Results 191 to 200 of about 73,799 (284)

Effects of the Uncoupling Protein 1 (UCP1) A-3826G Polymorphism on Taste Preferences in Healthy Young Japanese Adults. [PDF]

Life (Basel)
Kokubun T, Kudo TA, Tominami K, Ishigaki H, Matsushita A, Izumi S, Tanaka T, Kawaguchi K, Hayashi Y, Sato H, Shoji N, Gengyo-Ando K, Adachi K, Nakai J, Hong G.   +14 more
europepmc   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Downregulation of uncoupling protein 1 by hypermethylation in gastric cancer activates <i>Rap1</i> signaling. [PDF]

World J Gastrointest Oncol
Chen YJ, Peng C, Wang LW, Chai JX, Wang JD, He QB.   +5 more
europepmc   +1 more source

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

Food Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima, István Dalmadi, Anna Jánosi, Krisztina Takács, Eszter Halmy   +4 more
wiley   +1 more source

An investigation into the role and regulation of uncoupling protein 1 (UCP 1)

, 2019
The use of the uncoupling protein inhibitor GDP was used to investigate UCP 1 dependent ROS production in BAT and thymus mitochondria. The effect of UCP 1 inhibition by GDP was then corroborated using UCP 1 ablated mice and their wild-type controls. It was shown that UCP 1 was capable of attenuating ROS production in isolated BAT mitochondria.
openaire   +1 more source

Preadipocyte Uncoupling Protein 1 Expression Invoked by Fibroblast Growth Factors Imprints on Post-Differentiation White and Brown Adipocyte Phenotype. [PDF]

FASEB J
Kuellmer K, Mönch C, Roch W, Wurmser C, Petersen PSS, Hermannsdóttir H, Hasic M, Emanuelli B, Fromme T.   +8 more
europepmc   +1 more source

Addendum to: Anti-obesity Effects of Artemisia annua Extract in Zucker Fatty Rats and High-Fat Diet Sprague Dawley Rats through Upregulation of Uncoupling Protein 1 (J Obes Metab Syndr 2021;30:32-43). [PDF]

J Obes Metab Syndr, 2022
Choi EY, Park CY, Ho SH, Park SJ, Kim D, Han B, Kim SH.   +6 more
europepmc   +1 more source

Establishment of THP-1 Monocytes with Compromised Mitochondrial Functions

, 2009
The process of inflammation is important for both normal health and in a number of diseases, such as metabolic disorders, autoimmune diseases, and neurodegenerative diseases. Mitochondria are vital for the functioning of all cells. It had been implicated
Chou, Tzu-wen Joy
core  

Combination of Lenvatinib and Antibiotics: A Potential Approach to Enhance Sensitivity in Differentiated Thyroid Cancer

International Journal of Cancer, EarlyView.
Although lenvatinib is the current first‐line therapy for radioiodine‐refractory differentiated thyroid carcinoma, its use is limited by severe side effects and reduced sensitivity. Here, the authors assessed the potential of sensitizing differentiated thyroid carcinoma tumor cells with limited lenvatinib responsiveness through the administration of ...
Celina Ablinger, Petra Huber‐Cantonati, Daniela D. Weber, Sarah Pichler, Georg Schischkow, Marta Garcia‐Miralles, Christian Pirich, Gundula Rendl, Teresa Kiener, Thomas Felder, Martin Geroldinger, Robert Terkola, Barbara Kofler, Johanna Pachmayr   +13 more
wiley   +1 more source

Investigating mitochondrial uncoupling protein 1 and leptin in the interplay of metabolic adaptation and inflammatory response of dairy cows during the peripartum period. [PDF]

Front Vet Sci
Arfuso F, Arrigo F, Rizzo M, Sisia G, Fiore E, Giannetto C, Liotta L, Piccione G, Lopreiato V.   +8 more
europepmc   +1 more source