Results 81 to 90 of about 42,982 (161)

mzLearn as a data-driven LC/MS signal detection algorithm that enables pre-trained generative models for untargeted metabolomics

Communications Chemistry
Metabolite alterations are linked to diseases, yet large-scale untargeted metabolomics remains constrained by challenges in signal detection and integration of diverse datasets for developing pre-trained generative models.
Leila Pirhaji, Jonah Eaton, Adarsh K. Jeewajee, Min Zhang, Matthew Morris, Maria Karasarides   +5 more
doaj   +1 more source

GC-HRMS processing tools for untargeted metabolomics [PDF]

, 2022
International audienceMetabolomics and related sciences use a combination of analytical and statistical approaches to qualitatively and quantitatively analyze small molecules present in a biological system to answer biological questions. Metabolomics and
Massias, Justine, Raux, Axel, Guitton, Yann, Royer, Anne-Lise, Rambaud, Lauriane, Le Bizec, Bruno   +5 more
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Untargeted Metabolomics Analysis Based on LC-QTOF-MS to Investigate the Phenolic Composition of Red and White Wines Elaborated from Sonicated Grapes

Foods
Ultrasounds are considered an emerging technology in the wine industry. Concretely, in 2019, the International Organization of Vine and Wine (OIV) officially approved their use for the treatment of crushed grapes to increase the level of phenolic ...
Alejandro Martínez-Moreno, Paula Pérez-Porras, Ana Belén Bautista-Ortín, Encarna Gómez-Plaza, Fernando Vallejo   +4 more
doaj   +1 more source

An untargeted metabolomics approach to wine micro-oxygenation [PDF]

, 2011
Micro-oxygenation is a common winemaking practice for red wine, that consist in a continuous addition of small amounts of oxygen into the wine in order to improve its color, aroma, texture and conservation time.
Arapitsas, Panagiotis, Perenzoni, Daniele, Vrhovsek, Urska, Di Blasi, S., Scholz, Matthias Uwe, Mattivi, Fulvio, Masuero, Domenico, Biondi Bartolini, A.   +7 more
core  

Normalizing Untargeted Periconceptional Urinary Metabolomics Data: A Comparison of Approaches

Metabolites, 2019
Metabolomics studies of the early-life exposome often use maternal urine specimens to investigate critical developmental windows, including the periconceptional period and early pregnancy.
Ana K. Rosen Vollmar, Nicholas J. W. Rattray, Yuping Cai, Álvaro J. Santos-Neto, Nicole C. Deziel, Anne Marie Z. Jukic, Caroline H. Johnson   +6 more
doaj   +1 more source

Exploratory analysis of metabolic changes using mass spectrometry data and graph embeddings

Scientific Reports
Mass spectrometry (MS)-based metabolomics analysis is a powerful tool, but it comes with its own set of challenges. The MS workflow involves multiple steps before its interpretation in what is denominate data mining.
Edwin Alvarez-Mamani, Florian Buettner, Cesar A. Beltran-Castanon, Alfredo J. Ibanez   +3 more
doaj   +1 more source

Comparative Antioxidant Activity and Untargeted Metabolomic Analyses of Sour Cherry Cultivars Based on Ultra-Performance–Time of Flight–Mass Spectrometry

Plants
This study was conducted for the comparative analysis of antioxidant activity and untargeted metabolomics of dark- and light-colored sour cherry cultivars grown in Canada.
Prabhjot Kaur, Ahmed G. Darwish, Islam El-Sharkawy, Ashutosh Singh, Jayasankar Subramanian   +4 more
doaj   +1 more source

Optimization of an Extraction Protocol for Untargeted Metabolomics of Vitis vinifera L. Leaves

Plants
Viticulture faces increasing challenges due to the susceptibility of Vitis vinifera L. to biotic and abiotic stresses, which trigger defense responses involving the synthesis of secondary metabolites. Untargeted metabolomics has become a powerful tool to
Laura Sánchez-Ochoa, Teresa Garde-Cerdán, Itziar Sáenz de Urturi, Miriam González-Lázaro, Eva P. Pérez-Álvarez   +4 more
doaj   +1 more source

Metabolic correlations between kidney and eye in a mouse model of oxygen-induced retinopathy and retinopathy of prematurity

BMJ Open Ophthalmology
Introduction Retinopathy of prematurity (ROP) is one of the leading causes of babies’ visual impairment and blindness. There is no effective prevention and treatment of ROP so far, and the shared genetic and developmental similarities among the brain ...
Jie Sun, Guoming Zhang, Yulin Zhang, Xiaofeng Lu, Zixin Fan, Yuhang Yang, Lijun Dong, Hui Qi, Yinsheng Zhang, Xiaoyan Chai, Dongting Wu, Hetian Lei   +11 more
doaj   +1 more source

Caracterización del metabolismo del glucógeno en neuronas y su implicación en la tolerancia a la hipoxia [PDF]

, 2012
[spa] La presencia de glucógeno en las neuronas ha sido motivo de controversia durante las pasadas décadas. Sin embargo, está aceptado que las neuronas expresan la maquinaria necesaria para sintetizar glucógeno, pero no para degradarlo.
Sáez Martínez, Isabel
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