Results 11 to 20 of about 128,142 (116)
Regulation of CCN1 via the 3′-untranslated region [PDF]
Journal of Cell Communication and Signaling, 2013 The 3'-untranslated region (UTR) is known to be a critical regulator of post-transcriptional events that determine the gene expression at the RNA level. The gene CCN1 is one of the classical members of the matricellular CCN family and is involved in a number of biological processes during mammalian development.
Yosuke, Nakagawa +8 more
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Transcriptional Repression, a Novel Function for 3' Untranslated Regions [PDF]
European Journal of Biochemistry, 1995 The transcription rates of the rat serine protease inhibitor 2.3 and 2.1 genes (spi 2.3 and spi 2.1), which are normally very low and high, respectively, are inversely modulated during inflammation. Two growth‐hormone‐response elements (GHRE‐I and GHRE‐II) maintain the spi 2.1 gene under the stringent control of growth hormone [Le Cam, A., Pantescu, V.,
A, Le Cam, C, Legraverend
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Modulation of untranslated region alternative polyadenylation in glioma tumorigenesis
Biomedicine & Pharmacotherapy, 2021 RNA modification is an important form of regulation in cancer biology, that is capable of affecting cell proliferation, migration, other genetic characteristics of tumors, and protein expression. Recent research has shown that dysregulation of RNA modification plays an important role in glioma pathogenesis.
Yu-Long, Lan, Jianmin, Zhang
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Untranslated regions of mRNAs.
Genome biology, 2002 Gene expression is finely regulated at the post-transcriptional level. Features of the untranslated regions of mRNAs that control their translation, degradation and localization include stem-loop structures, upstream initiation codons and open reading frames, internal ribosome entry sites and various cis-acting elements that are bound by RNA-binding ...
MIGNONE, Flavio +3 more
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Ovine PRNP untranslated region and promoter haplotype diversity
Journal of General Virology, 2009 The diversity and possible contribution of non-coding regions of the prion protein (PrP) gene (PRNP) to transmissible spongiform encephalopathy susceptibility and PrP regulation are not fully known. This study defined ten ovine PRNP promoters and five untranslated region (UTR) haplotypes found in atypical and classical scrapie cases and healthy control
Ginny C, Saunders +6 more
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Evolution of the influenza A virus untranslated regions
Infection, Genetics and Evolution, 2011 In case of the influenza virus, untranslated regions are considered to possess plural functions. The specific packaging model suggests that each of eight segments contains a unique "packaging signal", situated within the untranslated region and coding regions at the 5' and 3' ends of the genomic RNA. In addition to packaging signal, UTRs play key roles
Yuki, Furuse, Hitoshi, Oshitani
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Translational medicine: untranslated regions and the stop codons
Bulletin of Russian State Medical University, 2016 4P medicine is impossible without an efficient transfer of advanced laboratory techniques (such as regenerative cell technology, high-throughput sequencing, genome editing, etc.) into clinical practice. Translational Medicine a new scientific field, designed to reduce the time of transfer of long-term achievements of fundamental scientific research in ...
REBRIKOV D.V., TARASOV V.V.
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Regulatory RNAs: Have mRNA Untranslated Regions Joined the Party?
PLoS Medicine, 2008 Thomas Hughes and Pamela Jones discuss the implications of a new study on the 5' non-coding region of vascular endothelial growth factor mRNA and its influence on gene expression.
Thomas A Hughes, Pamela F Jones
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Mapping the Pax6 3’ untranslated region microRNA regulatory landscape
BMC Genomics, 2018 PAX6 is a homeodomain transcription factor that acts in a highly dosage-sensitive manner to regulate the development and function of the eyes, nose, central nervous system, gut, and endocrine pancreas. Several individual microRNAs (miRNA) have been implicated in regulating PAX6 in different cellular contexts, but a more general view of how they ...
Bridget C. Ryan +6 more
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Genetic characterization of the coxsackievirus B2 3′ untranslated region
Journal of General Virology, 2001 The secondary structure of the 3′ untranslated region (3′UTR) of picornaviruses is thought to be important for the initiation of negative-strand RNA synthesis. In this study, genetic and biological analyses of the 3′ terminus of coxsackievirus B2 (CVB2), which differs from other enteroviruses due to the presence of five additional nucleotides prior to ...
Charlotta, Polacek, A Michael, Lindberg
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