Results 81 to 90 of about 588,405 (243)
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
A Reliability Calculation Method for a Multistate System With Unidirectional Performance Sharing
IEEE AccessIn order to enhance reliability of engineering systems, multiple units within an engineering system are often strategically interconnected to achieve performance sharing.
Yao Sun, Jie Zhou, Zhili Sun, Zhe Wei
doaj +1 more source
Optimal Service Distribution in WSN Service System Subject to Data Security Constraints
Sensors, 2014 Services composition technology provides a flexible approach to building Wireless Sensor Network (WSN) Service Applications (WSA) in a service oriented tasking system for WSN.
Zhao Wu +3 more
doaj +1 more source
Turbulence near cyclic fold bifurcations in birhythmic media
, 2004 We show that at the onset of a cyclic fold bifurcation, a birhythmic medium composed of glycolytic oscillators displays turbulent dynamics. By computing the largest Lyapunov exponent, the spatial correlation function, and the average transient lifetime ...
A. Goldbeter +10 more
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Journal of Modern Power Systems and Clean Energy, 2013 Universal Generating Function (UGF) techniques have been applied to Multi-State System (MSS) reliability analysis, such as long term reserve expansion of power systems with high wind power penetration.
Hongtao Wang, Xu Liu, Chunyi Wang
doaj +1 more source
Finite difference quantum Toda lattice via equivariant K-theory
, 2005 We construct the action of the quantum group U_v(sl_n) by the natural correspondences in the equivariant localized $K$-theory of the Laumon based Quasiflags' moduli spaces. The resulting module is the universal Verma module.
Braverman, Alexander +1 more
core +3 more sources
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Generating Function for Particle-Number Probability Distribution in Directed Percolation
, 2005 We derive a generic expression for the generating function (GF) of the particle-number probability distribution (PNPD) for a simple reaction diffusion model that belongs to the directed percolation universality class. Starting with a single particle on a
Amit D J +13 more
core +1 more source