Results 61 to 70 of about 213 (102)

Microgravity promotes differentiation and meiotic entry of postnatal mouse male germ cells.

PLoS ONE, 2010
A critical step of spermatogenesis is the entry of mitotic spermatogonia into meiosis. Progresses on these topics are hampered by the lack of an in vitro culture system allowing mouse spermatogonia differentiation and entry into meiosis. Previous studies
Manuela Pellegrini, Sara Di Siena, Giuseppina Claps, Silvia Di Cesare, Susanna Dolci, Pellegrino Rossi, Raffaele Geremia, Paola Grimaldi   +7 more
doaj   +1 more source

A single recombinant follicle stimulating hormone injection promotes spermatogenesis onset in a proportion of juvenile flathead grey mullet Mugil cephalus

Aquaculture Reports
Recombinant gonadotropins have proven effective in overcoming the reproductive dysfunction observed in adult captive flathead grey mullet Mugil cephalus.
Rosa Zupa, Giancarlo Cerrud-Barría, Caterina Varvara, Ignacio Giménez, Deborah Maria Del Frassino, Adriana Lo Giudice, Gianluca Ventriglia, Valeria Buonfrate, Aldo Corriero, Neil Duncan   +9 more
doaj   +1 more source

Expression of transcriptional factor EB (TFEB) in differentiating spermatogonia potentially promotes cell migration in mouse seminiferous epithelium

Reproductive Biology and Endocrinology, 2018
Background Spermatogenesis is a complex process involving the self-renewal and differentiation of spermatogonia into mature spermatids in the seminiferous tubules.
Yue Liu, Yanqin Hu, Li Wang, Chen Xu
doaj   +1 more source

Gene expression profiling of rat spermatogonia and Sertoli cells reveals signaling pathways from stem cells to niche and testicular cancer cells to surrounding stroma

BMC Genomics, 2011
Background Stem cells and their niches are studied in many systems, but mammalian germ stem cells (GSC) and their niches are still poorly understood.
Tachini Philippe, Zhang Yong, Vigier Michelle, Glauser Dominique, Ryser Stephan, Schlegel Werner, Durand Philippe, Irminger-Finger Irmgard   +7 more
doaj   +1 more source

Effects of paternal ionizing radiation exposure on fertility and offspring's health

Reproductive Medicine and Biology
Purpose The intergenerational effects of ionizing radiation remain controversial. Extensive insights have been revealed for DNA mutations and cancer incidence in progeny, yet many of these results were obtained by immediate post‐radiation mating. However,
Jiaqun Li, Juan Liu, Yanye Zhang, Hong Qiu, Junyan Zheng, Jinglei Xue, Jiani Jin, Feida Ni, Chunxi Zhang, Chuan Chen, Xiao Sun, Huiquan Wang, Dan Zhang   +12 more
doaj   +1 more source

Effects of neonatal hypothyroidism on testicular development and undifferentiated spermatogonia in prepubertal rats

Andrology
Abstract Background Thyroid hormones play a key role in testicular development, particularly in the regulation of Sertoli cell proliferation and differentiation. While congenital hypothyroidism is common and treatable, the effects of thyroid hormone insufficiency on early testicular development
Matsumoto, Daisuke, Mizuno, Kentaro, Nishio, Hidenori, Kamisawa, Hideyuki, Sakata, Takuya, Kato, Taiki, Nakane, Akihiro, Kurokawa, Satoshi, Maruyama, Tetsuji, Hayashi, Yutaro, Yasui, Takahiro   +10 more
openaire   +3 more sources

A Novel Cultivation System for Germ Cell Proliferation and Sustaining Whole Testicular Niche

Advanced Science
Childhood cancer treatments often impair male fertility due to gonadotoxic effects. While in vitro culture of prepubertal testis tissue offers a potential solution to preserve fertility, producing sufficient sperm remains a major barrier. To address this,
Yu Xia, Xiaoxuan Zhang, Bohang Zhang, Minhui Lu, Qing Cheng, Li Liu, Lifang Shi, Yiqiang Cui, Dingdong Chen, Laihua Li, Xuejiang Guo, Jingtao Guo, Jiahao Sha, Yuanjin Zhao, Yan Yuan   +14 more
doaj   +1 more source

Undifferentiated spermatogonia modulate their behavior via the expression of basement membrane protein laminin

Biology of Reproduction
Abstract In the mouse testis, spermatogonial stem cells (SSCs) are sparsely distributed and migrate along the basement membrane of seminiferous tubules. Although the basement membrane is generally thought to be formed by surrounding somatic cells, whether SSCs also produce basement membrane proteins and, if so, whether SSC-produced ...
Yusuke Kawabe, Saya Yamada, Yuichi Shima, Kentaro Tanemura, Shosei Yoshida, Kenshiro Hara   +5 more
openaire   +2 more sources

Safeguarding genetic resources of curassow through cryopreservation and transplantation of post-mortem recovered testicular cells into recipient roosters

Theriogenology Wild
Cryopreservation and transplantation of testicular cells (TCs), especially spematogonial stem cells (SSCs), offers a new perspective for the genetic rescue of birds since traditional biobanking using semen and eggs are either inefficient or impractical ...
Marcel Henrique Blank, Marcelo Demarchi Goissis, Roberto Motta de Avelar Azeredo, Luís Fábio Silveira, Ricardo José Garcia Pereira   +4 more
doaj   +1 more source

CDH1 Is a Specific Marker for Undifferentiated Spermatogonia in Mouse Testes1 [PDF]

Biology of Reproduction, 2007
Masutaka Tokuda, Yuzo Kadokawa, Hiroki Kurahashi, Tohru Marunouchi   +3 more
openaire   +1 more source