Results 91 to 100 of about 4,581 (187)

The sensitivity to X rays of mouse spermatogonia that are committed to differentiate and of differentiating spermatogonia

, 1992
In the CBA mouse the radiosensitivity of the undifferentiated spermatogonia that are committed to differentiate was determined by counting their more developed descendants 10 days after graded doses of X rays.
Huiskamp, R., van der Tweel, I., de rooij, D. G., van der Meer, Y., Davids, J. A.   +4 more
core   +1 more source

Sox9 downregulation in non-obstructive azoospermia by UTF1 and mediator role of POU5F1

BMC Research Notes
Background Spermatogenesis is the process of producing mature sperm from Spermatogonial stem cells (SSCs) and this process requires a complex cooperation of different types of somatic and germ cells.
Mehdi Mehdinezhad Roshan, Hossein Azizi, Mohammadreza Ashtari Majelan, Amirreza Niazi Tabar   +3 more
doaj   +1 more source

Rbm46 expression is restricted to spermatogonia, spermatocytes, and early round spermatids in the adult testis.

, 2022
(A) Violin plots showing relative mRNA levels from single cell (sc)RNA-seq data from adult mouse testes [4]. Undiff = undifferentiated; diff = differentiating; spg = spermatogonia; lep/zyg = leptotene + zygotene; pach = pachytene; spc = spermatocyte; tid
Sungkyoung Lee (11286780), Huijuan Feng (5451185), Matthew J. Sears (13840426), Fang Yang (123514), Brian P. Hermann (13840429), Christopher B. Geyer (13840432), P. Jeremy Wang (10204629), Yocelyn Recinos (5628695), Natoya J. Peart (13840420), Russ P. Carstens (13840435), Yoseph Barash (48182), Taylor A. Johnson (13840423), Mathieu Quesnel-Vallières (6995189), Chaolin Zhang (28120)   +13 more
core   +1 more source

Microgravity promotes differentiation and meiotic entry of postnatal mouse male germ cells.

PLoS ONE, 2010
A critical step of spermatogenesis is the entry of mitotic spermatogonia into meiosis. Progresses on these topics are hampered by the lack of an in vitro culture system allowing mouse spermatogonia differentiation and entry into meiosis. Previous studies
Manuela Pellegrini, Sara Di Siena, Giuseppina Claps, Silvia Di Cesare, Susanna Dolci, Pellegrino Rossi, Raffaele Geremia, Paola Grimaldi   +7 more
doaj   +1 more source

Expression Profile of NOTCH3 in Mouse Spermatogonia

, 2017
Stable and sustainable spermatogenesis is supported by the strict regulation of self-renewal and differentiation of spermatogonial stem cells (SSC), which are a rare population of undifferentiated spermatogonia.
Megumi Fujimagari, Yoshikazu Hirose, Tomomi Sato, Ryu Okada, Eri Koya, Yukio Nishina   +5 more
core   +1 more source

Expression of the pluripotency marker UTF1 is restricted to a subpopulation of early A spermatogonia in rat testis [PDF]

, 2008
The population of early A spermatogonia includes stem cells that possess spermatogonial stem cell properties. Recent reports suggest that these cells have the ability to regain pluripotent properties.
Korver, Cindy M., de Rooij, Dirk G., B. J L Eggen, Bragt, Maaike P.A. van,, Eggen, Bart J. L., Roepers-Gajadien, Hermien L., J. Bogerd, Eggen, Bart J.L.,, Okuda, Akihiko,, A. Okuda, Korver, Cindy M.,, A. M M van Pelt, H. L Roepers-Gajadien, Eggen, Bart J. L.; id_orcid, van Bragt, Maaike P. A., van Pelt, Ans M. M., Rooij, Dirk G. de,, Okuda, Akihiko, Bogerd, Jan, Bogerd, Jan,, Roepers-Gajadien, Hermien L.,, C. M Korver, Pelt, Ans M.M. van,, M. P A van Bragt, D. G de Rooij   +24 more
core   +1 more source

Expression of transcriptional factor EB (TFEB) in differentiating spermatogonia potentially promotes cell migration in mouse seminiferous epithelium

Reproductive Biology and Endocrinology, 2018
Background Spermatogenesis is a complex process involving the self-renewal and differentiation of spermatogonia into mature spermatids in the seminiferous tubules.
Yue Liu, Yanqin Hu, Li Wang, Chen Xu
doaj   +1 more source

Distribution of GFRA1-expressing spermatogonia in adult mouse testis

, 2012
In mice and other mammals, spermatogenesis is maintained by spermatogonial stem cells (SSCs), a cell population belonging to undifferentiated type A spermatogonia.
Margherita Grasso, BOITANI, Carla, de Rooij, Dirk G., Mario Stefanini, Dovere, Lisa, Carla Boitani, de Rooij, Dirk G, Elena Vicini, Dirk G. De Rooij, Andrea Fuso, Dirk G de Rooij, FUSO, ANDREA, Lisa Dovere, STEFANINI, Mario, VICINI, Elena, Grasso, Margherita   +15 more
core   +1 more source

Gene expression profiling of rat spermatogonia and Sertoli cells reveals signaling pathways from stem cells to niche and testicular cancer cells to surrounding stroma

BMC Genomics, 2011
Background Stem cells and their niches are studied in many systems, but mammalian germ stem cells (GSC) and their niches are still poorly understood.
Tachini Philippe, Zhang Yong, Vigier Michelle, Glauser Dominique, Ryser Stephan, Schlegel Werner, Durand Philippe, Irminger-Finger Irmgard   +7 more
doaj   +1 more source

The role of UCH-L1 in mouse progenitor spermatogonia

, 2016
To maintain fertility throughout the life of the adult male, the spermatogonial stem cell (SSC) population of the testis needs to achieve a balance between self-renewal and differentiation. The chemical, molecular and physical environment that supports
Alpaugh, Whitney
core   +1 more source