Results 11 to 20 of about 486 (156)

The landscape of recurrent spontaneous abortion registered on clinical trials.gov [PDF]

Frontiers in Endocrinology
ObjectiveRecurrent spontaneous abortion (RSA) presents a significant challenge in the field of reproductive medicine, as effective treatments remain limited despite extensive research efforts.
Xiaoling Zhou, Fan Lai, Wei Chen, Congrong Zhou, Yi Deng, Tao Wang, Shasha Xing, Haoyang Diao, Mi Tang, Wenmei Guo, Erdan Luo   +10 more
doaj   +5 more sources

Prediction of Unexplained Recurrent Miscarriages Using Thromboelastography [PDF]

International Journal of Women's Health
Jinjin Xu,1– 3,* Yan Yang,1– 3,* Guixue Guan,1– 3,* Yuan Gao,1– 3 Qian Sun,1– 3 Guangwei Yuan,4 Xiaozuo Zhang,1– 3 Jingyun Yang,5,6 Wen Yang,1– 3 Zuobin Zhu,7 Conghui Han8,9 1Department of Gynecology, The First People’s Hospital of ...
Xu J, Yang Y, Guan G, Gao Y, Sun Q, Yuan G, Zhang X, Yang J, Yang W, Zhu Z, Han C   +10 more
doaj   +5 more sources

Beyond Immune Balance: The Pivotal Role of Decidual Regulatory T Cells in Unexplained Recurrent Spontaneous Abortion [PDF]

Journal of Inflammation Research
Qing-Hui Li,1,2 Qiu-Yan Zhao,1 Wei-Jing Yang,1 Ai-Fang Jiang,2 Chun-E Ren,2 Yu-Han Meng2 1School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, 261021, People’s Republic of China; 2Center of Reproductive Medicine, Affiliated
Li QH, Zhao QY, Yang WJ, Jiang AF, Ren CE, Meng YH   +5 more
doaj   +5 more sources

Association between Functional Polymorphisms of Foxp3 Gene and the Occurrence of Unexplained Recurrent Spontaneous Abortion in a Chinese Han Population [PDF]

Clinical and Developmental Immunology, 2012
Unexplained recurrent spontaneous abortion (URSA) is an alloimmune disease associated with the failure of fetal-maternal immunologic tolerance in which the regulatory T lymphocytes (Treg) play a pivotal role. It is well known that Forkhead box P3 (Foxp3)
Zaigui Wu, Zeshan You, Cai Zhang, Zhuyu Li, Xiumei Su, Xiuming Zhang, Yinguang Li   +6 more
doaj   +2 more sources

Moderating role of blood inflammatory markers in the vaginal microbiota-fibrinogen relationship in URSA-affected women [PDF]

Scientific Reports
The etiology and pathogenic mechanisms underlying recurrent spontaneous abortion (RSA) are poorly understood. Specifically, patients with unexplained recurrent spontaneous abortion (URSA) frequently exhibit dysbiosis of the vaginal microbiota and ...
Hongyan Xu, Yanqun Liu, Tianzi Zang, Xiaoxiao Fan, Yanan Cao, Shanshan Ni, Siqi Yang, Jinbing Bai, Zaidi Gui   +8 more
doaj   +2 more sources

HK2-driven histone H3K18 lactylation promotes stromal cell senescence and decidualization deficiency in URSA via CUX1-mediated SASP factor transcription [PDF]

Cellular & Molecular Biology Letters
Background Unexplained recurrent spontaneous abortion (URSA) is characterized by defective endometrial stromal cell decidualization, with cellular senescence emerging as a key contributor.
Xiaoxuan Zhao, Yang Zhao, Yuepeng Jiang, Yiming Ma, Jing Ma, Hongli Zhao, Xiaoling Feng   +6 more
doaj   +2 more sources

KLF4 regulates trophoblast function and associates with unexplained recurrent spontaneous abortion [PDF]

Journal of Translational Medicine
Background Recurrent spontaneous abortion (RSA) is defined as two or more consecutive spontaneous abortions before 20 weeks with the same spouse [1].
Yiling Tan, Jiayu Wang, Chunming Liu, Shujuan Wu, Mengqi Zhou, Yan Zhang, Tailang Yin, Jing Yang   +7 more
doaj   +2 more sources

The Immunomodulatory Effects of Human Amniotic Epithelial Cells on Peripheral Blood Natural Killer T (NKT) Cells in Women with Unexplained Recurrent Spontaneous Abortion (URSA)

مجله دانشکده پزشکی اصفهان, 2018
Background: Unexplained recurrent spontaneous abortion (URSA) is the most common immunological complication during pregnancy. The evidence of in-vitro assays has shown that immune cells are responsible for embryotoxicity.
Fahimeh Khadem, Nafiseh Esmaeil, Abbas Rezaei, Behnaz Khani   +3 more
doaj   +2 more sources

Changes and clinical significance of peripheral blood helper T lymphocyte and natural killer (NK) cells in unexplained recurrent spontaneous abortion (URSA) patients after abortion and successful pregnancy

Clinical and Experimental Obstetrics and Gynecology, 2015
This study aims to investigate the number changes and the clinical significance of the peripheral blood T lymphocyte subsets and NK (natural killer) cells in unexplained recurrent spontaneous abortion (URSA) patients before and after abortion, as well as after successful pregnancy.Thirty-nine URSA patients (URSA-abortion group), among who 22 patients ...
L Y, Zhu, X, Chen, Z Z, Xu, L, Xu, T, Mao, H, Zhang   +5 more
exaly   +3 more sources

Efficacy of mesenchymal stromal cells in the treatment of unexplained recurrent spontaneous abortion in mice: An analytical and systematic review of meta-analyses. [PDF]

PLoS ONE, 2023
ObjectivesUnexplained recurrent spontaneous abortion (URSA) remains an intractable reproductive dilemma due to the lack of understanding of the pathogenesis.
Xiaoxuan Zhao, Yijie Hu, Wenjun Xiao, Yiming Ma, Dan Shen, Yuepeng Jiang, Yi Shen, Suxia Wang, Jing Ma   +8 more
doaj   +2 more sources