Results 211 to 220 of about 1,143,124 (339)

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

open access: yesHepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam   +10 more
wiley   +1 more source

Perk is essential for translational regulation and cell survival during the unfolded protein response.

open access: yesMolecules and Cells, 2000
H. Harding   +4 more
semanticscholar   +1 more source

Bursting the unfolded protein response accelerates axonal regeneration

open access: yesNeural Regeneration Research, 2016
Maritza Oñate   +2 more
doaj   +1 more source

Brucella Omp25 activates the unfolded protein response to promote intracellular proliferation and inflammation. [PDF]

open access: yesJ Biol Chem
Yang JK   +9 more
europepmc   +1 more source

Nrf2-dependent survival signaling during the unfolded protein response

open access: yes, 2005
The ability of cells to maintain homeostatic control in the face of cellular insults is critical in all aspects of multicellular life. The endoplasmic reticulum is exquisitely poised to sense and respond to many different cellular stresses that result ...
Cullinan, Sara B
core  

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