Results 221 to 230 of about 1,143,124 (339)

Unfolded Protein Response [PDF]

, 2020
openaire   +1 more source

Unraveling the role of mitochondrial unfolded protein response in colorectal cancer. [PDF]

Biochem Biophys Rep
Shi J, Wu L, Tian C, Chen H.
europepmc   +1 more source

Activation of unfolded protein response pathways promotes keratinocyte differentiation and ameliorates psoriasis phenotypes. [PDF]

Cell Stress Chaperones
Zhang Z, Tan M, Liu X, Wang W, Chen X, Peng C, Zhao S, Wu L.   +7 more
europepmc   +1 more source

CTRP3 alleviates neuropathic pain by improving mitochondrial biogenesis and mitochondrial unfolded protein response via spinal SIRT1 in rats. [PDF]

Int J Mol Med
Liu T, Zhang L, Mei W.
europepmc   +1 more source

Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus

Animal Research and One Health, EarlyView.
The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary, Nidhishree N. S, Rakesh Kumar Pundir, Muhasin Asaf V. N, Anamika Mishra, Ashwin Ashok Raut, Megha Agarwal, Amod Kumar   +7 more
wiley   +1 more source

bZIP factors of the Unfolded Protein Response interact with PIF4 to promote thermomorphogenesis. [PDF]

Nat Commun
Zhang D, Xu H, Chua NH.
europepmc   +1 more source

Indole‐3‐Acetic Acid Protects Bovine Hepatocytes Against Palmitic Acid‐Induced Lipid Accumulation and ER Stress Through SIRT3

Animal Research and One Health, EarlyView.
Cows with ketosis during the perinatal period often experience damage to the liver, a core metabolic organ, thereby exacerbating the disease's inherent vicious cycle. This study indicates that serum 3‐IAA concentrations were reduced in ketotic cows and show a significant negative correlation with hepatic TG content.
Dandan Qi, Chenchen Zhao, Guiying Li, Jinxia Li, Menglin Liu, Fanrong Kong, Enzhu Li, Jie Gao, Wenqi Liao, Akos Kenez, Wenwen Gao, Yuxiang Song, Xiliang Du, Guowen Liu, Xinwei Li, Lin Lei   +15 more
wiley   +1 more source

The Unfolded Protein Response-Novel Mechanisms, Challenges, and Key Considerations for Therapeutic Intervention. [PDF]

Cancers (Basel)
Mai PMQ, Truong TA, Samala SK, Lakshmisha BM, Biswal P, Koushki K, Mallepaddi PC, Vijay G, Krishnan S.   +8 more
europepmc   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

The Unfolded Protein Response in Sarcomas: From Proteostasis to Therapy Resistance. [PDF]

Cancers (Basel)
Ilieva E, Avnet S, Baldini N, Cortini M.
europepmc   +1 more source