Results 81 to 90 of about 50,247 (212)

Unconjugated Multi-Epitope Peptides Adjuvanted with ALFQ Induce Durable and Broadly Reactive Antibodies to Human and Avian Influenza Viruses

Vaccines, 2023
An unconjugated composite peptide vaccine targeting multiple conserved influenza epitopes from hemagglutinin, neuraminidase, and matrix protein and formulated with a safe and highly potent adjuvant, Army Liposome formulation (ALFQ), generated broad and ...
Nimisha Rikhi, Clara J. Sei, Mangala Rao, Richard F. Schuman, Kellie A. Kroscher, Gary R. Matyas, Kevin Muema, Camille Lange, Aba Assiaw-Dufu, Elizabeth Hussin, Ousman Jobe, Carl R. Alving, Gerald W. Fischer   +12 more
doaj   +1 more source

An In-Depth Look at Recent Influenza Seasons and Vaccine Effectiveness [PDF]

, 2013
This paper aims to present an in-depth exploration of immunology, the influenza virus, vaccination, and vaccination’s effectiveness with respect to influenza.
Ricci, Ariana
core   +1 more source

Mixed‐mode membrane chromatography: mechanistic‐modeling‐based optimization and scale‐up of antibody charge variant separation using a novel membrane adsorber

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Efficient manufacturing of complex biopharmaceuticals increasingly relies on innovative downstream processing strategies. Membrane chromatography offers a promising alternative to resin‐based systems by enabling high‐throughput separations at elevated flow rates. Typically used in flow‐through mode, its industrial applications range
Jan Hedrich, Rita Steigmiller, Viktor Simaev, Romas Skudas, Michael Schulte, Mathias Hafner, Christian Frech   +6 more
wiley   +1 more source

Multivalent Epigraph Hemagglutinin Vaccine Protects against Influenza B Virus in Mice

Pathogens
Influenza B virus is a respiratory pathogen that contributes to seasonal epidemics, accounts for approximately 25% of global influenza infections, and can induce severe disease in young children.
Erika Petro-Turnquist, Brigette Corder Kampfe, Amber Gadeken, Matthew J. Pekarek, Eric A. Weaver   +4 more
doaj   +1 more source

Mucosal vaccination with recombinant adenovirus encoding nucleoprotein provides potent protection against influenza virus infection. [PDF]

PLoS ONE, 2013
Influenza vaccines that target the highly variable surface glycoproteins hemagglutinin and neuraminidase cause inconvenience of having vaccination every year.
So-Hee Kim, Joo Young Kim, Youngjoo Choi, Huan H Nguyen, Man Ki Song, Jun Chang   +5 more
doaj   +1 more source

Development and characterization of influenza M2 ectodomain and/or hemagglutinin stalk-based dendritic cell-targeting vaccines

Frontiers in Microbiology, 2022
A universal influenza vaccine is required for broad protection against influenza infection. Here, we revealed the efficacy of novel influenza vaccine candidates based on Ebola glycoprotein dendritic cell (DC)-targeting domain (EΔM) fusion protein ...
Titus Abiola Olukitibi, Titus Abiola Olukitibi, Zhujun Ao, Zhujun Ao, Hiva Azizi, Mona Mahmoudi, Mona Mahmoudi, Kevin Coombs, Darwyn Kobasa, Darwyn Kobasa, Gary Kobinger, Gary Kobinger, Xiaojian Yao, Xiaojian Yao   +13 more
doaj   +1 more source

Influenza Evolution and H3N2 Vaccine Effectiveness, with Application to the 2014/2015 Season [PDF]

, 2016
Influenza A is a serious disease that causes significant morbidity and mortality, and vaccines against the seasonal influenza disease are of variable effectiveness.
Deem, Michael W., Li, Xi
core   +2 more sources

Mitigating Health Disparities Through Empathetic Policymaking During Times of Crisis

Public Administration and Development, EarlyView.
ABSTRACT The COVID‐19 pandemic greatly exacerbated the existing disparities and inequities in health and healthcare among historically marginalized populations. Today, these impacts still echo. These persistent structured inequities erode the public's trust in government, lead to failure in public policies, and result in worse health consequences ...
Yali Pang, Brittany Keegan, Robyn D. McDougle   +2 more
wiley   +1 more source

Pandemic Influenza: Ethics, Law, and the Public\u27s Health [PDF]

, 2007
Highly pathogenic Influenza (HPAI) has captured the close attention of policy makers who regard pandemic influenza as a national security threat. Although the prevalence is currently very low, recent evidence that the 1918 pandemic was caused by an avian
Berkman, Benjamin E., Gostin, Lawrence O.   +1 more
core   +1 more source

Incidence and viral aetiologies of acute respiratory illnesses (ARIs) in the United States: a population-based study. [PDF]

, 2016
We conducted prospective, community-wide surveillance for acute respiratory illnesses (ARIs) in Rochester, NY and Marshfield, WI during a 3-month period in winter 2011.
Albertin, C, Blumkin, A, Donahue, JG, Gallivan, S, Lofthus, GK, Schnabel, KC, Shay, DK, Szilagyi, PG, Thompson, MG, Treanor, JJ   +9 more
core   +1 more source