Results 181 to 190 of about 111,661 (295)

A Cross‐Disease Microglial Transcriptional Program Characterizes Neurodegeneration and Highlights SPP1 as a Biomarker

Glia, Volume 74, Issue 6, June 2026.
Distinct microglial subpopulations are depicted, highlighting variations in gene expression and functional roles in response to specific disease conditions and the complexity of microglial activation and differentiation in neurodegeneration. ABSTRACT Microglial cells are key players in maintaining brain homeostasis and responding to pathological ...
Alessandro Palma, Roberta Stefanelli, Francesco Trenta, Chiara Projetti, Greta Massa, Sonia Canterini, Maria Teresa Fiorenza   +6 more
wiley   +1 more source

Activation of unfolded protein response pathways promotes keratinocyte differentiation and ameliorates psoriasis phenotypes. [PDF]

Cell Stress Chaperones
Zhang Z, Tan M, Liu X, Wang W, Chen X, Peng C, Zhao S, Wu L.   +7 more
europepmc   +1 more source

Inhibition of PLA2G15 Alleviates Palmitic Acid‐Induced Lysosomal Membrane Permeabilization in Human Nucleus Pulposus Cells During Intervertebral Disc Degeneration

JOR SPINE, Volume 9, Issue 2, June 2026.
LMP is responsible for lysosomal dysfunction in IDD. The lipid composition changes in the lysosomal membrane, mediated by PLA2G15, are the cause of LMP. The C/EBPα significantly promotes PLA2G15 expression under PA overload stress. Inhibition of PLA2G15 alleviates PA‐induced LMP by inhibiting the hydrolysis of lysosomal membrane phospholipids. ABSTRACT
Liqun Duan, Jiang Jiang, Shuangshuang Tu, Chuanfu Li, Yijun Dong, Yongjin Li, Wenzhi Zhang, Xi Chen   +7 more
wiley   +1 more source

Deciphering the interplay between hypoxia, angiogenesis, and endoplasmic reticulum stress in carcinogenesis: A narrative review. [PDF]

World J Exp Med
Bhardwaj S, Pandey S, Ghosh DK, Sharma T, Jain BP.   +4 more
europepmc   +1 more source

Changement climatique et agriculture : Une sélection des compétences du Cirad [PDF]

, 2015
CIRAD-PERSYST-UPR AIDA - FRA
core  

Oral Microbiome Resilience During SARS‐CoV‐2 Infection and Diversity Shifts After COVID‐19 Vaccination in a Hispanic Population

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
The oral microbiome in Hispanics remains largely resilient during mild SARS‐CoV‐2 infection, showing minimal diversity changes, while COVID‐19 vaccination induces increased microbial evenness and compositional shifts. These findings highlight limited infection impact but suggest vaccination transiently reshapes oral microbial ecology.
Daniela Vargas‐Robles, Jean L. Santos Agrait, Jaleniz Suárez‐Pérez, Frances Vázquez, Anelisse Dominicci‐Maura, Carlos A. Sariol, Carmen Zorrilla, Josefina Romaguera, Filipa Godoy‐Vitorino   +8 more
wiley   +1 more source

Multi-omics analyses related to unfolded protein response in prostate cancer implicate pro-tumor role of IFRD1. [PDF]

Front Immunol
Xue Y, Huang E, Luo C, Qian Y, Wu T, Chu C, Shi F, Chen S, Zhang D, Chen W, Huang W, Wang P, Chen H, Cheng Y, Fan Y.   +14 more
europepmc   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

Ligand-Exchange-Induced Growth of NiCo-LDH on Halloysite for Enhanced Flame Retardancy of Unsaturated Polyester Resin. [PDF]

ACS Omega
Wang S, Liu Y, Duan C, Meng W, Xie J, Xu J.   +5 more
europepmc   +1 more source

Modeling the UPR in neurodegenaration

Frontiers in Neuroinformatics, 2016
Theocharopoulou Georgia, Bobori Catherine   +1 more
openaire   +1 more source