Results 231 to 240 of about 80,560 (274)

Advances on Albumin‐Based Carriers for Anticancer Drug Delivery

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou   +4 more
wiley   +1 more source

Emerging Strategies for Platelet‐Modified Nanoparticles in Targeted Tumor Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights innovative strategies using platelet‐modified nanoparticles to target tumors more precisely. By mimicking platelet functions, these biomimetic carriers improve tumor homing, enhance drug delivery, and reduce immune clearance.
Chunyu Bai   +5 more
wiley   +1 more source

AIE−Active BODIHYs Based on Benzothiazole–Hydrazone Chelates and Their Artificial Light Harvesting and Reversible Mechanochromic Behavior

open access: yesChemistry – An Asian Journal, EarlyView.
An exceptionally effective artificial light‐harvesting system (ALHS) in an aqueous environment, employing energy transfer via FRET, has been successfully engineered. Synthesized ligands L1‐L3 and BODIHYs (B1‐B3) have been thoroughly characterized by various techniques (1H, 13C, 11B, 19F NMR, ESIMS, UV/Vis, and fluorescence).
Nikhil Kumar Singh   +2 more
wiley   +1 more source

From Genome to Geroscience: How DNA Damage Shapes Systemic Decline

open access: yesBioEssays, EarlyView.
Persistent DNA damage triggers systemic secretory responses including damage‐associated molecular patterns (DAMPs), the senescence‐associated secretory phenotype (SASP), and extracellular vesicles (EVs). This non‐cell‐autonomous signaling disrupts intercellular communication, driving organism‐wide dysfunction and aging, and offering new therapeutic ...
Athanasios Siametis, George A. Garinis
wiley   +1 more source

Defective Ribosome Recycling: A Bridge Between Translation Fidelity, Organelle Dysfunction, and Diseases

open access: yesBioEssays, EarlyView.
The Role of Ribosome Recycling in Human Diseases This diagram highlights how disruptions in ribosome translation and recycling can negatively impact cellular and organismal health. Usually, these processes operate efficiently to maintain cellular protein homeostasis.
Foozhan Tahmasebinia, Zhihao Wu
wiley   +1 more source

The Missing Link: Connecting Cultivation Conditions and Refolding Performance via Inclusion Body Biophysical Properties

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Inclusion bodies (IBs) frequently form during the expression of heterologous proteins in Escherichia coli and are therefore important in pharmaceutical production. While it is accepted that cultivation conditions affect cultivation performance, the link to refolding performance remains unexplored. This study proposes that this interplay relies,
Matthias Rüdt   +6 more
wiley   +1 more source

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