Results 71 to 80 of about 4,581 (187)

The Transcriptional Cell Atlas of Testis Development in Sheep at Pre-Sexual Maturity

Current Issues in Molecular Biology, 2022
Sheep testes undergo a dramatic rate of development with structural changes during pre-sexual maturity, including the proliferation and maturation of somatic niche cells and the initiation of spermatogenesis.
Yi Wu, Tingting Guo, Jianye Li, Chune Niu, Weibo Sun, Shaohua Zhu, Hongchang Zhao, Guoyan Qiao, Mei Han, Xue He, Zengkui Lu, Chao Yuan, Jianlin Han, Jianbin Liu, Bohui Yang, Yaojing Yue   +15 more
doaj   +1 more source

Histological characterisation of gonadal sex differentiation in Malabar red snapper (Lutjanus malabaricus) for aquaculture advancement

Journal of Fish Biology, EarlyView.
Abstract The Malabar red snapper (Lutjanus malabaricus) is a high‐value tropical marine species receiving growing attention for aquaculture development in Singapore and Southeast Asia. At present, seed production relies primarily on uncontrolled mass spawning in sea cages, a practice that lacks consistency, biosecurity and control of genetic ...
Bing Liang, Dean R. Jerry, Joyce Koh, Purushothaman Kathiresan, Celestine Terence, Xueyan Shen, Grace Loo, Shubha Vij, Jose A. Domingos   +8 more
wiley   +1 more source

Sex‐Specific Gene Expression Ontogeny During Gonadal Development in Post‐Metamorphic Xenopus tropicalis

Molecular Reproduction and Development, Volume 93, Issue 4, April 2026.
Post‐metamorphic gonadal development in Xenopus tropicalis was analyzed through integrated morphometric, histological, and transcriptional approaches. Males showed upregulation of cyp17, amh, and amhr2, whereas females exhibited an increased aldh1a2 and ddx4.
Daniele Marini, Mauricio Roza, Cecilia Berg, Vanessa Brouard   +3 more
wiley   +1 more source

SM accelerates differentiation of undifferentiated Kit-negative spermatogonia.

, 2013
A) FACS analysis of total germ cells population from testes of 4dpp mice before (left panel) and after (right panel) removal of Kit positive cells. B) Western blot analysis of Kit, Stra8 and Scp3 expression in undifferentiated Kit negative cells at T0 ...
Manuela Pellegrini (367290), Giuseppina Claps (367291), Sara Di Siena (276168), Raffaele Geremia (318560), Pellegrino Rossi (367294), Silvia Di Cesare (367292), Paola Grimaldi (276175), Susanna Dolci (367293)   +7 more
core   +1 more source

Single-cell transcriptome analyses reveal critical regulators of spermatogonial stem cell fate transitions

BMC Genomics
Background Spermatogonial stem cells (SSCs) are the foundation cells for continual spermatogenesis and germline regeneration in mammals. SSC activities reside in the undifferentiated spermatogonial population, and currently, the molecular identities of ...
Shuang Li, Rong-Ge Yan, Xue Gao, Zhen He, Shi-Xin Wu, Yu-Jun Wang, Yi-Wen Zhang, Hai-Ping Tao, Xiao-Na Zhang, Gong-Xue Jia, Qi-En Yang   +10 more
doaj   +1 more source

Single-cell transcriptome analysis and in vitro differentiation of testicular cells reveal novel insights into male sterility of the interspecific hybrid cattle-yak

BMC Genomics, 2023
Background Interspecific hybridization plays vital roles in enriching animal diversity, while male hybrid sterility (MHS) of the offspring commonly suffered from spermatogenic arrest constitutes the postzygotic reproductive isolation.
TserangDonko Mipam, Xuemei Chen, Wangsheng Zhao, Peng Zhang, Zhixin Chai, Binglin Yue, Hui Luo, Jikun Wang, Haibo Wang, Zhijuan Wu, Jiabo Wang, Mingxiu Wang, Hui Wang, Ming Zhang, Hongying Wang, Kemin Jing, Jincheng Zhong, Xin Cai   +17 more
doaj   +1 more source

IL1R2 Marks and Sorts a Spermatogonial Stem Cell Population Critical for Restoring Spermatogenesis Upon Interruption in Mammals

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li, Zexuan Zhang, Zihan Xie, Cheng Jin, Zhipeng Wang, Changwei Yuan, Jun Zhu, Jielin Tang, Mengzhen Li, Dingfeng Zou, Xinyu Mang, Jun Liu, Dingyao Chen, Qi Geng, Yan Lu, Ning Zhang, Shiying Miao, Jing Peng, Kai Li, Wei Song   +19 more
wiley   +1 more source

Spermatogonial stem cell quest: nanos2, marker of a sub-population of undifferentiated A spermatogonia in trout testis

, 2014
Supplementary DataContinuous or cyclic production of spermatozoa throughout life in adult male vertebrate depends on a sub-population of undifferentiated germ cells acting as spermatogonial stem cells (SSCs).
Bellaïche, Johanna, Allemand, Isabelle, Lareyre, Jean-Jacques, Le Gac, Florence, Cauty, Chantal, Yano, Ayaka   +5 more
core   +1 more source

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, Volume 13, Issue 17, 23 March 2026.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source

Isolation of THY1+ Undifferentiated Spermatogonia from Mouse Postnatal Testes Using Magnetic-activated Cell Sorting (MACS)

Bio-Protocol, 2016
In mammals, homeostasis of many tissues rely on a subpopulation of cells, referred to as stem cells, to sustain an appropriate number of undifferentiated and differentiated cells.
Hung-Fu Liao, Joyce Kuo, Hsien-Hen Lin, Shau-Ping Lin   +3 more
doaj   +1 more source