Results 41 to 50 of about 4,581 (187)
Cell Death and Disease, 2021 Spermatogonia transit-amplifying (TA) divisions are crucial for the differentiation of germline stem cell daughters. However, the underlying mechanism is largely unknown.
Jun Yu +9 more
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Recent Update on Retinoic Acid-Driven Initiation of Spermatogonial Differentiation
Frontiers in Cell and Developmental Biology, 2022 Germ cells (Gc) propagate the genetic information to subsequent generations. Diploid (2n) Gc get transformed to specialized haploid (n) gametes by mitotic and meiotic divisions in adult gonads.
Indrashis Bhattacharya +5 more
doaj +1 more source
Andrology, 2023 AbstractBackgroundAcetaminophen and ibuprofen are widely administered to babies due to their presumed safety as over‐the‐counter drugs. However, no reports exist on the effects of cyclooxygenase inhibitors on undifferentiated spermatogonia and spermatogonial stem cells.
Amy Tran‐Guzman +2 more
openaire +2 more sources
Nutrient restriction synergizes with retinoic acid to induce mammalian meiotic initiation in vitro
Nature Communications, 2021 Retinoic acid is necessary but not sufficient to induce meiosis. Here, the authors use primary mouse undifferentiated spermatogonia culture to show that nutrient restriction, an inducer of yeast meiosis, combined with retinoic acid induces meiotic gene ...
Xiaoyu Zhang +2 more
doaj +1 more source
Mitochondrial fusion is required for spermatogonial differentiation and meiosis
eLife, 2019 Differentiating cells tailor their metabolism to fulfill their specialized functions. We examined whether mitochondrial fusion is important for metabolic tailoring during spermatogenesis.
Grigor Varuzhanyan +6 more
doaj +1 more source
Spermatogonial stem cell niche and spermatogonial stem cell transplantation in zebrafish. [PDF]
PLoS ONE, 2010 BACKGROUND: Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis, and reside within a specific microenvironment in the testes called "niche" which regulates stem cell properties, such as, self-renewal, pluripotency, quiescence and their
Rafael Henrique Nóbrega +5 more
doaj +1 more source
Conditions for Long-Term Culture of Cattle Undifferentiated Spermatogonia
Biology of Reproduction, 2016 Continual and robust spermatogenesis relies on the actions of an undifferentiated spermatogonial population that contains stem cells. A remarkable feature of spermatogonial stem cells (SSCs) is the capacity to regenerate spermatogenesis following isolation from a donor testis and transplantation into a permissive recipient testis.
Melissa J, Oatley +4 more
openaire +2 more sources
, 2020 Differentially expressed genes associated with undifferentiated spermatogonia between cattleyaks (CY) and yaks (YK).
Shixin Wu (2090413) +8 more
core +1 more source
THY1 is a conserved marker of undifferentiated spermatogonia in the pre-pubertal bull testis [PDF]
Reproduction, 2010 Abstract The undifferentiated spermatogonial population consists of stem and progenitor germ cells which function to provide the foundation for spermatogenesis. The stem cell component, termed spermatogonial stem cells (SSCs), is capable of self-renewal and differentiation.
Suzanne C, Reding +3 more
openaire +2 more sources
Gonadal development in scorpion mud‐turtles, Kinosternon scorpioides, in a controlled environment
The Anatomical Record, EarlyView.Stage 20 was identified as the critical point for gonadal differentiation in Kinosternon scorpioides, providing key insights into sex determination. These findings enhance conservation strategies by supporting reproductive management and population viability in both in situ and ex situ programs. Abstract Research on gonadal development including sexual
Brenda Braga +4 more
wiley +1 more source