Results 201 to 210 of about 167,289 (308)

Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury

, 2010
Maryla Krajewska, Lucy Xu, Wenjie Xu, Stan Krajewski, Christina Kress, Jiankun Cui, Li Yang, Fumitoshi Irie, Yu Yamaguchi, Stuart A. Lipton, John C. Reed   +10 more
openalex   +2 more sources

Wirelessly Powered Soft Magnetic Robot with Microneedle for Electrical Stimulation and Drug Delivery

Advanced Intelligent Systems, EarlyView.
A wirelessly powered soft magnetic robot integrates microneedles to enable dual functions: electrical stimulation (86.7% efficiency at 6 cm, tunable 0–20 V voltage, 0.4–50 ms pulses) and drug delivery. It switches surfaces via magnetic fields for gastrointestinal tract locomotion and treatment, with in vitro validation in fresh pig gut showing ...
Song Zhao, Liwen Zhang, Shengbin Zhang, Botao Ma, Meng Wang, Yipan Zuo, Xinzhao Zhou, Xueshan Jing, Huawei Chen   +8 more
wiley   +1 more source

Targeting the unfolded protein response for cancer therapy: mitigating tumor adaptation and immune suppression. [PDF]

Biomark Res
Unal B, Saatcioglu F.
europepmc   +1 more source

Identification of HYPK-Interacting Proteins Reveals Involvement of HYPK in Regulating Cell Growth, Cell Cycle, Unfolded Protein Response and Cell Death

, 2012
Kamalika Roy Choudhury, Swasti Raychaudhuri, Nitai P. Bhattacharyya   +2 more
openalex   +2 more sources

Mechanisms of Mitochondrial Toxicity and Cytotoxicity Caused by Pseudomonas aeruginosa Pyocyanin in Human Nasal Epithelial Cells

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson, April Park, Yobouet Ines Kouakou, Zoey A. Miller, Nabil F. Darwich, Nithin D. Adappa, James N. Palmer, Ryan M. Carey, Robert J. Lee   +8 more
wiley   +1 more source

Hijacking the unfolded protein response (UPR) pathway: Balancing viral infection and host cell survival. [PDF]

J Biol Chem
Chen H, Liu D, Hua J, Wu M, Hua Y, Feng C, He Z, Moffett P, Zhang K.   +8 more
europepmc   +1 more source

Establishment of a mouse model of TMAO‐induced cardiac injury and application of MICT intervention

Animal Models and Experimental Medicine, EarlyView.
This study aims to explore the establishment of an animal model of cardiac injury induced by trimethylamine‐N‐oxide (TMAO), a metabolite secreted by gut microorganisms, and to investigate its application in moderate‐intensity continuous training (MICT) intervention.
Zhongping Xie, Hong Zou, Lijing Gong, Minghui Lin, Caihua Huang   +4 more
wiley   +1 more source

Phosphatidylcholine coordinates ER-autonomous and ER-nonautonomous adaptations to unfolded protein response dysfunction. [PDF]

J Biol Chem
Tong H, Li W, Yuan P, Wang X, Pang S, Tang H.   +5 more
europepmc   +1 more source

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

, 2003
Ann–Hwee Lee, Neal N. Iwakoshi, Laurie H. Glimcher   +2 more
openalex   +1 more source

Leukocyte mRNA sequencing reveals unfolded protein response activation in severe heat stroke in Japan. [PDF]

Front Cell Dev Biol
Nomura Y, Oda S, Matsumoto H, Togami Y, Shimazaki J, Okuzaki D, Ogura H, Oda J.   +7 more
europepmc   +1 more source