenvironment (TIME). Representative environmental chemicals are ubiquitously distributed across air, soil, aquatic systems, and biota. These toxicants enter the human body via multiple exposure routes, including inhalation, dietary intake, and dermal absorption, subsequently ...
Tongtong Zhang, Yanxia Hu, Weiran Zhang, Yang Jin, Chaoyang Sun, Afshin Samali, Shunqing Xu, Xia Sheng   +7 more
wiley   +1 more source

Glycerol kinase stimulates uncoupling protein 1 expression by regulating fatty acid metabolism in beige adipocytes. [PDF]

J Biol Chem, 2020
Iwase M, Tokiwa S, Seno S, Mukai T, Yeh YS, Takahashi H, Nomura W, Jheng HF, Matsumura S, Kusudo T, Osato N, Osato N, Matsuda H, Inoue K, Kawada T, Goto T.   +15 more
europepmc   +1 more source

Spatial multi‐omics unveils sphingolipid metabolic reprogramming within the retinal pathological niche

iMeta, EarlyView.
Spatial multi‐omics of the mouse ocular globe after retinal ischemia‐reperfusion (RIR) injury identifies the ganglion cell layer (GCL) as an immunometabolic niche where Trem2+ microglia closely associate with stressed retinal ganglion cells (RGCs) through Trem2‐Apoe signaling.
Yunhong Shi, Jinpei Lin, Yi Wu, Shengsong Xu, Naiyuan Zhang, Yiji Pan, Anli Ren, Ying Fang, Yu Huang, Xiayin Zhang, Zhuoting Zhu, Yehong Zhuo, Honghua Yu   +12 more
wiley   +1 more source

Uncoupling protein-1 expression does not protect mice from diet-induced obesity.

Am J Physiol Endocrinol Metab, 2021
Wang H, Willershäuser M, Li Y, Fromme T, Schnabl K, Bast-Habersbrunner A, Ramisch S, Mocek S, Klingenspor M.   +8 more
europepmc   +1 more source

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source

Genetic Biomarkers in the Risk Assessment of Sudden Cardiac Events: A Personalized Approach

iNew Medicine, EarlyView.
Genetic insights into the risk assessment of sudden cardiac events. ABSTRACT Sudden cardiac events are the leading cause of death worldwide. Conventional risk stratification methods, which largely depend on clinical history, imaging, and electrocardiography, are usually inadequate for identifying high‐risk individuals, especially those without visible ...
Shrikant Verma, Sushma Verma, Mohammad Abbas, Tabrez Faruqui, Bashir Ahmad Mir, Farzana Mahdi   +5 more
wiley   +1 more source

Uncoupling protein 1-driven Cre (Ucp1-Cre) is expressed in the epithelial cells of mammary glands and various non-adipose tissues. [PDF]

Mol Metab
Kim K, Wann J, Kim HG, So J, Rosen ED, Roh HC.   +5 more
europepmc   +1 more source

Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells

Interdisciplinary Medicine, EarlyView.
Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen, Jiayi Wang, Jimin Yu, Yiran Zhou, Lihai Liu, Jing Liu, Liang Wang   +6 more
wiley   +1 more source