Results 201 to 210 of about 111,661 (295)

Response of cereals to intercropping with non‐food crops in tropical and subtropical regions: A meta‐analysis

Agronomy Journal, Volume 118, Issue 3, May/June 2026.
Abstract Intercropping cereals with non‐food intercrops (NFICs) provides a means to enhance cereal productivity while providing additional benefits such as improved soil health or forage production. We conducted a meta‐analysis to investigate the effect of NFICs on cereal yields, cereal nitrogen uptake, and striga (Striga spp.) infestation, using 874 ...
Kamarou‐Dine Seydou, Pierre G. Tovihoudji, Sissou Zakari, Pierrot Lionel Yemadje, P. B. Irénikatché Akponikpè, Charles L. Bielders   +5 more
wiley   +1 more source

Dusp15 modulates mtHsp70 Thr116 phosphorylation state to preserve mito-UPR and attenuate cardiac dysfunction in diabetic cardiomyopathy. [PDF]

Cardiovasc Diabetol
Liu Y, Shi H, Li C, Zhuang H, Li Y, He X, Jiang Y, Jin Z, Guo Z, Ong S, Wang Y, Chang X, An G, Wang J.   +13 more
europepmc   +1 more source

Fucoxanthin Ameliorates MASLD by Directly Targeting GRP78 to Restore ER Homeostasis and Activate AMPK Signaling

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Proposed model of fucoxanthin in ameliorating MASLD via the GRP78‐AMPK axis. In MASLD, excessive lipid accumulation (FFA, TG, DNL) leads to ER stress activation (upregulation of CHOP, ATF6, IRE1) and GRP78 dysfunction, promoting hepatic lipid droplet (LD) formation. Fucoxanthin directly binds to GRP78, which in turn activates AMPK signaling.
Lin Zhang, Ruifen Zhang, Yu Wu, Binbin Chen, Chao Wang, Cheng Wang, Zhengshun Wen, Jingui Zhang, Haibin Tong, Liang Hong   +9 more
wiley   +1 more source

Unfolded Protein Response as a Therapeutic Target: 4-(Heptyloxy)phenol Induces Programmed Cell Death in Ewing Sarcoma. [PDF]

Mol Cancer Ther
Zhang N, Perez M, Jenkins GN, Horton TM, Gilbertson SR, Pati D.   +5 more
europepmc   +1 more source

Liver Gene Therapy in Fabry Disease Mice With Low Doses of rAAV2/8 Expressing a Codon‐Optimized hGLA cDNA Results in Long‐Term Disease Correction

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
AAV‐mediated gene therapy targets the liver to produce and secrete into circulation functional α‐Gal A, which is taken up by tissues to reduce glycosphingolipid accumulation and prevent disease progression in juvenile Fabry mice, even at low AAV doses. ABSTRACT Fabry disease (FD) is an X‐linked lysosomal storage disorder caused by mutations in the GLA ...
Himanshi Saxena, Rossana Domenis, Giulia Romano, Jessica Biasizzo, Martina Ferro, Dania Ferino, Antonio Vicidomini, Alessandra Iaconcig, Giulia Bortolussi, Lorena Zentilin, Andrea Dardis, Andrés F. Muro   +11 more
wiley   +1 more source

Filamin A phosphorylation at S2152: a molecular switch fueling cancer and neurodegeneration. [PDF]

Cell Commun Signal
Burns LH, Romero A.
europepmc   +1 more source

Identification of a Novel De Novo Heterozygous SEC61A1 Variant in a Patient With Severe Congenital Neutropenia

Molecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.
Severe congenital neutropenia can be caused by rare SEC61A1 variants. We report a child with SCN showing granulocytic maturation arrest and abnormal immunophenotype, carrying a novel de novo SEC61A1 p.Trp379Arg variant, expanding the phenotypic and genetic spectrum of SEC61A1‐associated SCN.
Zixuan Wang, Hui Jing, Yuhan Chen, Ling Zhong, Jiyun Yang   +4 more
wiley   +1 more source

KIF5B-driven unfolded protein response reprograms breast cancer immunosuppressive microenvironment for single-cell guided therapeutic targeting. [PDF]

Discov Oncol
Liu Y, Li S, Luo Z, Xia Y, Zhang P.
europepmc   +1 more source

Proteolytic control of mitochondrial protein translocases

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Mitochondria are essential organelles that drive numerous cellular processes, including energy metabolism, ion homeostasis, and programmed cell death. This functional versatility relies on a highly dynamic proteome whose composition is continuously remodeled to meet changing cellular and environmental demands.
Lara Kroczek, Thomas Langer
wiley   +1 more source

The integrated stress response in apicomplexan and trypanosomatid parasites: balancing survival and pathogenesis. [PDF]

Front Immunol
Hammi I, Darif D, Arnoult D.
europepmc   +1 more source