Results 21 to 30 of about 12,490 (237)

Octanol-assisted liposome assembly on chip

Nature Communications, 2016
A broad application of liposomes calls for high throughout techniques to produce them in a controlled and fast manner. Here, Deshpande et al. show a microfluidic approach using alcohol-based lipid-carrying material to generate monodisperse and ...
Siddharth Deshpande, Yaron Caspi, Anna E. C. Meijering, Cees Dekker   +3 more
doaj   +1 more source

Unilamellar liposomes made with the French pressure cell: a simple preparative and semiquantitative technique

Journal of Lipid Research, 1980
A simple, rapid, and almost quantitative technique is described for the preparation of 1-40 ml of homogeneous unilamellar liposomes from dilute or concentrated aqueous suspensions of egg phosphatidylcholine.
R L Hamilton, Jr, J Goerke, L S Guo, M C Williams, R J Havel   +4 more
doaj   +1 more source

Cell-Penetrating Peptides-Based Liposomal Delivery System Enhanced Immunogenicity of Peptide-Based Vaccine against Group A Streptococcus

Vaccines, 2021
Peptide-based vaccine development represents a highly promising strategy for preventing Group A Streptococcus (GAS) infection. However, these vaccines need to be administered with the help of a delivery system and/or immune adjuvant.
Jieru Yang, Farrhana Firdaus, Armira Azuar, Zeinab G. Khalil, Nirmal Marasini, Robert J. Capon, Waleed M. Hussein, Istvan Toth, Mariusz Skwarczynski   +8 more
doaj   +1 more source

Small cationic DDA:TDB liposomes as protein vaccine adjuvants obviate the need for TLR agonists in inducing cellular and humoral responses.

PLoS ONE, 2012
Most subunit vaccines require adjuvants in order to induce protective immune responses to the targeted pathogen. However, many of the potent immunogenic adjuvants display unacceptable local or systemic reactogenicity.
Anita Milicic, Randip Kaur, Arturo Reyes-Sandoval, Choon-Kit Tang, Jared Honeycutt, Yvonne Perrie, Adrian V S Hill   +6 more
doaj   +1 more source

Thermophoretic migration of vesicles depends on mean temperature and head group chemistry

Nature Communications, 2017
Thermal gradients are shown to provide a robust and chemically specific driving force to liposomes. Here the authors show controlled direction of migration of unilamellar lipid vesicles by varying the temperature in the suspension and the exposed polar ...
Emma L. Talbot, Jurij Kotar, Lucia Parolini, Lorenzo Di Michele, Pietro Cicuta   +4 more
doaj   +1 more source

Effects of Lipid Composition and Solution Conditions on the Mechanical Properties of Membrane Vesicles

Membranes, 2015
The mechanical properties of cell-sized giant unilamellar liposomes were studied by manipulating polystyrene beads encapsulated within the liposomes using double-beam laser tweezers.
Nobuhiko Kato, Akihiko Ishijima, Takehiko Inaba, Fumimasa Nomura, Shuichi Takeda, Kingo Takiguchi   +5 more
doaj   +1 more source

Les liposomes : description, fabrication et applications [PDF]

Biotechnologie, Agronomie, Société et Environnement, 2004
Liposomes: description, preparation and applications. Liposomes are spherical vesicles with a diameter ranging from 20 nm to a few thousands nm. These vesicles consist of one or several bilayers which separate an intravesicular from an external medium.
Brasseur R., Thomas A., Flore C., Lorin A.   +3 more
doaj  

Formation of Giant Unilamellar Proteo-Liposomes by Osmotic Shock [PDF]

Langmuir, 2015
Giant unilamellar vesicles (GUVs), composed of a phospholipid bilayer, are often used as a model system for cell membranes. However, the study of proteo-membrane interactions in this system is limited as the incorporation of integral and lipid-anchored proteins into GUVs remains challenging.
Motta, Isabelle, Gohlke, Andrea, Adrien, Vladimir, Li, Feng, Gardavot, Hélène, Rothman, James, Pincet, Frederic   +6 more
openaire   +3 more sources

Naja naja oxiana Cobra Venom Cytotoxins CTI and CTII Disrupt Mitochondrial Membrane Integrity: Implications for Basic Three-Fingered Cytotoxins. [PDF]

PLoS ONE, 2015
Cobra venom cytotoxins are basic three-fingered, amphipathic, non-enzymatic proteins that constitute a major fraction of cobra venom. While cytotoxins cause mitochondrial dysfunction in different cell types, the mechanisms by which cytotoxins bind to ...
Sardar E Gasanov, Indira H Shrivastava, Firuz S Israilov, Aleksandr A Kim, Kamila A Rylova, Boris Zhang, Ruben K Dagda   +6 more
doaj   +1 more source

Analysis of the shape fluctuations of reconstituted membranes using GUVs made from lipid extracts of invertebrates

Biology Open, 2013
Summary Changes in the physical properties of the lipid matrix of cell membranes have repeatedly been proposed to underlie stresses associated with e.g. drought, cold and xenobiotics.
Hélène Bouvrais, Martin Holmstrup, Peter Westh, John H. Ipsen   +3 more
doaj   +1 more source