Results 101 to 110 of about 4,581 (187)

Effects of paternal ionizing radiation exposure on fertility and offspring's health

open access: yesReproductive Medicine and Biology
Purpose The intergenerational effects of ionizing radiation remain controversial. Extensive insights have been revealed for DNA mutations and cancer incidence in progeny, yet many of these results were obtained by immediate post‐radiation mating. However,
Jiaqun Li   +12 more
doaj   +1 more source

c-FlipL is expressed in undifferentiated mouse male germ cells

open access: yes, 2006
Apoptosis represents a fundamental process during fetal/post-natal testis development. Therefore pro- and anti-apoptotic proteins are essential to regulate testis physiology.
FILIPPINI, Antonio   +11 more
core   +1 more source

Geminin is required for mitotic proliferation of spermatogonia

open access: yes, 2012
Spermatogonial stem cells divide throughout life, maintaining their own population and giving rise to differentiated gametes. The unstable regulatory protein Geminin is thought to be one of the factors that determine whether stem cells continue to divide
Payne, Christopher J.   +3 more
core   +1 more source

Spermatogonia Differentiation Requires Retinoic Acid Receptor γ

open access: yes, 2012
International audienceVitamin A is instrumental to mammalian reproduction. Its metabolite, retinoic acid (RA), acts in a hormone-like manner through binding to and activating three nuclear receptor isotypes, RA receptor (RAR)α (RARA), RARβ, and RARγ ...
Mathilde Raverdeau   +18 more
core   +1 more source

SALL4 is expressed in undifferentiated spermatogonia in adult mouse seminiferous tubules.

open access: yes, 2013
Double immunohistochemistry of tissue sections was used to examine the localization of SALL4 in comparison to PLZF (A–D) and LIN28 (E–H), two known markers for undifferentiated spermatogonia.
Kathrin Gassei (103294)   +1 more
core   +1 more source

Target gene regulation by PLZF in mouse undifferentiated spermatogonia

open access: yes, 2014
This item is available only to currently enrolled UTSA students, faculty or staff. To download, navigate to Log In in the top right-hand corner of this screen, then select Log in with my UTSA ID.Spermatogonial stem cells (SSCs) are adult stem cells ...
Song, Yuntao
core  

Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation.

open access: yes, 2010
Microenvironments support the maintenance of stem cells and the growth of tumors through largely unknown mechanisms. While cell-autonomous chromatin modifications have emerged as important determinants for self-renewal and differentiation of stem cells ...
Jan Hermen Dannenberg   +11 more
core   +1 more source

Characteristics of JMJD3 null undifferentiated spermatogonia.

open access: yes, 2013
A. Relative expressions of SSC markers in control (F/-) and JMJD3 cKO (cKO) EPCAM-positive testicular cells were quantitatively analyzed. All of the expression levels were normalized to Gapdh expression.
Naoki Iwamori (229001)   +2 more
core   +1 more source

Loss of Vascular Endothelial Growth Factor A (VEGFA) Isoforms in the Testes of Male Mice Causes Subfertility, Reduces Sperm Numbers, and Alters Expression of Genes That Regulate Undifferentiated Spermatogonia

open access: yes, 2013
Vascular endothelial growth factor A (VEGFA) isoform treatment has been demonstrated to alter spermatogonial stem cell homeostasis. Therefore, we generated pDmrt1-Cre;Vegfa−/− (knockout, KO) mice by crossing pDmrt1-Cre mice to floxed Vegfa mice to test ...
Silversides, David W.   +27 more
core   +1 more source

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