Results 71 to 80 of about 213 (102)
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Reproductive Biology, 2023
Spermatogenesis is a continual process that relies on the activities of undifferentiated spermatogonia, which contain spermatogonial stem cells (SSCs) that serve as the basis of spermatogenesis. The gene expression pattern and molecular control of fate decisions of undifferentiated spermatogonia are not well understood.
Qi-En Yang, Hai-Ping Tao
exaly +3 more sources
Spermatogenesis is a continual process that relies on the activities of undifferentiated spermatogonia, which contain spermatogonial stem cells (SSCs) that serve as the basis of spermatogenesis. The gene expression pattern and molecular control of fate decisions of undifferentiated spermatogonia are not well understood.
Qi-En Yang, Hai-Ping Tao
exaly +3 more sources
THY1 as a reliable marker for enrichment of undifferentiated spermatogonia in the goat
Theriogenology, 2013Spermatogonial stem cells are unique cells of testes that can restore fertility upon transplantation into recipient testes. However, use of suitable markers for enrichment of these cells have important potential application. THY1, is an established conserved marker of spermatogonial stem cells in bovine, rodents, and primates, but there is no ...
Mojtaba Tahmoorespur +2 more
exaly +3 more sources
Analysis of putative biomarkers of undifferentiated spermatogonia in dog testis
Animal Reproduction Science, 2017Spermatogenesis begins after puberty and continues throughout a male's life, and is regulated by spermatogonial stem cells in the seminiferous tubules. Markers of male germ cells, including undifferentiated spermatogonia to fully developed spermatozoa have been identified in rodents, but not in dogs.
Hyuk Song, Ran Lee, Hyunjhung Jhun
exaly +3 more sources
The Anatomical Record, 1982
AbstractThe population of undifferentiated spermatogonia was studied in whole mounted seminiferous tubules of the Chinese hamster and the ram. The morphology of the differentiating spermatogonia in the ram is also described.The nuclear morphology of the undifferentiated spermatogonia was found to vary considerably.
Dirk G de Rooij
exaly +4 more sources
AbstractThe population of undifferentiated spermatogonia was studied in whole mounted seminiferous tubules of the Chinese hamster and the ram. The morphology of the differentiating spermatogonia in the ram is also described.The nuclear morphology of the undifferentiated spermatogonia was found to vary considerably.
Dirk G de Rooij
exaly +4 more sources
The Anatomical Record, 1987
AbstractThe topographical arrangement of the clones of Asingle, Apaired, and Aaligned (As, Apr, and Aal) spermatogonia on the basement membrane of seminiferous tubules of the Chinese hamster was studied. It was found that at least some of these clones are not distributed at random as clones of similar cell number were often seen in clusters. Areas were
de rooij, D. G., Janssen, J. M.
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AbstractThe topographical arrangement of the clones of Asingle, Apaired, and Aaligned (As, Apr, and Aal) spermatogonia on the basement membrane of seminiferous tubules of the Chinese hamster was studied. It was found that at least some of these clones are not distributed at random as clones of similar cell number were often seen in clusters. Areas were
de rooij, D. G., Janssen, J. M.
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Regulation of Cell Fate Decision of Undifferentiated Spermatogonia by GDNF
Science, 2000The molecular control of self-renewal and differentiation of stem cells has remained enigmatic. Transgenic loss-of-function and overexpression models now show that the dosage of glial cell line–derived neurotrophic factor (GDNF), produced by Sertoli cells, regulates cell fate decisions of undifferentiated spermatogonial cells that include ...
Meng, X. +13 more
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Regulation of the Differentiation of the Undifferentiated Spermatogonia
2000In the seminiferous epithelium of adult nonprimate mammals, so-called A-single (As) spermatogonia are the stem cells of spermatogenesis (1–3). Upon division of the As spermatogonia, the daughter cells either migrate away from each other and become two new stem cells, or the cells stay together becoming A-paired (Apr) spermatogonia connected by an ...
de Rooij, D.G. +6 more
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A Vasculature-Associated Niche for Undifferentiated Spermatogonia in the Mouse Testis
Science, 2007Mammalian spermatogenesis produces numerous sperm for a long period based on a highly potent stem cell system, which relies on a special microenvironment, or niche, that has not yet been identified. In this study, using time-lapse imaging of green fluorescent protein–labeled undifferentiated spermatogonia (A ...
Shosei, Yoshida +2 more
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Isolation of Undifferentiated Spermatogonia from Adult and Developing Mouse Testes
2023In the mammalian testis, the mitotic complements of spermatogenic cells are spermatogonia, including spermatogonial stem cells (SSCs) which form the basis of life-long spermatogenesis and male fertility. Thus, investigating spermatogonia and subdivisions thereof is essential to increase our understanding of male germline development and infertility ...
Vera, van Melis +2 more
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Lentiviral vector-mediated transduction of goat undifferentiated spermatogonia
Animal Reproduction Science, 2015Recent studies show that spermatogonial stem cells (SSCs) are able to colonize and form mature spermatozoa following transplantation into germ cell depleted testes of recipient males. Therefore, efficient ways for enrichment and gene transfer into SSCs provides a powerful tool for production of transgenic animals.
Hassan, Abbasi +7 more
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