Bacterial Metabolomics: Sample Preparation Methods
Biochemistry Research International, 2022 Metabolomics is a comprehensive analysis of metabolites existing in biological systems. As one of the important “omics” tools, the approach has been widely employed in various fields in helping to better understand the complex cellular metabolic states ...
Khairunnisa Mohd Kamal +5 more
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Mapping Analyte-Signal Relations in LC-MS Based Untargeted Metabolomics [PDF]
, 2017 The goal of untargeted metabolomics is to profile metabolism by measuring as many metabolites as possible. A major advantage of the untargeted approach is the detection of unexpected or unknown metabolites.
Mahieu, Nathaniel Guy
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Deciphering Blood Flow Restriction Training to Aid Lipid Lowering in Obese College Students through Untargeted Metabolomics [PDF]
(1) Objective: The aim of this study was to observe the lipid-lowering effects of blood flow restriction training (BFR) combined with moderate-intensity continuous training (MICT) in obese college students by observing lipid-lowering hormones and ...
Xianyou Cui +2 more
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Untargeted metabolomics suffers from incomplete data analysis [PDF]
, 2017 IntroductionUntargeted metabolomics is a powerful tool for biological discoveries. Significant advances in computational approaches to analyzing the complex raw data have been made, yet it is not clear how exhaustive and reliable are the data analysis ...
Richard Baran
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Untargeted Metabolomics Reveal Parenteral Nutrition-Associated Alterations in Pediatric Patients with Short Bowel Syndrome [PDF]
, 2022 Short bowel syndrome (SBS) is a major cause of intestinal failure (IF) that may require long-term parenteral nutrition (PN) support. However, long-term PN is accompanied by severe complications such as catheter-related blood stream infection (CRBSI) and ...
Lu Jiang +11 more
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Current Practice in Untargeted Human Milk Metabolomics [PDF]
, 2020 Human milk (HM) is considered the gold standard for infant nutrition. HM contains macro- and micronutrients, as well as a range of bioactive compounds (hormones, growth factors, cell debris, etc.).
José David Piñeiro-Ramos +7 more
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Validation of an LC-HRMS-based untargeted metabolomics analytical platform for a long-term clinical metabolomics study [PDF]
Untargeted metabolomics by LC-HRMS is a powerful tool when searching for new biomarkers to enhance our knowledge of pathophysiological processes. When used for large-scale clinical studies, it is crucial to have a comprehensive and robust setup and that ...
Pia Johansson, Heinsvig +5 more
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Metabolites, 2018 Bioactive compounds present in plant-based foods, and their metabolites derived from gut microbiota and endogenous metabolism, represent thousands of chemical structures of potential interest for human nutrition and health.
Ville Mikael Koistinen +24 more
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Optimised Untargeted Metabolomics Workflow for Human Urinary Extracellular Vesicles [PDF]
Extracellular vesicles (EVs) have been a key focus in biomarker discovery, with urinary EVs (uEVs), primarily derived from cells of the urogenital tract, providing valuable insights into kidney and urinary tract health and disease.
Taal, Maarten +9 more
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Large-scale untargeted LC-MS metabolomics data correction using between-batch feature alignment and cluster-based within-batch signal intensity drift correction [PDF]
, 2016 Introduction Liquid chromatography-mass spectrometry (LC-MS) is a commonly used technique in untargeted metabolomics owing to broad coverage of metabolites, high sensitivity and simple sample preparation. However, data generated from multiple batches are
Landberg, Rikard, +3 more
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