Results 31 to 40 of about 36,901 (236)

In-vivo thrombolytic efficacy of RGD modified protein-polymer conjugated urokinase nanogels

Polymer Testing, 2021
It has been shown that an arginine-glycine-aspartic acid (RGD) modified pH-triggered delivery system for the urokinase-type plasminogen activator (uPA) is resistant to enzymatic degradation and improves thrombolytic ability in vitro.
Xia Liu, Ling-Li Jin, Ling-Ling Zhao, Ya-Chao Wang, Liping Zhang, Zheng-Zheng Huang, Hai-Qiang Jin, Jun-Ying Liu, Zhen-Jiang Liang, Xuan Liu, Hui Tan, Li-Jie Ren   +11 more
doaj   +1 more source

A novel tumor-activated ALA fusion protein for specific inhibition on the growth and invasion of breast cancer cells MDA-MB-231

Drug Delivery, 2017
Objective: The aim of this research was to develop a novel ALA fusion protein for target to the malignant cells surface with high uPAR expression and locally release of the scorpion toxin AGAP in an uPA-cleavable manner.
Xiufeng Liu, Xintong Liu, Suwen Sunchen, Meixia Liu, Chen Shen, Juanjuan Wu, Wanli Zhao, Boyang Yu, Jihua Liu   +8 more
doaj   +1 more source

FIGO statement on emergency contraception. [PDF]

Int J Gynaecol Obstet
Abstract Emergency contraception remains an essential component of comprehensive contraceptive care and reproductive autonomy. Despite being safe, highly effective, and associated with almost no absolute medical contraindications or age limits, emergency contraception is often underutilized due to systemic barriers, limited access, persistent ...
Koch M, Kasliwal A, Kiarie J, Elkholy N, Ahsan A, Sridhar A.   +5 more
europepmc   +2 more sources

National Recommendations for Pharmacoeconomic Evaluations Reporting for Reimbursement and Procurement of New Pharmaceutical Applications in Egypt [PDF]

Global Journal on Quality and Safety in Healthcare
Introduction To improve resource allocation within our healthcare system, the Egyptian Authority for Unified Procurement, Medical Supply and the Management of Medical Technology (UPA) and Universal Health Insurance Authority (UHIA) established a joint ...
Mary Gamal, Amal Samir Sedrak, Gihan Hamdy Elsisi, Ahmed Elagamy, Ahmed Seyam, Mariam Eldebeiky, Randa Eldessoki   +6 more
doaj   +1 more source

Implementación de un Sistema Informático para mejorar el seguimiento de los egresados de la Universidad Politécnica Amazónica – UPA, Bagua Grande, Utcubamba, Amazonas, Perú – 2020 [PDF]

, 2023
La presente tesis fue desarrollada bajo la línea de investigación de gestión de tecnologías de la información con la metodología XP, el sistema se realizó con el fin de mejorar el seguimiento de los egresados de la Universidad Politécnica Amazónica – UPA,
Díaz Guerrero, Imer Hobet
core  

Mitogenome analysis of a green tide forming Ulva from California, USA confirms its identity as Ulva expansa (Ulvaceae, Chlorophyta)

Mitochondrial DNA. Part B. Resources, 2018
An unknown species of marine sea lettuce was observed forming green tides consecutive years from 2014 to 2016 in Seaside, California. This Ulva sp. was similar in thallus size and shape to U. expansa.
Jeffery R. Hughey, Kathy Ann Miller, Paul W. Gabrielson   +2 more
doaj   +1 more source

Deficiency of Urokinase Plasminogen Activator May Impair β Cells Regeneration and Insulin Secretion in Type 2 Diabetes Mellitus

Molecules, 2019
: Background: The relationship between urokinase-type plasminogen activator (uPA) and the development of type 2 diabetes mellitus (T2DM) was investigated in the study by using mice and cell models, as well as patients with T2DM.
Chung-Ze Wu, Shih-Hsiang Ou, Li-Chien Chang, Yuh-Feng Lin, Dee Pei, Jin-Shuen Chen   +5 more
doaj   +1 more source

Establishing the ‘irrefutable facts’ about the OUN and UPA: the role of the working group of historians on OUN-UPA activity in mediating memory-based conflict in Ukraine [PDF]

, 2018
There has been an increasing scholarly interest in the role of history commissions and historians in the processes of truth-seeking, reconciliation, and mitigation of conflicts between groups divided by the past.
Myshlovska, Oksana, Oksana Myshlovska
core   +1 more source

Clinical characteristics of vulnerable populations hospitalized and diagnosed with COVID-19 in Buenos Aires, Argentina

Scientific Reports, 2021
There is not in Argentina publications regarding the presentation of patients with COVID-19 requiring hospitalized and emergency care in vulnerable populations (lower incomes and less education tend at greater risk for poor health status and healthcare ...
A. Yacobitti, L. Otero, V. Doldan Arrubarrena, J. Arano, S. Lage, M. Silberman, M. Zubieta, I. Erbetta, P. Danei, G. Baeck, V. Vallejos, F. Cavalli, N. Calderón, M. Di Gregorio, V. Hernandez, D. Bruno, B. Rodera, I. Macherett, M. Parisi, M. Gallastegui, A. Paz, R. Bernardi, S. Azcárate, A. Hraste, I. Caridi, L. Boechi, P. Salgado, S. Kochen   +27 more
doaj   +1 more source

Age-related characteristics of the content and activity of certain components of the blood fibrinolytic system in cases of uterine cancer

Сибирский научный медицинский журнал
Uterine cancer (UC) is the third most common cancer in women in Russia. Knowledge of age-specific features of the fibrinolytic system in patients with UC can be useful in terms of improving its pathogenetic therapy.
I. V. Kaplieva, V. R. Zakharchenko, E. M. Frantsiyants, N. K. Guskova, E. V. Verenikina, N. A. Maksimova, S. N. Dimitriadi, M. M. Sergeeva, M. G. Ilchenko, J. A. Pogorelova, L. K. Trepitaki   +10 more
doaj   +1 more source