Classical gonadoblastoma: its relationship to the “dissecting” variant and undifferentiated gonadal tissue [PDF]
Classical gonadoblastoma occurs almost entirely in the dysgenetic gonads of an individual who has a disorder of sex development. Approximately 40% of such neoplasms are bilateral.
Cheng, Liang, Roth, Lawrence M.
core +2 more sources
Sox9 downregulation in non-obstructive azoospermia by UTF1 and mediator role of POU5F1
Background Spermatogenesis is the process of producing mature sperm from Spermatogonial stem cells (SSCs) and this process requires a complex cooperation of different types of somatic and germ cells.
Mehdi Mehdinezhad Roshan +3 more
doaj +1 more source
Sexual differentiation and gonad development in striped mullet (Mugil cephalus L.) from South Carolina estuaries* [PDF]
This study examined the sexual differentiation and reproductive dynamics of striped mullet (Mugil cephalus L.) in the estuaries of South Carolina.
McDonough, Christopher J. +2 more
core +1 more source
Cancer treatment in childhood and testicular function : the importance of the somatic environment [PDF]
Testicular function and future fertility may be affected by cancer treatment during childhood. Whilst survival of the germ (stem) cells is critical for ensuring the potential for fertility in these patients, the somatic cell populations also play a ...
Hutka, Marsida +3 more
core +4 more sources
Undifferentiated type A spermatogonia are the foundation of fish spermatogenesis. This cell population includes the spermatogonial stem cell population, which is able to either self-renew or differentiate into cells that will generate the male gamete - the spermatozoa. Spermatogonia stem cells are located in a specific region of the testes known as the
de Paiva Camargo, Marília +4 more
openaire +3 more sources
Isolation of Undifferentiated and Early Differentiating Type A Spermatogonia from Pou5f1-GFP Reporter Mice [PDF]
Limited understanding of the mechanisms underlying self-renewal and differentiation of spermatogonial stem cells hampers our ability to develop new therapeutic and contraceptive approaches. Mouse models of spermatogonial stem cell development are key to developing new insights into the biology of both the normal and diseased testis.
Thomas, Garcia, Marie-Claude, Hofmann
openaire +2 more sources
Microgravity promotes differentiation and meiotic entry of postnatal mouse male germ cells.
A critical step of spermatogenesis is the entry of mitotic spermatogonia into meiosis. Progresses on these topics are hampered by the lack of an in vitro culture system allowing mouse spermatogonia differentiation and entry into meiosis. Previous studies
Manuela Pellegrini +7 more
doaj +1 more source
Identification of side population cells in mouse primordial germ cells and prenatal testis [PDF]
In mammals, the stem cells of spermatogenesis are derived from an embryonic cell population called primordial germ cells (PGCs). Spermatogonial stem cells displaying the "side population" (SP) phenotype have been identified in the immature and adult ...
De Felici, Massimo +6 more
core +2 more sources
Background Spermatogenesis is a complex process involving the self-renewal and differentiation of spermatogonia into mature spermatids in the seminiferous tubules.
Yue Liu, Yanqin Hu, Li Wang, Chen Xu
doaj +1 more source
Analysis of the gene expression profile of mouse male meiotic germ cells [PDF]
Wide genome analysis of difference in gene expression between spermatogonial populations from 7-day-old mice and pachytene spermatocytes from 18-day-old mice was performed using Affymetrix gene chips representing approximately 12,500 mouse known genes or
Capolunghi, F +11 more
core +2 more sources

