Results 41 to 50 of about 486 (156)

Study of methyl transferase (G9aMT) and methylated histone (H3-K9) expressions in unexplained recurrent spontaneous abortion (URSA) and normal early pregnancy [PDF]

MHR: Basic science of reproductive medicine, 2011
We investigated the expression of methyl transferase G9a and methylated histone H3-K9 in fresh human decidual/endometrial tissue of 12 normal early pregnancies and 15 unexplained recurrent spontaneous abortions (URSA). The samples were obtained through dilatation and curettage and collected as per strict inclusion-exclusion criteria.
Nishat, Fatima, S H, Ahmed, Sudha, Salhan, S M F, Rehman, Jatinder, Kaur, M, Owais, Shyam S, Chauhan   +6 more
openaire   +2 more sources

Re‐evaluation of the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs

EFSA Journal, Volume 21, Issue 4, April 2023., 2023
Abstract In 2015, EFSA established a temporary tolerable daily intake (t‐TDI) for BPA of 4 μg/kg body weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the risks to public health from the presence of BPA in foodstuffs and to establish a tolerable daily intake (TDI). For this re‐evaluation, a pre‐established protocol was
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Andrew Chesson, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Vittorio Silano (until 21 December 2020†), Inger‐Lise Steffensen, Christina Tlustos, Laurence Vernis, Holger Zorn, Monika Batke, Margherita Bignami, Emanuela Corsini, Rex FitzGerald, Ursula Gundert‐Remy, Thorhallur Halldorsson, Andrew Hart, Evangelia Ntzani, Eugenio Scanziani, Henri Schroeder, Beate Ulbrich, Dina Waalkens‐Berendsen, Detlef Woelfle, Zainab Al Harraq, Katleen Baert, Maria Carfì, Anna F Castoldi, Cristina Croera, Henk Van Loveren   +37 more
wiley   +1 more source

The Progress of Research on Genetic Factors of Recurrent Pregnancy Loss

Genetics Research , Volume 2023, Issue 1, 2023., 2023
Recurrent pregnancy loss (RPL) is both mental and physical health problem affecting about 1–5% of women of childbearing age. The etiology of RPL is complex, involving chromosomal abnormalities, autoimmune diseases, metabolic disorders, and endometrial dysfunction. The causes of abortion are still unknown in more than 50% of these cases.
Qinlan Li, Shuting Chen, Xinyi Dong, Sen Fu, Tianyu Zhang, Weiwei Zheng, Yonghong Tian, Donghui Huang, Nadeem Sheikh   +8 more
wiley   +1 more source

Key Gene and Functional Pathways Identified in Unexplained Recurrent Spontaneous Abortion Using Targeted RNA Sequencing and Clinical Analysis

Frontiers in Immunology, 2021
Identifying the mechanisms underlying unexplained recurrent spontaneous abortion (URSA) can help develop effective treatments. This study provides novel insights into the biological characteristics and related pathways of differentially expressed genes ...
Heng Gu, Longyu Li, Mengxuan Du, Mengxuan Du, Hang Xu, Hang Xu, Mengge Gao, Mengge Gao, Xiaohua Liu, Xiangcai Wei, Xiangcai Wei, Xingming Zhong, Xingming Zhong   +12 more
doaj   +1 more source

Efficacy of intravenous immunoglobulin in the treatment of recurrent spontaneous abortion: A systematic review and meta‐analysis

American Journal of Reproductive Immunology, Volume 88, Issue 5, November 2022., 2022
Abstract Objective We aimed to evaluate the efficacy of IVIG in the treatment with patients with recurrent spontaneous abortion (RSA). Methods PubMed, Embase, Web of science, Cochrane library were searched for randomized controlled (RCTs) about effect of IVIG on RSA from inception to August 20, 2021.
Yimin Shi, Dongmei Tan, Baozhen Hao, Xiurong Zhang, Wei Geng, Yayu Wang, Jianyi Sun, Yue Zhao   +7 more
wiley   +1 more source

[Retracted] Study on the Relationship between Unexplained Recurrent Abortion and HLA‐DQ Gene Polymorphism

Computational Intelligence and Neuroscience, Volume 2022, Issue 1, 2022., 2022
Objective. The study aimed to investigate the relationship between human leukocyte antigen (HLA‐DQB1) gene variants and recurrent miscarriage. Methods. HLA‐DQ gene polymorphisms (PCR‐SSP) were detected in 50 couples with recurrent miscarriage (URSA group) and 30 couples with normal births (control group) using sequence‐specific primer‐guided polymerase
Jie Tang, Jichao Zhu, Longwen Shu, Xiaohong Huang, Siming Ma, N. Rajesh   +5 more
wiley   +1 more source

Clinical predictive value of pre-pregnancy tests for unexplained recurrent spontaneous abortion: a retrospective study. [PDF]

Front Med (Lausanne)
IntroductionEarly prediction and intervention are crucial for the prognosis of unexplained recurrent spontaneous abortion (uRSA). The main purpose of this study is to establish a risk prediction model for uRSA based on routine pre-pregnancy tests, in ...
Wang J, Li D, Guo Z, Ren Y, Wang L, Liu Y, Kang K, Shi W, Huang J, Liao S, Hao Y.   +10 more
europepmc   +3 more sources

Immunogenetic Role of IL17A Polymorphism in the Pathogenesis of Recurrent Miscarriage [PDF]

, 2022
Interleukin-17A (IL17A) is a proinflammatory cytokine and is assumed to play an important role in fetal rejection. In order to evaluate the potential role of IL17A polymorphism in the pathogenesis of recurrent miscarriage (RM), serum IL17A levels were ...
Ali, Md Niamat, Ali, Shafat, Banday, Mujeeb Zafar, Majid, Sabhiya   +3 more
core   +2 more sources

Considerations on inhibition of IL‐23 in psoriatic women of childbearing potential

Dermatologic Therapy, Volume 34, Issue 3, May/June 2021., 2021
Abstract Lack of safety data on pregnant women determines difficulty in choosing the correct biologic agent to treat psoriasis in women of childbearing potential. Studies have postulated a role of IL‐23 in unexplained recurrent spontaneous abortions. This gives rise to consideration about use of anti‐IL‐23 drugs in treatment of psoriasis in women of ...
Roberto Russo, Giulia Gasparini, Emanuele Cozzani, Martina Burlando, Aurora Parodi   +4 more
wiley   +1 more source

[Retracted] Influence of Bushen Tiaochong Cycle Therapy on Th1/Th2 Deviation, Sex Hormone Level, and Pregnancy Outcome of Alloimmune Recurrent Spontaneous Abortion

Evidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021
Objective. To analyze the influence of Bushen Tiaochong cycle therapy on Th1/Th2 deviation, sex hormone level, and pregnancy outcome of alloimmune recurrent spontaneous abortion (RSA). Methods. From August 2018 to April 2020, 130 patients with alloimmune RSA who met the inclusion criteria were randomly divided into the control group (n = 65) and the ...
Peng Wang, Guilin Jiang, Wenjuan Ju, Yaping Cai, Jinrong Wang, Feihua Wu, Songwen Tan   +6 more
wiley   +1 more source