Results 71 to 80 of about 36,901 (236)

Elevated levels of serum urokinase plasminogen activator predict poor prognosis in hepatocellular carcinoma after resection

BMC Cancer, 2019
Background Urokinase plasminogen activator (uPA) is an extracellular matrix-degrading protease that is involved in the invasiveness and progression of cancer.
Ming-Chao Tsai, Yi-Hao Yen, Kuo-Chin Chang, Chao-Hung Hung, Chien-Hung Chen, Ming-Tsung Lin, Tsung-Hui Hu   +6 more
doaj   +1 more source

The Upas Tree

AJN, American Journal of Nursing, 1913
Mode of access: Internet.
openaire   +1 more source

Towards Sustainable Urbanization and Zero–Carbon Urban Life: A Case Study of BRICS Countries Between 1992 and 2020

Natural Resources Forum, EarlyView.
ABSTRACT Urban factors play a critical role in efforts to reduce greenhouse gas emissions and adapt to climate change. In this regard, this study aims to examine the impact of urbanization and its components (e.g., urban population growth [UPG], population in the largest city [ULC], population in urban agglomerations [UPA] of more than 1 million, and ...
Korkmaz Yildirim, Tunahan Haciimamoglu
wiley   +1 more source

Abstract 4401: Antibody-mediated targeting of the uPA proteolytic activity neutralizes uPA functions in vivo

, 2010
Urokinase-type plasminogen activator (uPA) plays a central role in tissue remodeling processes, during both normal physiological conditions and cancer progression.
John Rømer, Birgitte Rønø, Kasper Almholt, Morten G. Rasch, Ida K. Lund, Annika Jögi, Gunilla Høyer-Hansen, Niels Behrendt, Leif R. Lund, Henrik Gårdsvoll   +9 more
core   +1 more source

Aphid and endosymbiont sensitivity to heatwaves is misaligned across life stages

Insect Science, EarlyView.
Aphids depend on the obligate symbiont Buchnera aphidicola, which may constrain thermal tolerance. Using a factorial heatwave experiment, we exposed nymphs and adults to moderate or extreme temperatures and measured fitness and symbiont responses.
Evatt Chirgwin, Qiong Yang, Paul A. Umina, Xuan Cheng, Xinyue Gu, Alex Gill, Ary A. Hoffmann   +6 more
wiley   +1 more source

Liver lipids in cDNA-uPA/SCID mice.

, 2022
Liver lipids in cDNA-uPA/SCID mice.
Mehdi Nassiri (12519477), Núria Morral (5172077), Xiao-Ming Yin (109741), Romil Saxena (584525)   +3 more
core   +1 more source

System of plasminogen regulators in the skin of intact uPA gene-knockout C57BL/6-PlautmI.IBug-This Plau6FDhu/GFDhu mice and in a model of chronic neurogenic pain

Исследования и практика в медицине, 2019
Purpose of the study. Studying the components of the cascade of plasminogen (PG) regulator in the skin of intact uPA (urokinase plasminogen activator) gene-knockout mice and in a model of chronic neurogenic pain (CNP).Materials and methods.
E. M. Frantsiyants, E. I. Surikova, I. V. Kaplieva, I. V. Neskubina, L. S. Kozlova, V. A. Bandovkina, L. K. Trepitaki, V. V. Pozdnyakova   +7 more
doaj   +1 more source

Fishing Activity Affected Odontocete Cetacean Distribution in a Marine Protected Area in the East China Sea

Integrative Zoology, EarlyView.
Spatiotemporal distribution of odontocete cetaceans within China's Jiushan Archipelago National Nature Reserve was investigated. Fishing vessels significantly reduced both cetacean acoustic detections and feeding activity, whereas gillnets selectively suppressed cetacean feeding behavior without affecting overall cetacean detection rates.
Yifan Liu, Zitong Zhou, Peng Ding, Yu Pan, Zhi Yang, Haochi Wang, Fangqiao Wang, Tianshi Wei, Pengxiang Duan, Tomonari Akamatsu, Zhitao Wang   +10 more
wiley   +1 more source

Decision impact and feasibility of different ASCO-recommended biomarkers in early breast cancer: Prospective comparison of molecular marker EndoPredict and protein marker uPA/PAI-1.

PLoS ONE, 2017
BackgroundAdjuvant therapy decisions in early breast cancer are based on accurate risk assessment. Urokinase plasminogen activator (uPA) and plaminogen activator inhibitor-1 (PAI-1) have been the first biomarkers in hormone receptor (HR) positive breast ...
Johannes Ettl, Evelyn Klein, Alexander Hapfelmeier, Kirsten Grosse Lackmann, Stefan Paepke, Christoph Petry, Katja Specht, Laura Wolff, Heinz Höfler, Marion Kiechle   +9 more
doaj   +1 more source

Distinct Immunometabolic Profiles in Finnish and Russian Karelian Adolescents With Contrasting Allergy Risk

Allergy, EarlyView.
We compared Finnish and Russian Karelian adolescents with contrasting allergy burden using integrated proteomic, metabolomic, and transcriptomic profiling. Finnish adolescents showed a broader pro‐inflammatory PBMC secretory profile consistent with a low‐grade inflammatory phenotype.
Nanna Fyhrquist, Matilda Riskumäki, Piia Karisola, Anni Nieminen, Tiina Laatikainen, Hanna Sinkko, Laura Paalanen, Pekka Jousilahti, Erkki Vartiainen, Mika J. Mäkelä, Tari Haahtela, Harri Alenius   +11 more
wiley   +1 more source