Results 211 to 220 of about 75,036 (262)

Supplementary Figure 5 from Inhibition of Akt Potentiates 2-DG–Induced Apoptosis via Downregulation of UPR in Acute Lymphoblastic Leukemia

, 2023
Joanna DeSalvo, Jeffim N. Kuznetsov, Jianfeng Du, Gilles M. Leclerc, Guy J. Leclerc, Théodore J. Lampidis, Julio C. Barredo   +6 more
openalex   +1 more source

Is Ferroptosis the Mechanistic Bridge Connecting Iron Dysregulation to Muscle Wasting and Functional Decline in Aging?

Aging Cell, Volume 25, Issue 2, February 2026.
This work proposes ferroptosis as a mechanistic driver of age‐related muscle dysfunction, whereby iron dyshomeostasis and impaired antioxidant capacity promote lipid peroxidation, and eventually trigger ferroptosis, leading to muscle wasting, and ultimately contributing to weakness and functional decline with aging.
Rola S. Zeidan, Simon Reinhard, Anna Picca, Emanuele Marzetti, Christiaan Leeuwenburgh, James F. Collins, Stephen D. Anton   +6 more
wiley   +1 more source

Local species‐specific effect of trees and shrubs on the incidence of the millet head miner, Heliocheilus albipunctella (Lepidoptera, Noctuidae)

Agricultural and Forest Entomology, Volume 28, Issue 1, Page 38-48, February 2026.
Abstract Understanding the interactions between crop pests, natural enemies and semi‐natural habitats in agricultural landscapes is crucial for developing ecology‐based pest management in agroecosystems. In the present study, we investigated the local‐scale species‐specific effect of tree and shrub cover and diversity on the incidence and natural pest ...
Ahmadou Sow, Julien Winkelmann, Alexandre Aebi, Thierry Brévault   +3 more
wiley   +1 more source

Modeling the UPR in neurodegenaration

Frontiers in Neuroinformatics, 2016
Theocharopoulou Georgia, Bobori Catherine   +1 more
openaire   +1 more source

The UPR-oxidative stress nexus in diabetes and obesity: Exploring innovative therapeutic approaches for metabolic control

Clinton Ayodeji Akanbi, Ojo Oluwafemi Adeleke   +1 more
openalex   +1 more source

Ricin-A-chain (RTA) inhibits the unfolded protein response (UPR) in mammalian cells

, 2010
Chao-Ting Wang
openalex   +1 more source

UPR Project at BCU Sudan Stakeholder Report [PDF]

, 2021
Amna Nazir, Alice Storey, Jon Yorke, Catie Harvey   +3 more
openalex  

COMPARISON OF BiP AND Hsp70i AS MARKERS OF UNFOLDED PROTEIN RESPONSE (UPR) IN SEGMENTAL AND NONSEGMENTAL VITILIGO

, 2022
Boedhy Setyanto, Handono Kalim, Sri Poeranto, Dhelya Widasmara   +3 more
openalex   +1 more source

Gonadal function in males with WFS1 spectrum disorder (Wolfram syndrome)—A European cohort perspective

Andrology, Volume 14, Issue 2, Page 398-410, February 2026.
Abstract Background WFS1 spectrum disorder, also known as Wolfram syndrome (WS) is an ultra‐rare (<1:500,000; ORPHA: 3463) monogenic (OMIM #222300) progressive neuroendocrine and neurodegenerative disorder, characterised by early‐onset insulin‐dependent diabetes, optic atrophy, central diabetes insipidus and sensi‐neuronal deafness.
Julia Rohayem, Olivia Cunningham, Denise Williams, Joachim Wistuba, Liam McCarthy, Timothy G. Barrett, Renuka P. Dias   +6 more
wiley   +1 more source

Trichostatin A Sensitizes Tumor Cells to Apoptosis Induced by Soluble Trimeric TRAIL‐Expressing Human Mesenchymal Stromal Cells

Cancer Science, Volume 117, Issue 2, Page 456-467, February 2026.
Human mesenchymal stromal cells (MSCs) were engineered to secrete an isoleucine‐zippered soluble trimeric TRAIL (SCZT) and evaluated with trichostatin A (TSA) to overcome TRAIL resistance. TSA upregulated DR5 and amplified caspase‐8–dependent apoptosis in vitro; in vivo, tumor‐homing MSCs combined with TSA suppressed the growth of both TRAIL‐sensitive ...
Ryosuke Uchibori, Ken Ohmine, Keiya Ozawa   +2 more
wiley   +1 more source